Home Cart 0 Sign in  

[ CAS No. 153587-01-0 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 153587-01-0
Chemical Structure| 153587-01-0
Structure of 153587-01-0 * Storage: {[proInfo.prStorage]}

Quality Control of [ 153587-01-0 ]

Related Doc. of [ 153587-01-0 ]

SDS
Alternatived Products of [ 153587-01-0 ]
Alternatived Products of [ 153587-01-0 ]

Product Details of [ 153587-01-0 ]

CAS No. :153587-01-0 MDL No. :MFCD00928190
Formula : C15H8F6N2O2 Boiling Point : -
Linear Structure Formula :- InChI Key :N/A
M.W :362.23 g/mol Pubchem ID :4552
Synonyms :

1. NS-1619

Safety of [ 153587-01-0 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 153587-01-0 ]

  • Downstream synthetic route of [ 153587-01-0 ]

[ 153587-01-0 ] Synthesis Path-Downstream   1~7

  • 1
  • [ 159117-83-6 ]
  • [ 10294-33-4 ]
  • 1-(2-Hydroxy-5-trifluoromethylphenyl)-5-trifluoromethyl-1,3-dihydro-2H-benzimidazol-2-thione [ No CAS ]
  • [ 153587-01-0 ]
YieldReaction ConditionsOperation in experiment
In dichloromethane; EXAMPLE 6 1-(2-Hydroxy-5-trifluoromethylphenyl)-5-trifluoromethyl-1,3-dihydro-2H-benzimidazol-2-one. A suspension of 1-(2-Methoxy-5-trifluoromethylphenyl)-5-trifluoromethyl-1,3-dihydro-2H-benzimidazol-2-one (70 mmol, 26.3 g) in absolute methylenechloride is added borontribromide (84 mmol, 7.94 ml). After stirring at room temperature for four hours the reaction mixture is poured into water and the title compoundcompound is collected by filtration as white crystals, M.p. 228-231C. The following compound is prepared in a similar manner. 1-(2-Hydroxy-5-trifluoromethylphenyl)-5-trifluoromethyl-1,3-dihydro-2H-benzimidazol-2-thione, M.p. decompose at 160C.
In dichloromethane; EXAMPLE 6 1-(2-Hydroxy-5-trifluoromethylphenyl)-5-trifluoromethyl-1,3-dihydro-2H-benzimidazol-2-one. A suspension of 1-(2-Methoxy-5-trifluoromethylphenyl)-5-trifluoromethyl-1,3-dihydro-2H-benzimidazol-2-one (70 mmol, 26.3 g) in absolute methylenechloride is added borontribromide (84 mmol, 7.94 ml). After stirring at room temperature for four hours the reaction mixture is poured into water and the title compoundcompound is collected by filtration as white crystals, M.p. 228-231 C. The following compound is prepared in a similar manner. 1-(2-Hydroxy-5-trifluoromethylphenyl)-5-trifluoromethyl-1,3-dihydro-2H-benzimidazol-2-thione, M.p. decompose at 160 C.
  • 2
  • methylenechloride+methanol [ No CAS ]
  • [ 153587-01-0 ]
  • 5-trifluoromethyl-2,3-dihydro-1-(3-nitro-5-trifluoromethyl-2-hydroxyphenyl)-1H-2-oxo-benzimidazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
With potassium nitrate; In sulfuric acid; EXAMPLE 7 1-(2-Hydroxy-3-nitro-5-trifluoromethylphenyl)-5-trifluoromethyl-1,3-dihydro-2H-benzimidazol-2-one. To an ice cooled solution of 1-(2-Hydroxy-5-trifluoromethylphenyl)-5-trifluoromethyl-1,3-dihydro-2H-benzimidazol-2-one (1.38 mmol, 0.50 g) in concentrated sulphuric acid (6 ml) is added an ice cooled solution of potassium nitrate (1.38 mmol, 0.14 g) in concentrated sulphuric acid (8 ml). The reaction mixture is allowed to reach room temperature and is poured into ice. The crude product is collected by filtration and subjected to column chromatography using methylenechloride+methanol (9+1) as eluent. The fractions containing the product are concentrated in vacuo yielding the title compound as slightly yellow crystals, M.p.>360 C.
  • 3
  • [ 75-09-2 ]
  • [ 153587-01-0 ]
  • 5-trifluoromethyl-2,3-dihydro-1-(3-nitro-5-trifluoromethyl-2-hydroxyphenyl)-1H-2-oxo-benzimidazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
With potassium nitrate; In methanol; sulfuric acid; EXAMPLE 7 1-(2-Hydroxy-3-nitro-5-trifluoromethylphenyl)-5-trifluoromethyl- 1,3-dihydro-2H-benzimidazol-2-one. To an ice cooled solution of 1-(2-Hydroxy-5-trifluoromethylphenyl)-5-trifluoromethyl-1,3-dihydro-2H-benzimidazol-2-one (1.38 mmol, 0.50 g) in concentrated sulphuric acid (6 ml) is added an ice cooled solution of potassium nitrate (1.38 mmol, 0.14 g) in concentrated sulphuric acid (8 ml). The reaction mixture is allowed to reach room temperature and is poured into ice. The crude product is collected by filtration and subjected to column chromatography using methylenechloride + methanol (9+1) as eluent. The fractions containing the product are concentrated in vacuo yielding the title compound as slightly yellow crystals, M.p. >360C.
  • 4
  • N-(2-methoxy-5-trifluoromethylphenyl)-2-nitro-4-trifluoromethyl aniline [ No CAS ]
  • [ 153587-01-0 ]
  • 5
  • [ 146812-90-0 ]
  • [ 153587-01-0 ]
  • 6
  • [ 394-25-2 ]
  • [ 153587-01-0 ]
  • 7
  • [ 349-65-5 ]
  • [ 153587-01-0 ]
Historical Records