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Chemical Structure| 1418308-27-6 Chemical Structure| 1418308-27-6

Structure of EI1
CAS No.: 1418308-27-6

Chemical Structure| 1418308-27-6

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EI1 is a selective inhibitor of wild type EZH2 and EZH2 Y641F mutant with IC50 values of 15 nM and 13 nM, respectively.

Synonyms: KB-145943

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Product Details of EI1

CAS No. :1418308-27-6
Formula : C23H26N4O2
M.W : 390.48
SMILES Code : CCC(CC)N(C=C1)C2=C1C(C(NCC3=C(C)C=C(C)NC3=O)=O)=CC(C#N)=C2
Synonyms :
KB-145943
MDL No. :MFCD25976740
InChI Key :PFHDWRIVDDIFRP-UHFFFAOYSA-N
Pubchem ID :72199293

Safety of EI1

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Related Pathways of EI1

epigenetics

Isoform Comparison

Biological Activity

Target
  • Histone Methyltransferase

    Ezh2 (wild-type), IC50:15 nM

    EZH2 (Y641F), IC50:13 nM

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.56mL

0.51mL

0.26mL

12.80mL

2.56mL

1.28mL

25.61mL

5.12mL

2.56mL

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