Home Cart Sign in  
Chemical Structure| 142738-94-1 Chemical Structure| 142738-94-1

Structure of 142738-94-1

Chemical Structure| 142738-94-1

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 142738-94-1 ]

CAS No. :142738-94-1
Formula : C8H7F3O2
M.W : 192.14
SMILES Code : FC(F)(F)OC1=CC(OC)=CC=C1
MDL No. :MFCD01631504
InChI Key :OKSRAPDSZKICKZ-UHFFFAOYSA-N
Pubchem ID :2777188

Safety of [ 142738-94-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

Application In Synthesis of [ 142738-94-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 142738-94-1 ]

[ 142738-94-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 827-99-6 ]
  • [ 74-88-4 ]
  • [ 142738-94-1 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In water; ethyl acetate; N,N-dimethyl-formamide; at 0 - 20℃; for 13.5h; To a suspension of 20.0 g of <strong>[827-99-6]3-(trifluoromethoxy)phenol</strong> and 23.3 g of K2CO3 (anhydrous) in DMF (100 ml) was added 23.9 g of iodine methane under ice cooling, then the reaction mixture was warmed to room temperature, and was stirred at room temperature for 13 hours. To the reaction solution was added EtOAc (100 ml) and purified water (150 ml), and the resulting mixture was stirred for 30 minutes. After liquid separation, the aqueous layer was extracted with EtOAc (50 ml×2), the combined organic layer was washed with purified water (100 ml×3) and with saturated brine (50 ml) and dried overover MgSO4, then, the drying agent was separated by filtration, and the solvent was removed under reduced pressure to obtain 27.7 g of the title compound (crude form, yellow oil). The present compound was used in the next reaction without purification.MS (CI pos.) m/z: 193 ([M+H]+)1H-NMR (300 MHz, CDCl3) delta (ppm); 3.81 (s, 3H), 6.73-6.87 (m, 3H), 7.25-7.32 (m, 1H)
 

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 142738-94-1 ]

Fluorinated Building Blocks

Chemical Structure| 827-99-6

A258779 [827-99-6]

3-(Trifluoromethoxy)phenol

Similarity: 1.00

Chemical Structure| 1261752-88-8

A229081 [1261752-88-8]

3-Methoxy-5-(trifluoromethoxy)phenol

Similarity: 1.00

Chemical Structure| 828-27-3

A131146 [828-27-3]

4-(Trifluoromethoxy)phenol

Similarity: 0.96

Chemical Structure| 456-55-3

A346959 [456-55-3]

(Trifluoromethoxy)benzene

Similarity: 0.96

Chemical Structure| 710-18-9

A984225 [710-18-9]

1-Methoxy-4-(trifluoromethoxy)benzene

Similarity: 0.96

Aryls

Chemical Structure| 827-99-6

A258779 [827-99-6]

3-(Trifluoromethoxy)phenol

Similarity: 1.00

Chemical Structure| 1261752-88-8

A229081 [1261752-88-8]

3-Methoxy-5-(trifluoromethoxy)phenol

Similarity: 1.00

Chemical Structure| 828-27-3

A131146 [828-27-3]

4-(Trifluoromethoxy)phenol

Similarity: 0.96

Chemical Structure| 456-55-3

A346959 [456-55-3]

(Trifluoromethoxy)benzene

Similarity: 0.96

Chemical Structure| 710-18-9

A984225 [710-18-9]

1-Methoxy-4-(trifluoromethoxy)benzene

Similarity: 0.96

Ethers

Chemical Structure| 827-99-6

A258779 [827-99-6]

3-(Trifluoromethoxy)phenol

Similarity: 1.00

Chemical Structure| 1261752-88-8

A229081 [1261752-88-8]

3-Methoxy-5-(trifluoromethoxy)phenol

Similarity: 1.00

Chemical Structure| 828-27-3

A131146 [828-27-3]

4-(Trifluoromethoxy)phenol

Similarity: 0.96

Chemical Structure| 456-55-3

A346959 [456-55-3]

(Trifluoromethoxy)benzene

Similarity: 0.96

Chemical Structure| 710-18-9

A984225 [710-18-9]

1-Methoxy-4-(trifluoromethoxy)benzene

Similarity: 0.96

Trifluoromethyls

Chemical Structure| 827-99-6

A258779 [827-99-6]

3-(Trifluoromethoxy)phenol

Similarity: 1.00

Chemical Structure| 1261752-88-8

A229081 [1261752-88-8]

3-Methoxy-5-(trifluoromethoxy)phenol

Similarity: 1.00

Chemical Structure| 828-27-3

A131146 [828-27-3]

4-(Trifluoromethoxy)phenol

Similarity: 0.96

Chemical Structure| 456-55-3

A346959 [456-55-3]

(Trifluoromethoxy)benzene

Similarity: 0.96

Chemical Structure| 710-18-9

A984225 [710-18-9]

1-Methoxy-4-(trifluoromethoxy)benzene

Similarity: 0.96