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Chemical Structure| 2375070-79-2 Chemical Structure| 2375070-79-2

Structure of MS48107
CAS No.: 2375070-79-2

Chemical Structure| 2375070-79-2

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MS48107 is an effective selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68). It shows high selectivity for GPR68 over related proton GPCRs, neurotransmitter transporters, and hERG ion channels, and easily crosses the blood-brain barrier (BBB) in mice.

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Product Details of MS48107

CAS No. :2375070-79-2
Formula : C23H20FN5O2
M.W : 417.44
SMILES Code : OCC1=CC=CC(F)=C1C2=NC(N)=NC(NCC3=CC=C(OC4=CC=CC=C4)C=C3)=N2
MDL No. :N/A

Safety of MS48107

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Related Pathways of MS48107

GPCR

Isoform Comparison

Biological Activity

Description
MS48107 is a potent and selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68). It shows selectivity for GPR68 over closely related proton GPCRs, neurotransmitter transporters, and hERG ion channels. MS48107 can effectively cross the blood-brain barrier (BBB) in mice[1].

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Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.40mL

0.48mL

0.24mL

11.98mL

2.40mL

1.20mL

23.96mL

4.79mL

2.40mL

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