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Chemical Structure| 1379445-54-1 Chemical Structure| 1379445-54-1

Structure of CRTh2 antagonist 1
CAS No.: 1379445-54-1

Chemical Structure| 1379445-54-1

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CRTh2 antagonist 1是 CRTh2 的拮抗剂,IC50 值为89 nM。

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Product Details of CRTh2 antagonist 1

CAS No. :1379445-54-1
Formula : C23H25N3O5S
M.W : 455.53
SMILES Code : O=C(O)CC1=C(C)N(CC2=CC=CC=C2S(=O)(N3CCOCC3)=O)N=C1C4=CC=CC=C4
MDL No. :MFCD31657432

Safety of CRTh2 antagonist 1

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of CRTh2 antagonist 1

GPCR

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT02002208 Atopic Dermatitis Phase 2 Completed - United Kingdom ... More >> University of Sheffield Sheffield, United Kingdom Less <<
NCT00784732 Seasonal Allergic Rhinitis Phase 2 Completed - Canada ... More >> Novartis Investigator Site Toronto, Canada Less <<
NCT02660489 Asthma Rhinov... More >>irus Picornaviridae Infections Common Cold Less << Phase 2 Unknown February 2018 United Kingdom ... More >> St Mary's Hospital Recruiting London, Greater London, United Kingdom, W2 1PG Contact: Hugo Farne, BMBCh MA    07590 250487    asthma.trial@imperial.ac.uk    Contact: Maria-Belén Trujillo-Torralbo, BSc    07590 250487    asthma.trial@imperial.ac.uk Less <<
NCT02381496 Healthy Phase 1 Completed - -
NCT02002208 - Completed - -
NCT01561690 Asthma Phase 2 Completed - -
NCT03567694 Asthma Phase 1 Not yet recruiting October 10, 2019 -
NCT02031679 Chronic Idiopathic Urticaria Phase 2 Completed - United States, Maryland ... More >> Johns Hopkins Asthma and Allergy Center Baltimore, Maryland, United States, 21224-6821 Less <<
NCT02031679 - Completed - -

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.20mL

0.44mL

0.22mL

10.98mL

2.20mL

1.10mL

21.95mL

4.39mL

2.20mL

 

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