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Chemical Structure| 21919-05-1 Chemical Structure| 21919-05-1

Structure of Tretazicar
CAS No.: 21919-05-1

Chemical Structure| 21919-05-1

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CB 1954 is an anticancer prodrug used in gene therapy research and is activated by NAD(P)H Quinone Oxidoreductase 2.

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Product Details of Tretazicar

CAS No. :21919-05-1
Formula : C9H8N4O5
M.W : 252.18
SMILES Code : O=C(N)C1=CC(N2CC2)=C([N+]([O-])=O)C=C1[N+]([O-])=O
InChI Key :WOCXQMCIOTUMJV-UHFFFAOYSA-N
Pubchem ID :89105

Safety of Tretazicar

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Related Pathways of Tretazicar

DNA

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00746590 Hepatocellular Carcinoma Phase 2 Terminated(Study terminated pr... More >>ematurely by sponsor for business reason. One patient was enrolled.) Less << - Belgium ... More >> Cliniques Universitaires Saint-Luc Brussels, Belgium, 1200 Less <<
NCT00746590 - Terminated(Study terminated pr... More >>ematurely by sponsor for business reason. One patient was enrolled.) Less << - -

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.97mL

0.79mL

0.40mL

19.83mL

3.97mL

1.98mL

39.65mL

7.93mL

3.97mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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