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Chemical Structure| 141750-63-2 Chemical Structure| 141750-63-2

Structure of Pitavastatin lactone
CAS No.: 141750-63-2

Chemical Structure| 141750-63-2

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Pitavastatin lactone is the major metabolite of Pitavastatin in the human body. Pitavastatin is an effective competitive inhibitor of HMG-CoA reductase and undergoes minimal metabolism in liver microsomes.

Synonyms: Pivastatin lactone

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Product Details of Pitavastatin lactone

CAS No. :141750-63-2
Formula : C25H22FNO3
M.W : 403.45
SMILES Code : O=C1C[C@H](O)C[C@@H](/C=C/C2=C(C3=CC=C(F)C=C3)C4=CC=CC=C4N=C2C5CC5)O1
Synonyms :
Pivastatin lactone
MDL No. :MFCD09841193
InChI Key :XJVKVAFYQRWVAJ-MCBHFWOFSA-N
Pubchem ID :9801294

Safety of Pitavastatin lactone

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Biological Activity

Description
Pitavastatin lactone is a primary metabolite of Pitavastatin in humans. Pitavastatin serves as a potent competitive inhibitor of HMG-CoA reductase and undergoes minimal metabolism in hepatic microsomes [1].

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Bio Calculators
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1 mM

5 mM

10 mM

2.48mL

0.50mL

0.25mL

12.39mL

2.48mL

1.24mL

24.79mL

4.96mL

2.48mL

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