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Chemical Structure| 1887095-82-0 Chemical Structure| 1887095-82-0

Structure of RapaLink-1
CAS No.: 1887095-82-0

Chemical Structure| 1887095-82-0

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RapaLink-1 is the third-generation mTOR inhibitor exploiting the unique juxtaposition of two drug (first- and second-generation mTOR kinase inhibitors) –binding pockets to create a bivalent interaction that allows inhibition of the mutants which has resistance to the previous TORKi (mTOR kinase inhibitors).

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Product Details of RapaLink-1

CAS No. :1887095-82-0
Formula : C91H138N12O24
M.W : 1784.14
SMILES Code : NC1=C2C(C3=CC=C4OC(N)=NC4=C3)=NN(CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN5N=NC(COCCO[C@@H]6CC[C@@H](C[C@@H](C)[C@@]7(CC([C@H](C)/C=C(C)/[C@@H](O)[C@@H](OC)C([C@H](C)C[C@H](C)/C=C/C=C\C=C(C)\[C@@H](OC)C[C@@]8(CC[C@@H](C)[C@@](C(C(N9CCCC[C@]9(C(O7)=O)[H])=O)=O)(O)O8)[H])=O)=O)[H])C[C@H]6OC)=C5)=O)C2=NC=N1
MDL No. :MFCD32633594

Safety of RapaLink-1

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of RapaLink-1

PI3K-AKT

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

0.56mL

0.11mL

0.06mL

2.80mL

0.56mL

0.28mL

5.60mL

1.12mL

0.56mL

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