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Chemical Structure| 154257-75-7 Chemical Structure| 154257-75-7
Chemical Structure| 154257-75-7

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Product Details of 3-Chloro-2,4-difluorobenzoic acid

CAS No. :154257-75-7
Formula : C7H3ClF2O2
M.W : 192.55
SMILES Code : O=C(O)C1=CC=C(F)C(Cl)=C1F
MDL No. :MFCD01631387
Boiling Point : No data available
InChI Key :YGYZTZAEZMCPSC-UHFFFAOYSA-N
Pubchem ID :2773532

Safety of 3-Chloro-2,4-difluorobenzoic acid

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of 3-Chloro-2,4-difluorobenzoic acid

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 154257-75-7 ]

[ 154257-75-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 124-38-9 ]
  • [ 38361-37-4 ]
  • [ 154257-75-7 ]
  • 2
  • [ 887267-38-1 ]
  • [ 154257-75-7 ]
YieldReaction ConditionsOperation in experiment
35.5 g With sulfuric acid; at 100 - 120℃; In a 500 mL four-necked flask, 250 mL of 20% (by mass concentration) dilute sulfuric acid was poured,33.8 g of <strong>[887267-38-1]3-chloro-2,4-difluorobenzonitrile</strong> obtained in the step (5) was added portionwise with stirring,Keeping the reaction until the content of <strong>[887267-38-1]3-chloro-2,4-difluorobenzonitrile</strong> is less than or equal to 2% at 100 to 120 DEG C;(7) The oil layer in the solution obtained in step (6) was extracted with 150 mL of toluene,Separate the oil layer,Wash the oil layer with cold water 2 to 3 times,Cooling to about 0 overnight,A yellowish powdery solid precipitated, which was filtered off and dried, yielding 35.5 g of 3-chloro-2,4-difluorobenzoic acid as a pale yellow powder.
 

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