Structure of Aducanumab
CAS No.: 1384260-65-4
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Aducanumab is a humanized IgG1 monoclonal antibody that clears β-amyloid deposits by binding to β-amyloid. Aducanumab has potential for research in Alzheimer's disease.
Synonyms: BIIB037
4.5
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Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
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CAS No. : | 1384260-65-4 |
M.W : | 146.2 kDa |
SMILES Code : | NONE |
Synonyms : |
BIIB037
|
GHS Pictogram: |
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Signal Word: | Warning |
Hazard Statements: | H302-H315-H319 |
Precautionary Statements: | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT04924140 | Healthy Volunteers | PHASE1 | COMPLETED | 2021-10-01 | Anaheim Clinical Trials, LLC, ... More >>Anaheim, California, 92801, United States|Qps-Mra, Llc, South Miami, Florida, 33143, United States Less << |
NCT04241068 | Alzheimer's Disease | PHASE3 | TERMINATED | 2024-07-22 | University of Alabama at Birmi... More >>ngham, Birmingham, Alabama, 35233, United States|Banner Alzheimer's Institute, Phoenix, Arizona, 85006, United States|Dignity Health, Phoenix, Arizona, 85013, United States|Banner Sun Health Research Institute, Sun City, Arizona, 85351, United States|Center for Neurosciences, Tucson, Arizona, 85718, United States|Neurology Center of North Orange County, Fullerton, California, 92835, United States|UCI MIND, Irvine, California, 92607, United States|University of California San Diego Medical Center, La Jolla, California, 92037, United States|Senior Clinical Trials, Inc., Laguna Hills, California, 92653, United States|USC Keck School of Medicine, Los Angeles, California, 90033, United States|Mary S. Easton Center for Alzheimer's Disease Research, UCLA, Los Angeles, California, 90095, United States|Pacific Neuroscience Medical Group, Oxnard, California, 93030, United States|Stanford Hospital and Clinics, Palo Alto, California, 94304, United States|Anderson Clinical Research, Redlands, California, 92374, United States|Pacific Research Network, Inc, San Diego, California, 92103, United States|UCSF - Memory and Aging Center, San Francisco, California, 94143, United States|Syrentis Clinical Research, Santa Ana, California, 92705, United States|California Neuroscience Research Medical Group Inc., Sherman Oaks, California, 91403, United States|University of Colorado Denver, Aurora, Colorado, 80045, United States|IMMUNOe International Research Centers, Centennial, Colorado, 80112, United States|Yale University, Fairfield, Connecticut, 06824, United States|Invicro, New Haven, Connecticut, 06510, United States|Yale University School Of Medicine, New Haven, Connecticut, 06510, United States|Research Center for Clinical Studies, Inc., Norwalk, Connecticut, 06851, United States|Georgetown University Clinical Research Unit (CRU), Washington, District of Columbia, 20007, United States|JEM Research, Atlantis, Florida, 33462, United States|Bradenton Research Center, Inc, Bradenton, Florida, 34205, United States|Brain Matters Research, Delray Beach, Florida, 334405, United States|Neuropsychiatric Research Center of Southwest Florida, Fort Myers, Florida, 33912, United States|Infinity Clinical Research, LLC, Hollywood, Florida, 33024, United States|Jacksonville Center for Clinical Research, Jacksonville, Florida, 32216, United States|Mayo Clinic in Florida, Jacksonville, Florida, 33462, United States|University of Miami, Miami, Florida, 33136, United States|Miami Jewish Health System, Inc, Miami, Florida, 33180, United States|Renstar Medical Research, Ocala, Florida, 34470, United States|Accelerated Enrollment Solutions (AES), Orlando, Florida, 32162, United States|Clinical Neuroscience Solutions, Inc., Orlando, Florida, 32801, United States|Accelerated Enrollment Solutions (AES), Orlando, Florida, 32806, United States|Palm Beach Neurological Center, Palm Beach Gardens, Florida, 33410, United States|Quantum Laboratories Inc., Pompano Beach, Florida, 33064, United States|Axiom Clinical Research of Florida, Tampa, Florida, 33609, United States|Stedman Clinical Trials, LLC, Tampa, Florida, 33613, United States|USF Health Byrd Institute, Tampa, Florida, 33616, United States|Meridien Research, Tampa, Florida, 33634, United States|Premiere Research Institute, West Palm Beach, Florida, 33407, United States|Cleveland Clinic Florida - Weston, Weston, Florida, 33331, United States|Emory University Cognitive Neurology Clinic & ADRC, Atlanta, Georgia, 30329, United States|Medical Research Health and Education Foundation, Inc, Columbus, Georgia, 31909, United States|NeuroStudies.net, LLC, Decatur, Georgia, 30033, United States|Alexian Brothers Medical Center - Neuroscience Research Institute, Elk Grove Village, Illinois, 60007, United States|Advocate Lutheran General Hospital, Park Ridge, Illinois, 60068, United States|Fort Wayne Neurological Center, Fort Wayne, Indiana, 46804, United States|Indiana University School of Medicine, Indianapolis, Indiana, 46202, United States|Josephson, Wallack, Munshower Neurology, P.C., Indianapolis, Indiana, 46256, United States|University of Kansas Medical Center Research Institute, Inc., Fairway, Kansas, 66205, United States|Ascension Via Christi Research, a division of Ascension Via Christi Hospitals Wichita, Inc., Wichita, Kansas, 67214, United States|Baptist Health Lexington, Lexington, Kentucky, 40503, United States|McLean Hospital, Belmont, Massachusetts, 02474, United States|Beth Israel Deaconess Medical Center, Boston, Massachusetts, 02215, United States|Brigham and Women's Hospital Department of Neurology, Boston, Massachusetts, 02215, United States|ActivMed Practices & Research, Inc., Methuen, Massachusetts, 01844, United States|Boston Center for Memory, Newton, Massachusetts, 02459, United States|Donald S. Marks, M.D., P.C., Plymouth, Massachusetts, 02360, United States|Mayo Clinic, Rochester, Michigan, 55902, United States|Hattiesburg Clinic, PA, Hattiesburg, Mississippi, 39401, United States|Washington University, Saint Louis, Missouri, 63108, United States|Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, Nevada, 89106, United States|Las Vegas Medical Research, Las Vegas, Nevada, 89113, United States|ActivMed Practices & Research, Inc., Portsmouth, New Hampshire, 03801, United States|Advanced Memory Research Inst. of NJ, PC, Toms River, New Jersey, 08755, United States|Albany Medical College, Albany, New York, 12208, United States|Empire Neurology, PC, Latham, New York, 12110, United States|New York University Medical Center PRIME, New York, New York, 10016, United States|Weill Cornell Medical College (WCMC) - Judith Jaffe Multiple Sclerosis Center (JJMSC), New York, New York, 10021, United States|Mount Sinai School of Medicine, New York, New York, 10029, United States|University of Rochester, Rochester, New York, 14620, United States|AMC Research, LLC, Charlotte, North Carolina, 28270, United States|Raleigh Neurology Associates, Raleigh, North Carolina, 27607-6010, United States|Gastroenterology Associates of the Piedmont, Winston-Salem, North Carolina, 27103, United States|Wake Forest Baptist Health, Winston-Salem, North Carolina, 27157-1207, United States|Cleveland Clinic Foundation, Cleveland, Ohio, 44195, United States|Ohio State University Wexner Medical Center, Columbus, Ohio, 43210, United States|Lynn Health Science Institute, Oklahoma City, Oklahoma, 73112, United States|Lehigh Center for Clinical Research, LLC, Allentown, Pennsylvania, 18104, United States|The Clinical Trial Center, LLC, Jenkintown, Pennsylvania, 19046, United States|Penn Memory Center, Philadelphia, Pennsylvania, 19104, United States|University of Pittsburgh, Pittsburgh, Pennsylvania, 15261, United States|Northeastern Pennsylvania Memory and Alzheimer's Center, Wilkes-Barre, Pennsylvania, 18705, United States|Rhode Island Mood & Memory Research Institute, East Providence, Rhode Island, 02914, United States|Rhode Island Hospital, Providence, Rhode Island, 02903, United States|Butler Hospital, Providence, Rhode Island, 02906, United States|Roper St. Francis Healthcare, Charleston, South Carolina, 29401, United States|Medical University of South Carolina (MUSC), Charleston, South Carolina, 29425, United States|Neurology Clinic, PC, Cordova, Tennessee, 38018, United States|Senior Adult Specialty Research, Austin, Texas, 33410, United States|UT Southwestern Medical Center, Dallas, Texas, 75390-9129, United States|Baylor College of Medicine, Houston, Texas, 77030, United States|Clinical Trial Network, Houston, Texas, 77074, United States|University of Utah Health Sciences Center, Salt Lake City, Utah, 84108, United States|The Memory Clinic, Bennington, Vermont, 05201, United States|National Clinical Research Inc.-Richmond, Richmond, Virginia, 23294, United States|University of Washington Medical Centre, Seattle, Washington, 98104-2499, United States|Kingfisher Cooperative, LLC, Spokane, Washington, 99202, United States|Medical College of Wisconsin, Inc., Milwaukee, Wisconsin, 53226, United States|The Prince Charles Hospital, Chermside, New South Wales, 4032, Australia|St Vincent's Hospital Sydney, Darlinghurst, New South Wales, 2010, Australia|Central Coast Neurosciences Research (Erina), Erina, New South Wales, 2250, Australia|KaRa Institute of Neurological Diseases, Macquarie Park, New South Wales, 2113, Australia|Box Hill Hospital, Box Hill, Victoria, 3128, Australia|Austin Health, Heidelberg West, Victoria, 3081, Australia|Royal Melbourne Hospital, Parkville, Victoria, 3050, Australia|Australian Alzheimer's Research Foundation, Nedlands, Western Australia, 6009, Australia|LKH - Universitaetsklinikum Graz, Graz, 8036, Austria|Christian-Doppler-Klinik - Universit?tsklinikum Salzburg, Salzburg, 5020, Austria|AKH - Medizinische Universit?t Wien, Vienna, 1090, Austria|AZ Klina, Brasschaat, 2930, Belgium|AZ Sint-Jan, Brugge, 8000, Belgium|Universitair Ziekenhuis Brussel, Brussel, 1090, Belgium|Universitair Ziekenhuis Gent, Gent, 9000, Belgium|AZ Groeninge, Kortrijk, 8500, Belgium|UZ Leuven, Leuven, 3000, Belgium|AZ Delta, Roeselare, 8800, Belgium|University of Calgary - Heritage Medical Research Clinic, Calgary, Alberta, T2N4Z6, Canada|The Medical Arts Health Research Group, Kamloops, British Columbia, V2C 5T1, Canada|The Medical Arts Health Research Group, Penticton, British Columbia, V2A 5L5, Canada|UBC Hospital, Vancouver, British Columbia, V6T 1Z3, Canada|Medical Arts Health Research Group, West Vancouver, British Columbia, V7T 1C5, Canada|True North Clinical Research - Halifax Inc., Halifax, Nova Scotia, B3S 1M7, Canada|True North Clinical Research, Kentville, Nova Scotia, MB3 2S7, Canada|St. Joseph's HC- Parkwood Institute, London, Ontario, N6C OA7, Canada|Bruyere Continuing Care, Ottawa, Ontario, K1N 5C8, Canada|Kawartha Centre - Redefining Healthy Aging, Peterborough, Ontario, K9H 2P4, Canada|Toronto Memory Program (Neurology Research Inc.), Toronto, Ontario, M3B 2S7, Canada|Toronto Sunnybrook Hospital, Toronto, Ontario, M4N 3M5, Canada|Toronto Western Hospital, Toronto, Ontario, M5T 2S8, Canada|Clinique de la Memoire de l'Outaouais, Gatineau, Quebec, J8T 8J1, Canada|Institut et Clinique MoCA, Greenfield Park, Quebec, J4V 2J2, Canada|Montreal Neurological Institute Clinical Research Unit, Montréal, Quebec, H3A 2B4, Canada|CHU de Quebec - H?pital de l' Enfant Jésus, Quebec, G1J 1Z4, Canada|CCBR - ?lborg - DK, Aalborg, 9000, Denmark|Danish Dementia Research Centre, K?benhavn, 2100, Denmark|CCBR - Vejle - DK, Vejle, 7100, Denmark|Terveystalo Ruoholahti, Helsinki, 00180, Finland|It?-Suomen yliopisto, Aivotutkimusyksikk?, Kuopio, 70210, Finland|CRST, Clinical Research Services Turku, Turku, 20520, Finland|CHU Strasbourg - H?pital Hautepierre, Strasbourg Cedex, Bas Rhin, 67098, France|H?pital de la Timone, Marseille cedex 05, Bouches-du-Rh?ne, 13385, France|Groupe Hospitalier Pellegrin - H?pital Pellegrin, Bordeaux Cedex, Gironde, 33076, France|Hopital Purpan, Toulouse cedex 9, Haute Garonne, 31059, France|H?pital La Grave, Toulouse Cedex 9, Haute Garonne, 31059, France|Hopital Gui de Chauliac, Montpellier, Herault, 34295, France|CHU Rennes - Pontchaillou, Rennes cedex 9, Ille Et Vilaine, 35033, France|CHU Nantes - Hopital Nord La?nnec, Nantes cedex 1, Loire Atlantique, 44093, France|CHU Reims - H?pital Maison Blanche, Reims, Marne, 51092, France|CHU Lille - Hopital Roger Salengro, Lille Cedex, Nord, 59037, France|H?pital Lariboisière, Paris cedex 10, Paris, 75010, France|CHU de Lyon - Hopital Neurologique Pierre Wertheimer, Bron Cedex, Rhone, 69677, France|H?pital des Chapennes, Villeurbanne, Rhone, 69100, France|Groupe Hospitalier Pitie-Salpetriere, Paris, 75013, France|H?pital Broca, Paris, 75013, France|Studienzentrum fur Neurologie und Psychiatrie, B?blingen, Baden Wuerttemberg, 71034, Germany|ISPG - Institut fuer Studien zur Psychischen Gesundheit, Mannheim, Baden Wuerttemberg, 68165, Germany|mind mvz GmbH, Stuttgart, Baden Wuerttemberg, 70182, Germany|Neuropoint Studienzentrum, Ulm, Baden Wuerttemberg, 89073, Germany|Universitaetsklinikum Ulm, Ulm, Baden Wuerttemberg, 89081, Germany|Klinikum Bayreuth GmbH- Hohe Warte, Bayreuth, Bayern, 95445, Germany|Bezirkskrankenhaus Guenzburg, Günzburg, Bayern, 89312, Germany|Klinikum rechts der Isar der TU Muenchen, Munich, Bayern, 81675, Germany|Institut fuer Schlaganfall- und Demenzforschung (ISD), München, Bayern, 81377, Germany|Neuropraxis Muenchen Sued, Unterhaching, Bayern, 82008, Germany|Neuro Centrum Science GmbH, Geschaftführende Gesellschafterin Barbara Unsorg und Prüfarzt Dr. med. G, Erbach, Hessen, 64711, Germany|Neurologische Gemeinschaftspraxis Kassel, Kassel, Hessen, 34121, Germany|Klinische Forschung Hannover-Mitte GmbH, Hannover, Niedersachsen, 30159, Germany|Universitaetsklinikum Aachen AOeR, Aachen, Nordrhein Westfalen, 52074, Germany|Neurozentrum Bielefeld, Bielefeld, Nordrhein Westfalen, 33647, Germany|Universitaetsklinikum Duesseldorf AoeR, Duesseldorf, Nordrhein Westfalen, 40225, Germany|Universitaetsklinikum Koeln, Koeln, Nordrhein Westfalen, 50937, Germany|Zentrum f. Neurologisch- Psychiatrische Studien und Begutachtung, Siegen, Nordrhein Westfalen, 57076, Germany|Klinikum Altenburger Land GmbH, Altenburg, Thueringen, 04600, Germany|Emovis GmbH, Berlin, 10629, Germany|Neurologie im Tempelhofer Hafen, Berlin, 12099, Germany|Charite Universitaetsmedizin Berlin - Campus Berlin Buch, Berlin, 13125, Germany|Ospedale degli Infermi, Ponderano, Biella, 13875, Italy|Azienda Ospedaliera Card. G. Panico, Tricase, Lecce, 73039, Italy|ASST di Monza, Monza, Milano, 20052, Italy|Fondazione Istituto G.Giglio di Cefalù, Cefalù, Palermo, 90015, Italy|Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (Presidio Spedali Civili), Brescia, 25123, Italy|Azienda Ospedaliero Universitaria San Martino, Genova, 16132, Italy|Ospedale San Raffaele, Milano, 20132, Italy|Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, 20133, Italy|AOU dell'Università degli studi della Campania Luigi Vanvitelli, Napoli, 80138, Italy|Azienda Ospedaliera e Universitaria di Perugia, Perugia, 06156, Italy|Azienda Ospedaliero Universitaria Pisana, Pisa, 56126, Italy|Azienda Ospedaliera Universitaria Policlinico Umberto I - Università di Roma La Sapienza, Roma, 00161, Italy|Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, 00168, Italy|Fondazione Santa Lucia IRCCS, Roma, 179, Italy|Azienda Ospedaliera Universitaria OO. RR. S. Giovanni di Dio e Ruggi D'Aragona, Salerno, 84131, Italy|A.O.U. Senese Policlinico Santa Maria alle Scotte, Siena, 53100, Italy|Research Site, Obu-shi, Aichi-Ken, 474-8511, Japan|Research Site, Chiba-shi, Chiba-Ken, 260-8656, Japan|Research Site, Chiba-shi, Chiba-Ken, 263-0043, Japan|Research Site, Inzai-shi, Chiba-Ken, 270-1694, Japan|Research Site, Toon-shi, Ehime-Ken, 791-0295, Japan|Research Site, Fukuoka-shi, Fukuoka-Ken, 814-0180, Japan|Research Site, Kurume-shi, Fukuoka-Ken, 830-0011, Japan|Research Site, Aizu-Wakamatsu, Fukushima-Ken, 965-8585, Japan|Research Site, Otake-shi, Hiroshima-Ken, 739-0696, Japan|Research Site, Asahikawa-shi, Hokkaido, 070-8644, Japan|Research Site, Sapporo-shi, Hokkaido, 064-8570, Japan|Research Site, Amagasaki-shi, Hyogo-Ken, 660-8511, Japan|Research Site, Himeji-shi, Hyogo-Ken, 670-0981, Japan|Research Site, Himeji-shi, Hyogo-Ken, 672-8043, Japan|Research Site, Kobe-shi, Hyogo-Ken, 650-0047, Japan|Research Site, Kita-gun, Kagawa-Ken, 761-0793, Japan|Research Site, Kamakura-shi, Kanagawa-Ken, 247-8533, Japan|Research Site, Kyoto-shi, Kyoto-Fu, 607-8113, Japan|Research Site, Kyoto-shi, Kyoto-Fu, 616-8255, Japan|Research Site, Tsu-shi, Mie-Ken, 514-8507, Japan|Research Site, Togitsu, Nagasaki-Ken, 851-2103, Japan|Research Site, Nagaoka-shi, Niigata-Ken, 940-2081, Japan|Research Site, Yufu-shi, Oita-Ken, 879-5593, Japan|Research Site, Kurashiki-shi, Okayama-Ken, 247-8533, Japan|Research Site, Okayama-shi, Okayama-Ken, 703-8265, Japan|Research Site, Tsukuba, Okayama-Ken, 701-0304, Japan|Research Site, Osaka-shi, Osaka-Fu, 545-8586, Japan|Research Site, Suita-shi, Osaka-Fu, 565-0871, Japan|Research Site, Iruma-gun, Saitama-Ken, 350-0495, Japan|Research Site, Kasukabe-shi, Saitama-Ken, 344-0036, Japan|Research Site, Shizuka-shi, Shizuoka-Ken, 424-8636, Japan|Research Site, Shizuoka-shi, Shizuoka-Ken, 420-8688, Japan|Research Site, Bunkyo-ku, Tokyo-To, 113-0034, Japan|Research Site, Kiyose-shi, Tokyo-To, 204-8585, Japan|Research Site, Kodaira-shi, Tokyo-To, 187-8551, Japan|Research Site, Yamagata-shi, Yamagata-Ken, 990-0834, Japan|Inha University Hospital, Incheon, Gyeonggi-do, 22332, Korea, Republic of|Seoul National University Bundang Hospital, Seongnam, Gyeonggi-do, 13620, Korea, Republic of|Gachon University Gil Medical Center, Incheon, 405-760, Korea, Republic of|Konkuk University Medical Center, Seoul, 05030, Korea, Republic of|Asan Medical Center, Seoul, 05505, Korea, Republic of|Samsung Medical Center, Seoul, 135-710, Korea, Republic of|Brain Research Center, Amsterdam, 1081 GN, Netherlands|Amphia Ziekenhuis, Molengracht, Breda, 4818 CK, Netherlands|Erasmus Medisch Centrum, Rotterdam, 3015 AA, Netherlands|Podlaskie Centrum Psychogeriatrii, Bialystok, 15-756, Poland|PALLMED Sp. z o.o., Bydgoszcz, 85-023, Poland|Klinika Psychiatrii Doroslych UCK, Gdansk, 80-952, Poland|Novo-Med Zielinski i wspolnicy Sp. j., Katowice, 40-650, Poland|SPZOZ Centralny Szpital Kliniczny UM w Lodzi, Lodz, 92-216, Poland|Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie, Lublin, 20-954, Poland|NZOZ "NEURO-KARD", "Ilkowski i Partnerzy" Sp. Partn. Lek., Poznan, 61-853, Poland|Neuro-Care Gabriela Klodowska, Siemianowice Slaskie, 41-100, Poland|Centrum Medyczne Senior, Sopot, 81-855, Poland|Osrodek Badan Klinicznych EUROMEDIS, Szczecin, 70-111, Poland|Centrum Medyczne NeuroProtect, Warszawa, 01-684, Poland|NZOZ Wroclawskie Centrum Alzheimerowskie, Wroclaw, 53659, Poland|Hospital de Braga, Braga, 4710-243, Portugal|Centro Hospitalar e Universitário de Coimbra E.P.E - Hospitais da Universidade de Coimbra, Coimbra, 3040-278, Portugal|Hospital Beatriz ?ngelo, Loures, 2674-514, Portugal|CNS-Campus Neurologico Senior, Torres Vedras, 2560-280, Portugal|Hospital General Universitario de Elche, Elche, Alicante, 03203, Spain|Hospital Universitario Reina Sofia, Cordoba, Córdoba, 14011, Spain|Policlinica Gipuzkoa, San Sebastian, Guipuzcoa, 20009, Spain|Clinica Universidad de Navarra, Pamplona, Navarra, 31008, Spain|CAE Oroitu, Getxo, Vizcaya, 48993, Spain|Hospital del Mar, Barcelona, 08003, Spain|Hospital de la Santa Creu i Sant Pau, Barcelona, 08025, Spain|Fundacio ACE, Barcelona, 08028, Spain|Hospital Clinic de Barcelona, Barcelona, 08036, Spain|Hospital Universitari de Santa Maria, Lleida, 25198, Spain|Complejo Hospitalario Ruber Juan Bravo, Madrid, 28006, Spain|Hospital Victoria Eugenia, Sevilla, 41009, Spain|Hospital Universitario Dr. Peset, Valencia, 46017, Spain|Hospital Universitari i Politecnic La Fe, Valencia, 46026, Spain|Sk?nes Universitetssjukhus, Malm?, 205 02, Sweden|Sahlgrenska Universitetssjukhuset, M?lndal Sjukhus, M?lndal, 205 02, Sweden|Karolinska Universitetssjukhuset, Huddinge, Stockholm, 141 86, Sweden|Akademiska Sjukhuset, Uppsala, 75185, Sweden|Spitalzentrum Biel, Biel/Bienne, 2501, Switzerland|H?pitaux Universitaires de Geneve- HUG, Genève, 1205, Switzerland|Centre Hospitalier Universitaire Vaudois, Lausanne, 1011, Switzerland|Ospedale Regionale di Lugano, Lugano, 6900, Switzerland|Institut fur Regenerative Medizin-IREM Universitat Zurich, Campus Schlieren, Schlieren, 8952, Switzerland|Changhua Christian Medical Foundation Changhua Christian Hospital, Changhua, 50004, Taiwan|Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, 833, Taiwan|National Cheng Kung University Hospital, Tainan, 704, Taiwan|Taipei Veterans General Hospital, Taipei, 11217, Taiwan|Chang Gung Memorial Hospital, Linkou, Taoyuan City, 333, Taiwan|Re:Cognition Health Ltd (London), London, Greater London, W1G 9JF, United Kingdom|Charing Cross Hospital, London, Greater London, W6 8RF, United Kingdom|The National Hospital for Neurology and Neurosurgery Centre, London, Greater London, WC1N 3BG, United Kingdom|Manchester Royal Infirmary, Manchester, Greater Manchester, M13 9WL, United Kingdom|The University of Edinburgh, Edinburgh, Lothian Region, EH10 5HF, United Kingdom|The RICE Centre, Bath, Somerset, BA1 3NG, United Kingdom|Queen Elizabeth University Hospital Campus, Glasgow, Strathclyde, G21 3UW, United Kingdom|Glasgow Memory Clinic Ltd, Motherwell, Strathclyde, ML1 4UF, United Kingdom|Ninewells Hospital, Dundee, Tayside Region, DD1 9SY, United Kingdom|Newcastle University, Newcastle upon Tyne, Tyne & Wear, NE4 5PL, United Kingdom Less << |
Tags: Aducanumab | BIIB037 | Amyloid-β/monoclonal antibody | Amyloid-β | Neuronal Signaling | Human Inhibitory Monoclonal Antibody | 1384260-65-4
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
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P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
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P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
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