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Chemical Structure| 1518800-35-5 Chemical Structure| 1518800-35-5

Structure of Afabicin
CAS No.: 1518800-35-5

Chemical Structure| 1518800-35-5

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Afabicin is the prodrug of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci.

Synonyms: Debio 1450; AFN-1720

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Product Details of Afabicin

CAS No. :1518800-35-5
Formula : C23H24N3O7P
M.W : 485.43
SMILES Code : O=C(N(C)CC1=C(C)C2=CC=CC=C2O1)/C=C/C3=CC(CC4)=C(N=C3)N(COP(O)(O)=O)C4=O
Synonyms :
Debio 1450; AFN-1720
MDL No. :N/A

Safety of Afabicin

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT03723551 Bone or Joint Infection Phase 2 Not yet recruiting November 1, 2019 United States, Florida ... More >> Midland Florida Clinical Research Center Not yet recruiting DeLand, Florida, United States, 32720 Ukraine Cherkasy Regional Hospital of Cherkasy Oblast Council Not yet recruiting Cherkasy, Ukraine, 18009 Dnipropetrovsk Regional Clinical Hospital Not yet recruiting Dnipropetrovs'k, Ukraine, 49027 Ukrainian State Institute of Medical and Social Problems of Disability Ministry of Public Health of Ukraine Not yet recruiting Dnipropetrovs'k, Ukraine, 49027 Kharkiv City Clinical Hospital #2 Not yet recruiting Kharkiv, Ukraine, 61037 Institute of Traumatology and Orthopedics Not yet recruiting Kyiv, Ukraine, 01601 Kyiv Regional Clinical Hospital Not yet recruiting Kyiv, Ukraine, 04107 Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.06mL

0.41mL

0.21mL

10.30mL

2.06mL

1.03mL

20.60mL

4.12mL

2.06mL

 

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