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Chemical Structure| 1398496-82-6 Chemical Structure| 1398496-82-6

Structure of Afizagabar
CAS No.: 1398496-82-6

Chemical Structure| 1398496-82-6

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Afizagabar is a selective α5-GABAAR antagonist with IC50 and Ki values of 585 nM and 66 nM for α5β2γ2 and α5β3γ2 subtypes, respectively, primarily used in research to enhance hippocampal synaptic plasticity and cognitive function.

Synonyms: S44819; Egis-13529

4.5 *For Research Use Only !

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Product Details of Afizagabar

CAS No. :1398496-82-6
Formula : C19H12FN3O2S
M.W : 365.38
SMILES Code : O=C(N1)OC2=C1C=C3CC(C)=NN=C(C4=CC5=C(F)C=CC=C5S4)C3=C2
Synonyms :
S44819; Egis-13529
MDL No. :MFCD32899874

Safety of Afizagabar

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.74mL

0.55mL

0.27mL

13.68mL

2.74mL

1.37mL

27.37mL

5.47mL

2.74mL

 

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