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Chemical Structure| 2244881-69-2 Chemical Structure| 2244881-69-2

Structure of STING-IN-3
CAS No.: 2244881-69-2

Chemical Structure| 2244881-69-2

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STING-IN-3 is a STING inhibitor that blocks the STING signaling pathway by targeting the transmembrane cysteine residue of STING, suitable for research on immune-related diseases.

Synonyms: C-171

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Product Details of STING-IN-3

CAS No. :2244881-69-2
Formula : C17H20N2O4
M.W : 316.35
SMILES Code : O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(CCCCCC)C=C2
Synonyms :
C-171

Safety of STING-IN-3

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Isoform Comparison

Biological Activity

Description
STING-IN-3 serves as an inhibitor of stimulator of interferon genes (STING) by efficiently inhibiting both hsSTING and mmSTING through covalent targeting of the predicted transmembrane cysteine residue 91, thereby blocking activation-induced palmitoylation of STING [1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.16mL

0.63mL

0.32mL

15.81mL

3.16mL

1.58mL

31.61mL

6.32mL

3.16mL

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