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Chemical Structure| 2403703-30-8 Chemical Structure| 2403703-30-8

Structure of Zurletrectinib
CAS No.: 2403703-30-8

Chemical Structure| 2403703-30-8

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Synonyms: ICP-723

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Product Details of Zurletrectinib

CAS No. :2403703-30-8
Formula : C19H19F2N7O2
M.W : 415.40
SMILES Code : F[C@H]1C[C@@]2([H])N(C1)C3=NC4=C(NC(NC[C@@H](OC5=NC=C(F)C=C52)C)=O)C=NN4C=C3
Synonyms :
ICP-723

Safety of Zurletrectinib

Related Pathways of Zurletrectinib

RTK

Isoform Comparison

Biological Activity

In Vitro:

Cell Line
Concentration Treated Time Description References
IRC and KM12 cells 1-5000 nM 72 hours To assess the effect of Selpercatinib on the growth inhibition and TRK-mediated signaling in NTRK fusion-positive tumor cells. Results showed that Selpercatinib significantly inhibited tumor cell growth and TRK signaling. PMC11300601

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.41mL

0.48mL

0.24mL

12.04mL

2.41mL

1.20mL

24.07mL

4.81mL

2.41mL

 

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