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Chemical Structure| 2408648-20-2 Chemical Structure| 2408648-20-2

Structure of BO-264
CAS No.: 2408648-20-2

Chemical Structure| 2408648-20-2

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BO-264 is a highly TACC3 inhibitor with IC50 value of 188nM. It significantly decreased centrosomal TACC3 during both mitosis and interphase, as well as displayed potent anti-proliferative activity (~90% have less than 1μM GI50 value) in the NCI-60 cell line panel compromising nine different cancer types.

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Product Details of BO-264

CAS No. :2408648-20-2
Formula : C18H19N5O3
M.W : 353.38
SMILES Code : COC1=CC=C(C2=NOC(NC3=NC(N4CCOCC4)=NC=C3)=C2)C=C1
MDL No. :MFCD32671323
InChI Key :WRCGBYNVBFVRTN-UHFFFAOYSA-N
Pubchem ID :146018837

Safety of BO-264

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Target
  • FGFR3

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.83mL

0.57mL

0.28mL

14.15mL

2.83mL

1.41mL

28.30mL

5.66mL

2.83mL

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