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Chemical Structure| 204067-01-6 Chemical Structure| 204067-01-6

Structure of PD176252
CAS No.: 204067-01-6

Chemical Structure| 204067-01-6

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PD176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17 nM and 1 nM for human BB1 and BB2 receptors, and 0.66 nM, 16 nM for Rat BB1 and BB2 receptors, respectively; also an agonist of N-Formyl peptide receptor1/2 (FPR1/FPR2), with EC50s of 0.31 and 0.66 μM in HL-60 cells.

Synonyms: PD176252

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Product Details of PD176252

CAS No. :204067-01-6
Formula : C32H36N6O5
M.W : 584.67
SMILES Code : O=C(NCC1(C2=NC=C(OC)C=C2)CCCCC1)[C@](NC(NC3=CC=C([N+]([O-])=O)C=C3)=O)(C)CC4=CNC5=C4C=CC=C5
Synonyms :
PD176252
MDL No. :MFCD09971099

Safety of PD176252

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of PD176252

GPCR

Isoform Comparison

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1.71mL

0.34mL

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8.55mL

1.71mL

0.86mL

17.10mL

3.42mL

1.71mL

 

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