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Chemical Structure| 1624602-30-7 Chemical Structure| 1624602-30-7

Structure of VR23
CAS No.: 1624602-30-7

Chemical Structure| 1624602-30-7

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VR23 is a small molecule inhibitor which targets β2 of the 20S proteasome with IC50 of 1 nM and can induce apoptosis of cancer cells via cyclin E–mediated centrosome amplification.

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Product Details of VR23

CAS No. :1624602-30-7
Formula : C19H16ClN5O6S
M.W : 477.88
SMILES Code : O=S(N1CCN(C2=CC=NC3=CC(Cl)=CC=C23)CC1)(C4=CC=C([N+]([O-])=O)C=C4[N+]([O-])=O)=O
MDL No. :MFCD28502093
InChI Key :PDQVZPPIHADUOO-UHFFFAOYSA-N
Pubchem ID :73442847

Safety of VR23

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Isoform Comparison

Biological Activity

Target
  • Proteasome

    Trypsin-like proteasomes, IC50:1 nM

    Chymotrypsin-like proteasomes, IC50:3 μM

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.09mL

0.42mL

0.21mL

10.46mL

2.09mL

1.05mL

20.93mL

4.19mL

2.09mL

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