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Chemical Structure| 2408840-26-4 Chemical Structure| 2408840-26-4

Structure of Imlunestrant
CAS No.: 2408840-26-4

Chemical Structure| 2408840-26-4

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Imlunestrant is an orally effective, selective estrogen receptor (ER) degrader (SERD) with pure antagonistic properties. Imlunestrant can persistently inhibit ER-dependent gene transcription and cell growth, suitable for research on ER-positive (ER+) advanced breast cancer (aBC) and endometrial carcinoma (EEC).

Synonyms: LY-3484356

4.5 *For Research Use Only !

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Product Details of Imlunestrant

CAS No. :2408840-26-4
Formula : C29H24F4N2O3
M.W : 524.51
SMILES Code : OC1=CC=C2C([C@@H](C3=CC=C(OCCN4CC(CF)C4)C=C3)OC5=C6C=CC(C(F)(F)F)=C5)=C6C=NC2=C1
Synonyms :
LY-3484356
MDL No. :MFCD34789380

Safety of Imlunestrant

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT05440344 Hepatic Insufficiency|Healthy PHASE1 COMPLETED 2024-02-28 Inland Empire Liver Foundation... More >>, Rialto, California, 92377, United States|Orlando Clinical Research Center, Orlando, Florida, 32809, United States|American Research Corporation at Texas Liver Institute, San Antonio, Texas, 78215, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.91mL

0.38mL

0.19mL

9.53mL

1.91mL

0.95mL

19.07mL

3.81mL

1.91mL

 

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