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[ CAS No. 23635-14-5 ]

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Cat. No.: {[proInfo.prAm]}
2D
Chemical Structure| 23635-14-5
Chemical Structure| 23635-14-5
Structure of 23635-14-5 *Storage: {[proInfo.prStorage]}

Quality Control of [ 23635-14-5 ]

Related Doc. of [ 23635-14-5 ]

SDS

Product Details of [ 23635-14-5 ]

CAS No. :23635-14-5MDL No. :MFCD00062539
Formula : C10H14O2 Boiling Point : 284.9°C at 760 mmHg
Linear Structure Formula :-InChI Key :CC(=C)[C@H]1CCC(=CC1)C(O)=O
M.W :166.22Pubchem ID :2724160
Synonyms :

Computed Properties of [ 23635-14-5 ]

TPSA : - H-Bond Acceptor Count : -
XLogP3 : - H-Bond Donor Count : -
SP3 : - Rotatable Bond Count : -

Safety of [ 23635-14-5 ]

Signal Word:WarningClassN/A
Precautionary Statements:P261-P264-P271-P280-P302 P352-P304 P340 P312-P305 P351 P338-P332 P313-P337 P313-P362-P403 P233-P405-P501UN#:N/A
Hazard Statements:H315-H319-H335Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 23635-14-5 ]

  • Downstream synthetic route of [ 23635-14-5 ]

[ 23635-14-5 ] Synthesis Path-Downstream   1~10

  • 1
  • [ 3017-69-4 ]
  • [ 23635-14-5 ]
  • 2-methyl-1-propenyl (S)-perillate [ No CAS ]
  • 3
  • [ 23635-14-5 ]
  • [ 54288-70-9 ]
  • (S)-(4-bromopiperidin-1-yl)(4-(prop-1-en-2-yl)cyclohex-1-en-1-yl)methanone [ No CAS ]
YieldReaction ConditionsOperation in experiment
83% With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20℃; for 18h;Inert atmosphere; General procedure: To a stirring solution of 4-bromopiperidinium hydrobromide bromide (1.0 equiv), EDC (1.5 equiv) andDMAP (10 mol %) in anhydrous CH2Cl2 (0.50 M) under an atmosphere of nitrogen was added N,Ndiisopropylethylamine(2.0 equiv). The corresponding carboxylic acid (1.0-1.1 equiv) in CH2Cl2 (to 2.0M of limiting reagent) was added dropwise to the above solution over 5 minutes. The mixture wasstirred at room temperature for 18 h. Then, the mixture was concentrated in vacuo and suspended inaqueous 1 M NaOH (5.0 mL/mmol) and extracted with EtOAc (3 × 5.0 mL/mmol). The organicextracts were combined and washed with 1 M HCl (5.0 mL/mmol), brine (5.0 mL/mmol), dried overNa2SO4 and concentrated in vacuo. The residue was purified by column chromatography under theconditions noted to yield the desired product.
Reference: [1]Chem,2020
  • 4
  • [ 23635-14-5 ]
  • [ 54288-70-9 ]
  • (S)-(4-(3-methyl-2-(pyridin-2-yl)phenyl)piperidin-1-yl)(4-(prop-1-en-2-yl)cyclohex-1-en-1-yl)methanone [ No CAS ]
Reference: [1]Chem,2020
  • 5
  • [ 23635-14-5 ]
  • C18H24O6 [ No CAS ]
  • 6
  • [ 23635-14-5 ]
  • C10H15FO2 [ No CAS ]
  • C10H15FO2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With HO4S(1-)*K(1+)*13FH; In 1,2-dichloro-ethane; at 0 - 20℃; for 2h; General procedure: Conditions B. An 8-mL PTFE vial fitted with a stirring bar was charged with dry DCE (0.6 mL) and alkene starting material (0.2 mmol). The mixture was cooled down to 0 C. KHSO4-13HF (27 muL, 0.5 equiv, 6.5 equiv based on HF) was then added in one portion at rt. The progress of reaction was monitored by TLC (visualized by KMnO4 stain). Product usually showed a little higher polarity than the starting material on TLC (Rf difference<0.1). The reaction was then cooled down to 0 C. and quenched by CaCO3. The resulting mixture was then stirred at room temperature and filtered through kieselguhr. The filtrate was concentrated and the residue was purified with flash chromatography.; Isomer Ratio: (6:1) 1H NMR (400 MHz, CDCl3) delta 7.10 (s, 1H), 7.00 (s, 0.16H), 2.51 (d, J=19.3 Hz, 1H), 2.44-2.29 (m, 1.6H), 2.23-2.11 (m, 1.1H), 2.01 (dd, J=35.6, 15.0 Hz, 2.2H), 1.87 (m, 0.2H), 1.82-1.70 (m, 1H), 1.33 (dd, J=21.9, 3.5 Hz, 6H), 1.25 (dd, J=12.2, 7.0 Hz, 1H), 1.04 (t, J=9.2 Hz, 0.19H), 1.01-0.91 (m, 1H). (0145) 13C NMR (100 MHz, CDCl3) delta 172.99, 172.45, 155.86, 139.48, 138.60, 136.92, 130.32, 127.26, 126.54, 123.89, 116.44, 115.89, 35.16, 34.31, 34.24, 28.04, 25.58, 25.50, 23.66, 21.31, 21.00, 20.80. (0146) 19F NMR (376 MHz, CDCl3) delta -141.17--142.90 (m, 1F), -160.86--161.76 (m, 0.16F). (0147) HRMS: (ESI+) [M+H] cal. for C10H16FO2: 187.1134; found: 187.1132.
  • 7
  • [ 23635-14-5 ]
  • C19H20N2O [ No CAS ]
  • 8
  • [ 23635-14-5 ]
  • C26H22N2O3 [ No CAS ]
  • 9
  • [ 23635-14-5 ]
  • C25H22N2O [ No CAS ]
  • 10
  • [ 23635-14-5 ]
  • [ 106-99-0 ]
  • (6S)-6-(prop-1-en-2-yl)-3-vinyl-3,4,5,6,7,8-hexahydro-1H-isochromen-1-one [ No CAS ]
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