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Chemical Structure| 158021-47-7 Chemical Structure| 158021-47-7

Structure of α-Galactosylceramide
CAS No.: 158021-47-7

Chemical Structure| 158021-47-7

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α-Galactosylceramide (KRN7000) is a synthetic glycolipid with antitumor and immunostimulatory effects, acting as a potent NKT cell agonist that binds effectively to CD1d。

Synonyms: KRN7000; α-GalCer

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Product Details of α-Galactosylceramide

CAS No. :158021-47-7
Formula : C50H99NO9
M.W : 858.32
SMILES Code : CCCCCCCCCCCCCCCCCCCCCCCCCC(N[C@@H](CO[C@@H]1[C@@H]([C@H]([C@H]([C@@H](CO)O1)O)O)O)[C@H](O)[C@H](O)CCCCCCCCCCCCCC)=O
Synonyms :
KRN7000; α-GalCer
MDL No. :MFCD00939559

Safety of α-Galactosylceramide

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00363155 Hepatitis B, Chronic PHASE1|PHASE2 COMPLETED 2025-07-06 Erasmus MC, University Medical... More >> Center Rotterdam, Rotterdam, 3015GD, Netherlands Less <<
NCT00352235 Chronic Hepatitis C PHASE1|PHASE2 COMPLETED 2025-05-05 Erasmus MC, Rotterdam, 3000CA,... More >> Netherlands Less <<
NCT00003985 Lung Cancer|Unspecified Adult ... More >>Solid Tumor, Protocol Specific Less << PHASE1 WITHDRAWN - Innsbruck Universitaetsklinik,... More >> Innsbruck, A-6020, Austria|Kaiser Franz Josef Hospital, Vienna, A-1100, Austria|Institut Jules Bordet, Brussels, 1000, Belgium|Ludwig Institute for Cancer Research-Brussels Branch, Brussels, B-1200, Belgium|Universitair Ziekenhuis Antwerpen, Edegem, B-2650, Belgium|U.Z. Gasthuisberg, Leuven, B-3000, Belgium|Herlev Hospital - University Hospital of Copenhagen, Herlev, DK-2730, Denmark|Centre Jean Perrin, Clermont-Ferrand, 63011, France|Centre Leon Berard, Lyon, 69373, France|CRLCC Nantes - Atlantique, Nantes-Saint Herblain, 44805, France|Institut Claudius Regaud, Toulouse, 31052, France|Institut Gustave Roussy, Villejuif, F-94805, France|Universitaetsklinik und Strahlenklinik - Essen, Essen, D-45122, Germany|Klinikum Nurnberg, Nuremberg (Nurnberg), D-90419, Germany|Antoni van Leeuwenhoekhuis, Amsterdam, 1066 CX, Netherlands|Academisch Ziekenhuis der Vrije Universiteit, Amsterdam, 1117 MB, Netherlands|Academisch Ziekenhuis Groningen, Groningen, 9713 EZ, Netherlands|University Medical Center Nijmegen, Nijmegen, NL-6252 HB, Netherlands|Rotterdam Cancer Institute, Rotterdam, 3075 EA, Netherlands|Norwegian Radium Hospital, Oslo, N-0310, Norway|University Hospital, Basel, CH-4031, Switzerland|Inselspital, Bern, Bern, CH-3010, Switzerland|Kantonsspital - Saint Gallen, Saint Gallen, CH-9007, Switzerland|Newcastle General Hospital, Newcastle Upon Tyne, England, NE4 6BE, United Kingdom|Ninewells Hospital and Medical School, Dundee, Scotland, DD1 9SY, United Kingdom|Western General Hospital, Edinburgh, Scotland, EH4 9NQ, United Kingdom|C.R.C. Beatson Laboratories, Glasgow, Scotland, G61 1BD, United Kingdom Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.17mL

0.23mL

0.12mL

5.83mL

1.17mL

0.58mL

11.65mL

2.33mL

1.17mL

 

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