Structure of Natalizumab
CAS No.: 189261-10-7
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Natalizumab is a humanized IgG4 monoclonal antibody that prevents ITGA4 from binding to its ligand. Natalizumab has potential for multiple sclerosis and Crohn's disease research.
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Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
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CAS No. : | 189261-10-7 |
M.W : | 146.22 kDa |
SMILES Code : | NONE |
GHS Pictogram: |
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Signal Word: | Warning |
Hazard Statements: | H302-H315-H319 |
Precautionary Statements: | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT00297232 | Relapsing-Remitting Multiple S... More >>clerosis Less << | PHASE3 | TERMINATED | 2025-04-14 | Research Site, Camperdown, 205... More >>0, Australia|Research Site, Heidelberg, 3084, Australia|Research Site, Parkville, 3050, Australia|Research Site, Brugge, 8000, Belgium|Research Site, Brussels, 1070, Belgium|Research Site, Charleroi, 6000, Belgium|Research Site, Diepenbeek, 3590, Belgium|Research Site, Melsbroek, 1820, Belgium|Research Site, Sijsele, 8340, Belgium|Research Site, Vancouver, British Columbia, V6T 2B5, Canada|Research Site, Halifax, Nova Scotia, B3H IV7, Canada|Research Site, Kingston, Ontario, K7L 2V7, Canada|Research Site, London, Ontario, N6A5A5, Canada|Research Site, New York, Ontario, M4N 3M5, Canada|Research Site, Ottawa, Ontario, K2G6E2, Canada|Research Site, Toronto, Ontario, M5B 1W8, Canada|Research Site, Gatineau, Quebec, J8Y 1W7, Canada|Research Site, Greenfield Park, Quebec, J4V 2H1, Canada|Research Site, Montreal, Quebec, H3A2B4, Canada|Research Site, Brno, 625 00, Czech Republic|Research Site, Brno, 656 91, Czech Republic|Research Site, Hradec Kralove, 500 05, Czech Republic|Research Site, Olomouc, 775 20, Czech Republic|Research Site, Ostrava, 708 52, Czech Republic|Research Site, Pardubice, 532 03, Czech Republic|Research Site, Plzen, 323 00, Czech Republic|Research Site, Praha 2, 12000, Czech Republic|Research Site, Praha 5, 150 06, Czech Republic|Research Site, Aarhus C, 8000, Denmark|Research Site, Esbjerg, 6700, Denmark|Research Site, Kobenhavn, 2100, Denmark|Research Site, Helsinki, 00290, Finland|Research Site, Tampere, 33520, Finland|Research Site, Turku, 20100, Finland|Research Site, Besancon, 25030, France|Research Site, Bordeaux, 33076, France|Research Site, Clermont-Ferrand, 63003, France|Research Site, Creteil, 94101, France|Research Site, Dijon, 21033, France|Research Site, Lille, 59037, France|Research Site, Lyon, 69677, France|Research Site, Marseille, 13385, France|Research Site, Nancy, 54035, France|Research Site, Paris, 75019, France|Research Site, Paris, 75651, France|Research Site, Rennes, 35033, France|Research Site, Strasbourg, 67091, France|Research Site, Toulouse, 31059, France|Research Site, Berlin, 13347, Germany|Research Site, Essen, 45122, Germany|Research Site, Gie?en, 35385, Germany|Research Site, Hannover, 30625, Germany|Research Site, Hennigsdorf, 16761, Germany|Research Site, München, 81377, Germany|Research Site, Offenbach, 63069, Germany|Research Site, Osnabrück, 49076, Germany|Research Site, Regensburg, 93053, Germany|Research Site, Rostock, 18147, Germany|Research Site, Athens, 11527, Greece|Research Site, Budapest, 1021, Hungary|Research Site, Budapest, 1115, Hungary|Research Site, Budapest, 1145, Hungary|Research Site, Budapest, 1204, Hungary|Research Site, Debrecen, 4012, Hungary|Research Site, Debrecen, 4031, Hungary|Research Site, Gyor, 9000, Hungary|Research Site, Nyiregyhaza, 4400, Hungary|Research Site, Szekesfehervar, 8000, Hungary|Research Site, Dublin, 4, Ireland|Research Site, Jerusalem, 91120, Israel|Research Site, Tel Hashomer, 52621, Israel|Research Site, Bari, 70124, Italy|Research Site, Genova, 16132, Italy|Research Site, Milano, 20132, Italy|Research Site, Roma, 00185, Italy|Research Site, Amsterdam, 1081HV, Netherlands|Research Site, Breda, 4818 CK, Netherlands|Research Site, Hertogenbosch, 5211 NL, Netherlands|Research Site, Nieuwegein, 3435 CM, Netherlands|Research Site, Nijmegen, 6533 PA, Netherlands|Research Site, Rotterdam, 3015 GD, Netherlands|Research Site, Auckland, 1023, New Zealand|Research Site, Christchurch, 8011, New Zealand|Research Site, Bia?ystok, 15-402, Poland|Research Site, Bia?ystok, 15-420, Poland|Research Site, Bydgoszcz, 85-681, Poland|Research Site, Gdańsk, 80-803, Poland|Research Site, Katowice, 40-752, Poland|Research Site, Kraków, 31-530, Poland|Research Site, Lodz, 90-153, Poland|Research Site, Lublin, 20-954, Poland|Research Site, Warsaw, 02-957, Poland|Research Site, Warszawa, 02-097, Poland|Research Site, Barcelona, 08035, Spain|Research Site, Barcelona, 08907, Spain|Research Site, Málaga, 29010, Spain|Research Site, Goteborg, 41685, Sweden|Research Site, Stockholm, 141 86, Sweden|Research Site, Stockholm, 17176, Sweden|Research Site, Basel, 4031, Switzerland|Research Site, Ankara, 06100, Turkey|Research Site, Istanbul, 34303, Turkey|Research Site, Istanbul, 34390, Turkey|Research Site, Essex, RM7 0AG, United Kingdom|Research Site, Liverpool, L9 7AJ, United Kingdom|Research Site, London, E1 1BB, United Kingdom|Research Site, London, SE5 9RF, United Kingdom|Research Site, London, SW17 0QT, United Kingdom|Research Site, Newcastle Upon Tyne, NE14LP, United Kingdom|Research Site, Oxford, OX3 9DU, United Kingdom|Research Site, Sheffield, S10 2JF, United Kingdom|Research Site, Stoke on Trent, ST4 7LN, United Kingdom Less << |
NCT05701423 | Multiple Sclerosis | TERMINATED | 2024-07-31 | Klinik für Neurologie, Univers... More >>it?tsklinikum Düsseldorf, Düsseldorf, 40225, Germany Less << | |
NCT02483845 | Inclusion Body Myositis (IBM) | PHASE1 | UNKNOWN | 2025-11-17 | Phoenix Neurological Insitutut... More >>e, Phoenix, Arizona, 85018, United States Less << |
NCT03046251 | Multiple Sclerosis | PHASE4 | COMPLETED | 2025-12-23 | SUNY Buffalo, Buffalo, New Yor... More >>k, 14203, United States Less << |
NCT05265728 | Multiple Sclerosis, Relapsing-... More >>Remitting Less << | PHASE3 | TERMINATED | 2024-05-27 | Juntendo University Hospital, ... More >>Bunkyo-ku, 113-8431, Japan|Chiba University Hospital, Chiba-shi, 260-8677, Japan|St.Marianna University Hospital, Kawasaki-shi, 216-8511, Japan|National Center of Neurology and Psychiatry, Kodaira-shi, 187-8551, Japan|Kansai Medical University Medical Center, Moriguchi-shi, 570-8507, Japan|Tokyo Metropolitan Hospital Organization Tokyo Metropolitan Ebara Hospital, Ota-ku, 145-0065, Japan|The Kitasato Institute Kitasato University Hospital, Sagamihara-shi, 252-0375, Japan|National Hospital Organization Hokkaido Medical Center, Sapporo-shi, 063-0005, Japan|Tohoku Medical and Pharmaceutical University Hospital, Sendai-shi, 983-8512, Japan|Osaka University Hospital, Suita-shi, 565-0871, Japan|University of Tsukuba Hospital, Tsukuba-shi, 305-8576, Japan|Tokyo Women's Medical University Yachiyo Medical Center, Yachiyo-shi, 276-8524, Japan Less << |
NCT04832399 | Relapsing Remitting Multiple S... More >>clerosis Less << | COMPLETED | 2023-10-02 | Research Site, Amadora, 2720-2... More >>76, Portugal|Research Site, Angra do Heroismo, 9700-049, Portugal|Research Site, Aveiro, 3810-164, Portugal|Research Site, Braga, 4710-243, Portugal|Research Site, Coimbra, 3004-561, Portugal|Research Site, Faro, 8000-386, Portugal|Research Site, Funchal, 9000-177, Portugal|Research Site, Guimaraes, 4835-044, Portugal|Research Site, Leiria, 2410-197, Portugal|Research Site, Lisboa, 1649-028, Portugal|Research Site, Loures, 2674-514, Portugal|Research Site, Matosinhos, 4450-021, Portugal|Research Site, Penafiel, 4564-007, Portugal|Research Site, Porto, 4200-319, Portugal|Research Site, Santa Maria da Feira, 4520-220, Portugal|Research Site, Setubal, 2910-446, Portugal|Research Site, Viana do Castelo, 4904-858, Portugal|Research Site, Vila Nova de Gaia, 4434-502, Portugal Less << | |
NCT04964700 | Multiple Sclerosis | UNKNOWN | 2022-06-01 | Multiple Sclerosis Center of N... More >>ortheastern New York, P.C., Latham, New York, 12110, United States Less << | |
NCT00276172 | Multiple Sclerosis | PHASE3 | COMPLETED | 2025-01-06 | Performed at only C-1801, C-18... More >>02, and C-1803 sites globally. No general public enrollment. Biogen Idec is located in, Cambridge, Massachusetts, 02142, United States Less << |
NCT00744679 | Multiple Sclerosis | PHASE4 | COMPLETED | 2025-12-08 | Research Site, Latham, New Yor... More >>k, United States Less << |
NCT05304520 | Relapsing-Remitting Multiple S... More >>clerosis (RRMS) Less << | COMPLETED | 2024-04-30 | Neurozentrum am K?nigsplatz Au... More >>gsburg; Dres. Müller und Schmid, Augsburg, Germany|Praxis Dr. Sch?ll, Bad Homburg, Germany|Caritas Krankenhaus Bad Mergentheim, Bad Mergentheim, Germany|Neurologische Praxis Dr. med. Boris-Alexander Kallmann, Bamberg, Germany|Marianne-Strau?-Klinik Starnberg, Berg, Germany|Neurologie am Mexikoplatz, Berlin, Germany|Neurologie im Tempelhofer Hafen Berlin, Berlin, Germany|Neurologisches Facharztzentrum Dr. Masri & Kollegen, Berlin, Germany|NFZB Neurologisches Facharztzentrum Berlin, Berlin, Germany|Praxis für Neurologie/Dr. med. Martin Delf, Berlin, Germany|Katholisches Klinikum Bochum gGmbH, Bochum, Germany|Praxis Dres. Kausch/Lippert, Bogen, Germany|Neurologische Studiengesellschaft Bonn GbR, Bonn, Germany|MVZ Daun GmbH, Daun, Germany|Neurologie Dillingen, Dillingen, Germany|Gemeinschaftspraxis für Neurologie, Düsseldorf, Germany|Praxis Dr. Hartmann, Eltville, Germany|Neuro Centrum science GmbH, Erbach, Germany|Universit?tsklinikum Erlangen, Neurolische Klinik, Erlangen, Germany|med.ring GmbH, Essen, Germany|NeuroDot GmbH, Grevenbroich, Germany|GP Dr. med. Wolfgang Klostermann/ Dr. med. Samir Al-Boutros, Hagen, Germany|Krankenhaus Martha-Maria Halle-D?lau; Klinik für Neurologie, Halle (Saale), Germany|Universit?tsklinikum Jena, Hans-Berger-Klinik für Neurologie, Jena, Germany|Praxis Dr. Fischer, Lappersdorf, Germany|Neurokomm - Gesellschaft für Studien und Kommunikation, Mannheim, Germany|NPS Neurologisch Psychiatrische Studiengesellschaft, Mannheim, Germany|GP Neurologie am Preu?enmuseum/ Martina Lorenz/ Dr. med. Birgit Erker, Minden, Germany|Landesklinkum Mistelbach-G?nserndorf, Abteilung Neurologie, Mistelbach, Germany|Hygieia Pharmakologisches Studienzentrum Chemnitz GmbH, Au?enstelle Mittweida, Mittweida, Germany|Amperklinikum München Haar, München, Germany|CODAST, München, Germany|Neurologie Neu-Ulm, Neu-Ulm, Germany|Bergmann.Consult, Neuburg, Germany|Neurozentrum Prien, Prien am Chiemsee, Germany|EMSA, Singen, Germany|NeuroSinsheim, Sinsheim, Germany|Nervenfach?rztliche GP, Ulm, Germany|Neuropraxis München Süd, Unterhaching, Germany|Praxis Dr. Krause, Wolfratshausen, Germany Less << | |
NCT05236777 | Multiple Sclerosis | RECRUITING | 2025-04-30 | Fakultní nemocnice Brno, Brno,... More >> Czechia|Fakultní nemocnice u sv. Anny v Brně, Brno, Czechia|Fakultní nemocnice Hradec Králové, Hradec Králové, Czechia|Nemocnice Jihlava, Jihlava, Czechia|Fakultní nemocnice Olomouc, Olomouc, Czechia|Fakultní nemocnice v Ostravě, Ostrava, Czechia|Nemocnice Pardubického kraje, Pardubice, Czechia|Fakultní nemocnice v Plzni, Pilsen, Czechia|Fakultní nemocnice Královské Vinohrady v Praze, Prague, Czechia|Fakultní nemocniceMotol v Praze, Prague, Czechia|Fakultní Thomayerova nemocnice v Praze v Kr?i, Prague, Czechia|V?eobecná fakultní nemocnice v Praze, Prague, Czechia|Nemocnice Teplice, Teplice, Czechia|Krajská nemocnice T. Bati ve Zlíně, Zlín, Czechia|Nemocnice ?eské Budějovice, ?eské Budějovice, Czechia Less << | |
NCT00942214 | Multiple Sclerosis | PHASE4 | COMPLETED | 2025-03-11 | service de neurologie, h?pital... More >> Purpan, Toulouse, 31059, France Less << |
NCT05532163 | Multiple Sclerosis, Relapsing-... More >>Remitting Less << | PHASE4 | TERMINATED | 2023-10-09 | Neurologische Praxis Dr. med. ... More >>Boris-Alexander Kallmann, Bamberg, 96052, Germany|Neurologische Studiengesellschaft Bonn GbR, Bonn, 53111, Germany Less << |
NCT05925049 | Multiple Sclerosis | ACTIVE_NOT_RECRUITING | 2025-12-31 | Research Site, Cambridge, Mass... More >>achusetts, 02142, United States Less << | |
NCT01077466 | Primary Progressive Multiple S... More >>clerosis|Secondary Progressive Multiple Sclerosis Less << | PHASE2 | COMPLETED | 2025-01-12 | Danish Multiple Sclerosis Cent... More >>er, Section 2082, Rigshospitalet, Copenhagen, 2100, Denmark Less << |
NCT03811886 | Pulmonary Metastatic Osteosarc... More >>oma (pOS) Less << | PHASE1|PHASE2 | WITHDRAWN | 2026-10-01 | University Hospitals Cleveland... More >> Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, 44106, United States Less << |
NCT03516526 | Multiple Sclerosis | PHASE4 | COMPLETED | 2019-07-01 | OLVG, Amsterdam, Netherlands|V... More >>U medical center, Amsterdam, Netherlands|Rijnstate Hospital, Arnhem, Netherlands|Erasmus medical center, Rotterdam, Netherlands|St. Antonius Hospital, Utrecht, Netherlands Less << |
Tags: Natalizumab | Integrin | Integrin/monoclonal antibody | Exosome | Cytoskeleton | Cancer Stem Cells | Human Inhibitory Monoclonal Antibody | 189261-10-7
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
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