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Chemical Structure| 1818427-07-4 Chemical Structure| 1818427-07-4

Structure of CDK8/19-IN-1
CAS No.: 1818427-07-4

Chemical Structure| 1818427-07-4

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CDK8/19-IN-1 is a potent, selective and oral bioavailable CDK8/19 dual inhibitor, with IC50s of 0.46 nM, 0.99 nM and 270 nM for CDK8, CDK19 and CDK9, respectively.

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Product Details of CDK8/19-IN-1

CAS No. :1818427-07-4
Formula : C19H18N4O4S2
M.W : 430.50
SMILES Code : O=C(C1=C2CCC3=C(SN=C3)C2=C(OC4=CC=C(C(NCCOC)=O)N=C4)S1)N
MDL No. :MFCD31692369

Safety of CDK8/19-IN-1

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of CDK8/19-IN-1

Hedgehog

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.32mL

0.46mL

0.23mL

11.61mL

2.32mL

1.16mL

23.23mL

4.65mL

2.32mL

 

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