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Chemical Structure| 1454908-27-0 Chemical Structure| 1454908-27-0

Structure of 1454908-27-0

Chemical Structure| 1454908-27-0

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Product Details of [ 1454908-27-0 ]

CAS No. :1454908-27-0
Formula : C10H14ClN3O2
M.W : 243.69
SMILES Code : O=C(OC(C)(C)C)NCC1=NN=C(Cl)C=C1

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Application In Synthesis of [ 1454908-27-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1454908-27-0 ]

[ 1454908-27-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 871826-15-2 ]
  • [ 24424-99-5 ]
  • [ 1454908-27-0 ]
YieldReaction ConditionsOperation in experiment
460 mg With sodium hydrogencarbonate; In tetrahydrofuran; water; at 20.0℃; for 2.0h; To a solution of <strong>[871826-15-2](6-chloropyridazin-3-yl)methanamine</strong> (300 mg, 2.0 mmol) in a mixture of THF (9 mL) and water (9 mL), was added NaHCO3 (200 mg, 2.4 mmol) and (Boc)2O (570 mg, 2.6 mmol). The mixture was stirred at 20 C for 2 h, and then the reaction mixture was concentrated to remove the THF. The water was extracted with DCM (2x), and the combined organic layers were dried over sodium sulfate, filtered, and concentrated to give The organic solvent was dried with anhydrous Na2SO4, concentrated by reduce pressure to give tert-butyl ((6-chloropyridazin-3- yl)methyl)carbamate (460 mg).
 

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