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Chemical Structure| 1613509-49-1 Chemical Structure| 1613509-49-1

Structure of SRI-41315
CAS No.: 1613509-49-1

Chemical Structure| 1613509-49-1

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SRI-41315 induces prolonged stalling of stop codons, inhibiting premature termination codons (PTCs) associated with cystic fibrosis and restoring CFTR protein expression and function. By reducing the abundance of termination factor eRF1 while enhancing aminoglycoside-mediated readthrough, SRI-41315 significantly increases CFTR activity.

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Product Details of SRI-41315

CAS No. :1613509-49-1
Formula : C22H19N3O2
M.W : 357.41
SMILES Code : O=C1N(C2=CC=CC=C2)C(C3CCC3)=NC(N(C)C4=C5C=CC=C4)=C1C5=O
MDL No. :N/A

Safety of SRI-41315

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

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10 mM

2.80mL

0.56mL

0.28mL

13.99mL

2.80mL

1.40mL

27.98mL

5.60mL

2.80mL

 

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