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Chemical Structure| 2334525-50-5 Chemical Structure| 2334525-50-5

Structure of TD-428
CAS No.: 2334525-50-5

Chemical Structure| 2334525-50-5

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TD-428 is a PROTAC targeting on pan-BET with DC50 of 0.32nM for BRD4, consist of BET inhibitor, JQ1, as a warhead linked to CRBN modulator TD-106 as the E3 ligase ligand.

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Product Details of TD-428

CAS No. :2334525-50-5
Formula : C43H43ClN10O7S
M.W : 879.38
SMILES Code : CC1=C(C)C(C(C2=CC=C(Cl)C=C2)=N[C@@H](CC(NC3=CC(OCCOCCOCCNC4=C(C(N(C5CCC(NC5=O)=O)N=N6)=O)C6=CC=C4)=CC=C3)=O)C7=NN=C(C)N78)=C8S1
MDL No. :N/A

Safety of TD-428

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epigenetics

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1 mM

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1.14mL

0.23mL

0.11mL

5.69mL

1.14mL

0.57mL

11.37mL

2.27mL

1.14mL

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