Alternatived Products of [ 1460-34-0 ]
Product Details of [ 1460-34-0 ]
CAS No. : | 1460-34-0 |
MDL No. : | MFCD00002582 |
Formula : |
C6H10O3
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
130.14
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Pubchem ID : | - |
Synonyms : |
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Application In Synthesis of [ 1460-34-0 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 1460-34-0 ]
- 1
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[ 1460-34-0 ]
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[ 949-90-6 ]
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[ 113586-15-5 ]
- 2
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[ 1460-34-0 ]
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[ 319-78-8 ]
- 3
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[ 1460-34-0 ]
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[ 319-78-8 ]
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[ 51576-04-6 ]
- 4
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[ 1460-34-0 ]
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[ 1509-35-9 ]
Yield | Reaction Conditions | Operation in experiment |
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With meso-2,6-D-diaminopimelic acid dehydrogenase mutant BC621; ammonium chloride; NADPH In various solvent(s) for 24h; |
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- 5
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[ 1460-34-0 ]
-
[ 624-41-9 ]
Yield | Reaction Conditions | Operation in experiment |
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Multi-step reaction with 3 steps
1: α-ketoisovalerate decarboxylase / 30 °C / Enzymatic reaction
2: NADPH / 30 °C / Enzymatic reaction
3: alcohol O-acyltransferase-1 / 30 °C / Enzymatic reaction |
|
- 6
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[ 1460-34-0 ]
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[ 4649-12-1 ]
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N-(2-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethyl)-3-methyl-2-oxopentanamide
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
72% |
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 75℃; for 0.333333h;Microwave irradiation; Inert atmosphere; |
General procedure: To a mixture of -keto carboxylic acid (1.5 equiv), EDC·HCl (1.5 equiv), HOBt (1.5 equiv) and DIPEA (2.0 equiv) in DMF (c = 0.1 M) was added the appropriate amine (1.0 equiv) and reaction was conducted under microwave irradiation at 75 C, and 25 W for 20 min (Discover system, CEM Corporation/ USA). Afterwards saturated aqueous NaHCO3 was added and extracted three times with EtOAc. The combined organic layers were dried over MgSO4, concentrated and purified by flash chromatography (Biotage/ Sweden, SNAP KP-Sil, 10 g, EtOAc in n-hexane or MeOH in DCM as eluent). |
- 7
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[ 1460-34-0 ]
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[ 27404-31-5 ]
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N-(2-(benzofuran-3-yl)ethyl)-3-methyl-2-oxopentanamide
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
54% |
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 75℃; for 0.333333h;Microwave irradiation; Inert atmosphere; |
General procedure: To a mixture of -keto carboxylic acid (1.5 equiv), EDC·HCl (1.5 equiv), HOBt (1.5 equiv) and DIPEA (2.0 equiv) in DMF (c = 0.1 M) was added the appropriate amine (1.0 equiv) and reaction was conducted under microwave irradiation at 75 C, and 25 W for 20 min (Discover system, CEM Corporation/ USA). Afterwards saturated aqueous NaHCO3 was added and extracted three times with EtOAc. The combined organic layers were dried over MgSO4, concentrated and purified by flash chromatography (Biotage/ Sweden, SNAP KP-Sil, 10 g, EtOAc in n-hexane or MeOH in DCM as eluent). |