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Chemical Structure| 210627-03-5 Chemical Structure| 210627-03-5

Structure of 210627-03-5

Chemical Structure| 210627-03-5

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Product Details of [ 210627-03-5 ]

CAS No. :210627-03-5
Formula : C11H11N3O2
M.W : 217.22
SMILES Code : O=C(C1=C(C)ON=C1)NC2=CC=C(N)C=C2
MDL No. :MFCD09043173

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Application In Synthesis of [ 210627-03-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 210627-03-5 ]

[ 210627-03-5 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 42831-50-5 ]
  • [ 106-50-3 ]
  • [ 210627-03-5 ]
YieldReaction ConditionsOperation in experiment
In tetrahydrofuran; acetic acid; Stage a) 5-Methylisoxazole-4-carboxylic acid (4-aminophenyl)amide 10.1 g (0.08 mol) of <strong>[42831-50-5]5-methylisoxazole-4-carboxylic acid</strong> and 8.65 g (0.08 mol) of p-phenylenediamine are dissolved in 300 ml of tetrahydrofuran and 18.05 g (0.088 mol) of dicyclohexyicarbodiimide are added. After 5 hours ("h"), the deposited precipitate is filtered off with suction, the organic phase is concentrated and the product is chromatographed on silica gel by means of ethyl acetate/petroleum ether with addition of 1% glacial acetic acid and then crystallized from ethyl acetate/petroleum ether. The yield of the process was 6.8 g of acetate salt with a melting point of 123 C. to 128 C.
  • 2
  • [ 42831-50-5 ]
  • [ 210627-03-5 ]
 

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