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Chemical Structure| 251577-09-0 Chemical Structure| 251577-09-0

Structure of FTI-2148
CAS No.: 251577-09-0

Chemical Structure| 251577-09-0

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FTI-2148 is a RAS C-terminal mimetic dual farnesyl transferase (FT-1) and geranylgeranyl transferase-1 (GGT-1) inhibitor with IC50s of 1.4 nM and 1.7 μM for FT-1 and GGT-1, respectively.

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Product Details of FTI-2148

CAS No. :251577-09-0
Formula : C24H28N4O3S
M.W : 452.57
SMILES Code : CSCC[C@@H](C(O)=O)NC(C1=CC=C(CNCC2=CN=CN2)C=C1C3=CC=CC=C3C)=O
MDL No. :MFCD08056245

Safety of FTI-2148

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1 mM

5 mM

10 mM

2.21mL

0.44mL

0.22mL

11.05mL

2.21mL

1.10mL

22.10mL

4.42mL

2.21mL

 

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