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There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 2306193-61-1 Chemical Structure| 2306193-61-1

Structure of VZ185
CAS No.: 2306193-61-1

Chemical Structure| 2306193-61-1

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VZ185 is a potent, fast, and selective VHL based dual degrader probe of BRD9 and BRD7 with DC50s of 4.5 and 1.8 nM, respectively. VZ185 is cytotoxic in EOL-1 and A-402 cells, with EC50s of 3 nM and 40 nM, respectively.

4.5 *For Research Use Only !

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Product Details of VZ185

CAS No. :2306193-61-1
Formula : C53H67FN8O8S
M.W : 995.21
SMILES Code : CN1C(C2=CN=CC=C2C(C3=CC(OC)=C(CN4CCN(CCCCCOC5=C(CNC([C@@H]6C[C@@H](O)CN6C([C@@H](NC(C7(F)CC7)=O)C(C)(C)C)=O)=O)C=CC(C8=C(C)N=CS8)=C5)CC4)C(OC)=C3)=C1)=O
MDL No. :MFCD32689447

Safety of VZ185

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501
Class:8
UN#:3261
Packing Group:

Related Pathways of VZ185

epigenetics

Isoform Comparison

Protocol

Bio Calculators
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5.02mL

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10.05mL

2.01mL

1.00mL

 

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