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[ CAS No. 1460-34-0 ]

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Cat. No.: {[proInfo.prAm]}
2D
Chemical Structure| 1460-34-0
Chemical Structure| 1460-34-0
Structure of 1460-34-0 *Storage: {[proInfo.prStorage]}

Quality Control of [ 1460-34-0 ]

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Alternatived Products of [ 1460-34-0 ]

Product Details of [ 1460-34-0 ]

CAS No. :1460-34-0MDL No. :MFCD00002582
Formula : C6H10O3 Boiling Point : 190.5°C at 760 mmHg
Linear Structure Formula :-InChI Key :-
M.W :130.14Pubchem ID :-
Synonyms :

Computed Properties of [ 1460-34-0 ]

TPSA : - H-Bond Acceptor Count : -
XLogP3 : - H-Bond Donor Count : -
SP3 : - Rotatable Bond Count : -

Safety of [ 1460-34-0 ]

Signal Word:WarningClass:N/A
Precautionary Statements:P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313UN#:N/A
Hazard Statements:H315-H319Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 1460-34-0 ]

  • Downstream synthetic route of [ 1460-34-0 ]

[ 1460-34-0 ] Synthesis Path-Downstream   1~6

  • 1
  • [ 1460-34-0 ]
  • [ 949-90-6 ]
  • [ 113586-15-5 ]
  • 3
  • [ 1460-34-0 ]
  • [ 319-78-8 ]
  • [ 51576-04-6 ]
  • 4
  • [ 1460-34-0 ]
  • [ 1509-35-9 ]
YieldReaction ConditionsOperation in experiment
With meso-2,6-D-diaminopimelic acid dehydrogenase mutant BC621; ammonium chloride; NADPH In various solvent(s) for 24h;
  • 5
  • [ 1460-34-0 ]
  • [ 4649-12-1 ]
  • N-(2-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethyl)-3-methyl-2-oxopentanamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
72% With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 75℃; for 0.333333h;Microwave irradiation; Inert atmosphere; General procedure: To a mixture of -keto carboxylic acid (1.5 equiv), EDC·HCl (1.5 equiv), HOBt (1.5 equiv) and DIPEA (2.0 equiv) in DMF (c = 0.1 M) was added the appropriate amine (1.0 equiv) and reaction was conducted under microwave irradiation at 75 C, and 25 W for 20 min (Discover system, CEM Corporation/ USA). Afterwards saturated aqueous NaHCO3 was added and extracted three times with EtOAc. The combined organic layers were dried over MgSO4, concentrated and purified by flash chromatography (Biotage/ Sweden, SNAP KP-Sil, 10 g, EtOAc in n-hexane or MeOH in DCM as eluent).
  • 6
  • [ 1460-34-0 ]
  • [ 27404-31-5 ]
  • N-(2-(benzofuran-3-yl)ethyl)-3-methyl-2-oxopentanamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
54% With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 75℃; for 0.333333h;Microwave irradiation; Inert atmosphere; General procedure: To a mixture of -keto carboxylic acid (1.5 equiv), EDC·HCl (1.5 equiv), HOBt (1.5 equiv) and DIPEA (2.0 equiv) in DMF (c = 0.1 M) was added the appropriate amine (1.0 equiv) and reaction was conducted under microwave irradiation at 75 C, and 25 W for 20 min (Discover system, CEM Corporation/ USA). Afterwards saturated aqueous NaHCO3 was added and extracted three times with EtOAc. The combined organic layers were dried over MgSO4, concentrated and purified by flash chromatography (Biotage/ Sweden, SNAP KP-Sil, 10 g, EtOAc in n-hexane or MeOH in DCM as eluent).
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