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Chemical Structure| 2366260-33-3 Chemical Structure| 2366260-33-3

Structure of Tubulin inhibitor 11
CAS No.: 2366260-33-3

Chemical Structure| 2366260-33-3

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Tubulin inhibitor 11 is an orally active microtubule protein (tubulin) inhibitor that targets the colchicine-binding site on tubulin, inhibiting microtubule polymerization and promoting mitotic arrest and apoptosis。

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Product Details of Tubulin inhibitor 11

CAS No. :2366260-33-3
Formula : C22H23N3O3S
M.W : 409.50
SMILES Code : O=C(NCC1=CC=C(C)N=C1)C2=CC=C(C)C(NS(=O)(C3=CC=C(C)C=C3)=O)=C2
MDL No. :N/A

Safety of Tubulin inhibitor 11

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of Tubulin inhibitor 11

cytoskeleton

Isoform Comparison

Biological Activity

Description
Tubulin inhibitor 11 is a potent and orally active inhibitor of tubulin. It targets the Colchicine binding site on tubulin, inhibits tubulin polymerization, induces mitotic blockade, and promotes apoptosis [1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.44mL

0.49mL

0.24mL

12.21mL

2.44mL

1.22mL

24.42mL

4.88mL

2.44mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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