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Chemical Structure| 1785666-59-2 Chemical Structure| 1785666-59-2

Structure of CP-465022 HCl
CAS No.: 1785666-59-2

Chemical Structure| 1785666-59-2

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CP-465022 HCl is a potent, selective, and non-competitive AMPA receptor antagonist with anticonvulsant activity, IC50 of 25 nM.

Synonyms: CP-465022 hydrochloride

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Product Details of CP-465022 HCl

CAS No. :1785666-59-2
Formula : C26H25Cl2FN4O
M.W : 499.41
SMILES Code : O=C1C2C=C(C=CC=2N=C(/C=C/C2C=CC=C(CN(CC)CC)N=2)N1C1C(Cl)=CC=CC=1)F.[H]Cl
Synonyms :
CP-465022 hydrochloride
MDL No. :MFCD12828745
InChI Key :YKYDGCRJPYLXHY-GVYCEHEKSA-N
Pubchem ID :53251536

Safety of CP-465022 HCl

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Description
CP-465022 hydrochloride stands as a selective, potent, noncompetitive antagonist of AMPA receptors with anticonvulsant properties. It is effective against the Kainate-induced response in rat cortical neurons with an IC50 of 25 nM, offering a new instrument for the exploration of AMPA receptors' roles in both normal and abnormal physiological processes[1].[2].

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