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Chemical Structure| 1597426-52-2 Chemical Structure| 1597426-52-2

Structure of T-448 free base
CAS No.: 1597426-52-2

Chemical Structure| 1597426-52-2

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T-448 free base is a specific, orally active and irreversible inhibitor of lysine-specific demethylase 1 (LSD1, an H3K4 demethylase), with an IC50 of 22 nM. T-448 free base enhances H3K4 methylation in primary cultured rat neurons[1].

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Product Details of T-448 free base

CAS No. :1597426-52-2
Formula : C17H20N4OS
M.W : 328.43
SMILES Code : O=C(NC1=NN=C(C)S1)C2=CC=CC([C@H]3[C@H](NC4CCC4)C3)=C2
MDL No. :MFCD34469355

Safety of T-448 free base

Related Pathways of T-448 free base

epigenetics

Isoform Comparison

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Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.04mL

0.61mL

0.30mL

15.22mL

3.04mL

1.52mL

30.45mL

6.09mL

3.04mL

 

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