Structure of Eribulin
CAS No.: 253128-41-5
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Eribulin, a synthetic analogue of halichondrin B used for breast cancer, binds to tubulin and microtubules.
Synonyms: ER-086526; E7389; B1939
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CAS No. : | 253128-41-5 |
Formula : | C40H59NO11 |
M.W : | 729.90 |
SMILES Code : | C=C1C[C@@](CC[C@@]2(C[C@@]3([H])O4)O[C@]([C@](O[C@](C5)([H])CC6)([H])[C@@]6([H])O7)([H])[C@@]4([H])[C@]7([H])[C@@]3([H])O2)([H])O[C@@]1([H])CC[C@](C[C@@H](C)C8=C)([H])O[C@]8([H])C[C@@](O[C@H](C[C@H](O)CN)[C@@H]9OC)([H])[C@]9([H])CC5=O |
Synonyms : |
ER-086526; E7389; B1939
|
MDL No. : | MFCD23160037 |
GHS Pictogram: |
![]() |
Signal Word: | Warning |
Hazard Statements: | H302-H315-H319-H335 |
Precautionary Statements: | P261-P305+P351+P338 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT00097721 | Breast Neoplasms | PHASE2 | COMPLETED | 2025-11-06 | Jonesboro, Arkansas, United St... More >>ates|Deer Park, California, United States|La Verne, California, United States|Pasadena, California, United States|Pomona, California, United States|Brooksville, Florida, United States|New Port Richey, Florida, United States|Plantation, Florida, United States|New Orleans, Louisiana, United States|Southaven, Mississippi, United States|Missoula, Montana, United States|Syracuse, New York, United States|Middletown, Ohio, United States|Memphis, Tennessee, United States|Amarillo, Texas, United States|Richardson, Texas, United States Less << |
NCT01669252 | Breast Cancer | PHASE2 | COMPLETED | 2025-06-15 | Institut Gustave Roussy, Ville... More >>juif, 94800, France|Klinikum des Landkreises Deggendorf Frauenklinik Mammazentrum, Deggendorf, 94469, Germany|Brustzentrum im Krankenhaus K?ln-Holweide Priv. Doz., K?ln, 51067, Germany|Brustzentrum der Universit?t München, Munic, 81377, Germany|Klinikum Südstadt Rostock, Universit?tsfrauenklinik und Poliklinik, Rostock, 18059, Germany|Instituto Portugues de Oncologia de Coimbra Francisco Gentil, EPE, Coimbra, 3001-651, Portugal|Hospital da Luz, Lisboa, 1500-650, Portugal|Instituto Portugues de Oncologia de Porto Francisco Gentil, EPE, Porto, 4200-072, Portugal|Hospital de la Santa Creu i Sant Pau, Barcelona, 08025, Spain|Hospital Universitario Vall d′Hebron, Barcelona, 08035, Spain|Hospital Universitario Vall d′Hebron, Barcelona, Spain|Complejo Hospitalario de Castellón, Castelló de la Plana, 12002, Spain|Complejo Hospitalario San Pedro de Alcántara, Cáceres, 10003, Spain|Hospital Universitario Reina Sofia, Córdoba, 14004, Spain|Hospital Marina Salud de Denia, Denia, 03700, Spain|Complejo Hospitalario de Jaén, Jaén, 23007, Spain|Hospital Universitari Arnau de Vilanova de Lleida, Lleida, 25198, Spain|Hospital Universitario Ramon y Cajal, Madrid, 28034, Spain|Hospital Universitario Clínico San Carlos, Madrid, 28040, Spain|Hospital Universitario 12 de Octubre, Madrid, 28041, Spain|Hospital Universitario Puerta de Hierro de Majadahonda, Madrid, 28222, Spain|Hospital Universitario Virgen de la Arrixaca, Murcia, 30120, Spain|Hospital Universitari Sant Joan de Reus, Reus, 43201, Spain|Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, 15706, Spain|Hospital Virgen de la Macarena, Sevilla, 41007, Spain|Hospital Universitario Virgen del Rocío, Sevilla, 41013, Spain|Hospital de Torrevieja, Torrevieja, 03186, Spain|Hospital Clinico Universitario de Valencia, Valencia, 46010, Spain|Hospital Arnau de Vilanova de Valencia, Valencia, 46015, Spain|Hospital Universitario Lozano Blesa, Zaragoza, 50009, Spain Less << |
NCT00069277 | Cancer | PHASE1 | COMPLETED | 2025-04-05 | Cancer Institute Medical Group... More >>, Los Angeles, California, 90025, United States|Premiere Oncology, Santa Monica, California, 90404, United States|New Brunswick, New Jersey, 08901, United States Less << |
NCT00326950 | Cancer | PHASE1 | COMPLETED | 2025-02-08 | Kashiwa, Chiba-prefecture, 277... More >>-0882, Japan Less << |
NCT00278993 | Prostate Cancer | PHASE2 | COMPLETED | 2025-01-08 | Dr. Robert Jotte, Denver, Colo... More >>rado, 80218, United States|Melbourne Internal Medicine Associates, Melbourne, Florida, 32901, United States|Ocala Oncology Center PL, Ocala, Florida, 34474, United States|Central Indiana Cancer Centers, Indianapolis, Indiana, 46227, United States|Minnesota Hematology Oncology, Burnsville, Minnesota, 33557, United States|Missouri Cancer Associates, Columbia, Missouri, 65201, United States|New York Oncology Hematology, P.C., Albany, New York, 12208, United States|St. Luke's Roosevelt Hospital Center, New York, New York, 10019, United States|Columbia University Medical Center, New York, New York, 10032, United States|Raleigh Hematology Oncology Associates PL, Raleigh, North Carolina, 27607, United States|US Oncology, Dallas, Texas, 75204, United States|Mary Crowley Medical Research Center, Dallas, Texas, 75246, United States|El Paso Cancer Treatment Center, El Paso, Texas, 79915, United States|Texas Oncology PA, Fort Worth, Texas, 76104, United States|Texas Oncology PA, Tyler, Texas, 75702, United States|Tyler Cancer Center, Tyler, Texas, 75702, United States|Deke Slayton Cancer Center, Webster, Texas, 77598, United States|Virginia Oncology Associates, Norfolk, Virginia, 23505, United States Less << |
NCT01941407 | Metastatic Breast Cancer | PHASE2 | COMPLETED | 2025-03-16 | Centre Paul Papin, Angers, Fra... More >>nce|Centre Hospitalier d'Auxerre, Auxerre, 89000, France|Institut Ste Catherine, Avignon, France|Clinique Tivoli, Bordeaux, France|H?pital Fleyriat, Bourg-en-Bresse, 01012, France|H?pital Morvan - Centre Hospitalier Universitaire, Brest, 29200, France|centre Francois baclesse, Caen, France|H?pital Privé Sainte-Marie, Chalon sur Sa?ne, 71100, France|Centre Hospitalier William Morey, Chalon sur Sa?ne, France|Centre d'Oncologie et de Radiothérapie, Dijon, 21000, France|Centre Hospitalier la Dracénie, Draguignan, 83300, France|Centre Hospitalier Intercommunal, Fréjus, France|H?pital Privé Dr?me Ardèche - Clinique Pasteur, Guilherand-Granges, 07500, France|Clinique de la Sauvegarde, Lyon, 69337, France|Centre Léon Bérard, Lyon, 69373, France|H?pital Privé Clairval, Marseille, France|H?pital de Mont-de-Marsan, Mont-de-Marsan, 40024, France|Centre d'oncologie de Gentilly, Nancy, France|Centre Catherine de Sienne, Nantes, France|Centre Antoine Lacassagne, Nice, France|Centre Hospitalier Régional, Orléans, France|Institut Curie - Hopital Claudius Régaud, Paris, 75005, France|H?pital Cochin, Paris, 75014, France|Groupe Hospitalier Saint-Joseph, Paris, 75674, France|Centre Catalan d'Oncologie, Perpignan, 66000, France|Centre Hospitalier Lyon-sud, Pierre-Bénite, 69495, France|Centre Hospitalier de la Région d'Annecy, Pringy, 74374, France|Clinique Courlancy, Reims, 51100, France|Institut Jean Godinot, Reims, France|Centre Henri Becquerel, Rouen, France|Clinique Armoricaine de Radiologie, Saint Brieuc, France|Anne-Claire Hardy-Bessard, MD, Saint-Brieuc, 22015, France|Centre Hospitalier Privé de Saint-Grégoire, Saint-Grégoire, 35760, France|GHPSO - Site Senlis, Senlis, 60309, France|Centre de Radiothérapie - Clinique Sainte-Anne, Strasbourg, 67000, France|Centre Hospitalier de Thonon-les-Bains, Thonon-Les-Bains, 74203, France|Clinique Pasteur, Toulouse, 31076, France|CHU Bretonneau, Tours, France|Centre Hospitalier de Valence, Valence, 26953, France|Centre Hospitalier Bretagne Atlantique, Vannes, France Less << |
NCT02551263 | Breast Cancer | COMPLETED | 2025-07-20 | Kobe City Medical Center Gener... More >>al Hospital, Kobe-city, Hyogo-prefecture, 650-0047, Japan|Kyoto University Hospital, Kyoto-city, Kyoto-prefecture, 606-8507, Japan Less << | |
NCT01827787 | Breast Cancer | PHASE2 | COMPLETED | 2025-05-16 | Eastern Maine Medical Center, ... More >>Bangor, Maine, 04402, United States|Dana-Farber Cancer Institute at Faulkner Hospital, Boston, Massachusetts, 02130, United States|Beth Israel Deaconess Medical Center, Boston, Massachusetts, 02215, United States|Dana-Farber Cancer Institute, Boston, Massachusetts, 02215, United States|DF/BWCC at Milford Regional Cancer Center, Milford, Massachusetts, 01757, United States|South Shore Hospital, Weymouth, Massachusetts, 02190, United States|Dana-Farber/New Hampshire Oncology-Hematology, Londonderry, New Hampshire, 03053, United States Less << |
NCT03840772 | Solitary Fibrous Tumor | PHASE2 | COMPLETED | 2024-09-18 | Azienda Ospedaliera Universita... More >>ria Paolo Giaccone, Palermo, PA, 90127, Italy|Policlinico Universitario Campus Biomedico, Roma, RM, 00128, Italy|Fondazione IRCCS INT Milano, Milano, 20133, Italy Less << |
NCT03795012 | Breast Cancer | PHASE2 | TERMINATED | 2021-03-31 | Hospital de Jaén, Jaen, Jaén, ... More >>Spain|Hospital Quiron Dexeus, Barcelona, Please Select, Spain|Institut Català d'Oncologia, Girona, Spain|Complejo Asistencial Universitario de León, León, Spain|Hospital Ramón y Cajal, Madrid, Spain|Hospital Universitario La Paz,, Madrid, Spain|Hospital Son Llatzer, Palma De Mallorca, Spain|Hospital Universitario Dr Peset, Valencia, Spain|Hospital Miguel Servet, Zaragoza, Spain Less << |
NCT00413192 | Soft Tissue Sarcoma | PHASE2 | COMPLETED | 2025-02-13 | Brussels, BE 1000, Belgium|Leu... More >>ven, BE 3000, Belgium|Aarhus, DK 8000, Denmark|Herlev, DK 2730, Denmark|Bordeaux, 33076, France|Lyon, 69008, France|Marseille, 13385, France|Villejuif, 94805, France|Bad Saarow, 15526, Germany|Dresden, DE 01307, Germany|Essen, DE 45122, Germany|Hannover, DE 30625, Germany|Mannheim, DE 68135, Germany|Tuebingen, DE 72076, Germany|Warsaw, 02 781, Poland Less << |
NCT01432886 | Breast Cancer | PHASE1 | COMPLETED | 2025-12-13 | Kashiwa-shi, Chiba, Japan|Hida... More >>ka-shi, Saitama, Japan Less << |
NCT02681523 | Breast Cancer | PHASE2 | TERMINATED | 2018-07-24 | Charing Cross Hopsital, London... More >>, W6 8RF, United Kingdom Less << |
NCT03637868 | Metastatic Breast Cancer | PHASE2 | WITHDRAWN | 2020-04-14 | Institut de Cancerologie de L'... More >>Ouest - Paul Papin, Angers, France|Institut Sainte Catherine, Avignon, France|CHU Besan?on, Besan?on, France|Institut Paoli-Calmettes, Marseille, 13009, France|Institut Du Cancer de Montpellier, Montpellier, 34298, France|Institut De Cancérologie de l'Ouest, Saint-Herblain, France|Institut de Cancerologie de Lorraine Alexis Vautrin, Vand?uvre-lès-Nancy, France Less << |
NCT00069264 | Advanced Solid Tumors | PHASE1 | COMPLETED | 2025-07-05 | Bronx, New York, 10461, United... More >> States|San Antonio, Texas, United States Less << |
NCT00246090 | Breast Cancer | PHASE2 | COMPLETED | 2025-09-07 | Birmingham Hematology and Onco... More >>logy, Birmingham, Alabama, 35205, United States|Birmingham Hematology and Oncology, Birmingham, Alabama, 35213, United States|Mercy Cancer Center, Hot Springs, Arkansas, 71913, United States|Arkansas Cancer Research Center, Little Rock, Arkansas, 72205, United States|Wilshire Oncology Medical Group, Inc., La Verne, California, 91750, United States|Rocky Mountain Cancer Center-Midtown, Denver, Colorado, 80218, United States|Rocky Mountain Cancer Center-Rose, Denver, Colorado, 80220, United States|Rocky Mountain Cancer Center, Littleton, Colorado, 80210, United States|Cancer Research Network, Plantation, Florida, 33324, United States|Hematology-Oncology Associates, Port Saint-Lucie, Florida, 34952, United States|Dr. Elizabeth Tan-Chiu, PA, Tamarac, Florida, 33321, United States|Peachtree Hematology And Oncology Consultants, Atlanta, Georgia, 30309, United States|University of Chicago, Chicago, Illinois, 60637, United States|Decatur Memorial Hospital, Decatur, Illinois, 62526, United States|Cancer Care and Hematology Specialist of Chicagoland, Niles, Illinois, 60714, United States|Central Indiana Cancer Center, Indianapolis, Indiana, 46227, United States|Monroe Medical Center, Munster, Indiana, 46321, United States|Northern Indiana Cancer Research Consortium, South Bend, Indiana, 46601, United States|University of Kansas Medical Center, Kansas City, Kansas, 66160, United States|Frederick Memorial Hospital, Regional Cancer Therapy Center, Frederick, Maryland, 21701, United States|Park Nicollet Institute, Minneapolis, Minnesota, 55416, United States|Missouri Cancer Associates, Columbia, Missouri, 65201, United States|Montana Cancer Specialists, Missoula, Montana, 59802, United States|Comprehensive Cancer Centers of Nevada, Henderson, Nevada, 89052, United States|New York Oncology Hematology, P.C, Albany, New York, 12208, United States|North Shore Hematology Oncology Associates, East Setakuet, New York, 11733, United States|Huntington Medical Group, PC, Huntington Station, New York, 11746, United States|Weill Cornell Breast Cancer Center, New York, New York, 10021, United States|SUNY Upstate Medical University, Syracuse, New York, 13210, United States|Northwestern Carolina Oncology And Hematology, PA, Hudson, North Carolina, 28602, United States|Raleigh Hematology Oncology Associates, Raleigh, North Carolina, 27511, United States|'Signal Point Hematology/Oncology, Inc., Middletown, Ohio, 45042, United States|Medical University of Ohio, Toledo, Ohio, 43614, United States|Cancer Care Associates, Oklahoma City, Oklahoma, 73112, United States|Cancer Care Associates, Oklahoma City, Oklahoma, 73120, United States|Cancer Care Associates, Tulsa, Oklahoma, 74136, United States|Willamette Valley Cancer Center, Eugene, Oregon, 97401, United States|Northwest Cancer Specialist Rose Qtr, Portland, Oregon, 97225, United States|Kaiser Permanente, Central Interstate Clinic, Hematology Oncology, Portland, Oregon, 97227, United States|Northwest Cancer Specialist Hoyt, Portland, Oregon, 97227, United States|Charleston Hematology Oncology, Charleston, South Carolina, 29403, United States|University of Tennessee Medical Center, Knoxville, Tennessee, 37920, United States|Harrington Cancer Center, Amarillo, Texas, 79106, United States|Texas Oncology, P.A. Bedford, Bedford, Texas, 76022, United States|Center For Oncology Research and Treatment, PA, Dallas, Texas, 75230, United States|Texas Oncology PA, Dallas, Texas, 75231, United States|Sammons Cancer Center-Dallas, Dallas, Texas, 75246, United States|El Paso Cancer Treatment Center West, El Paso, Texas, 79902, United States|El Paso Cancer Treatment Center, El Paso, Texas, 79915, United States|Texas Oncology PA, Houston, Texas, 77024, United States|Baylor College of Medicine, Breast Cancer Clinic, Houston, Texas, 77030, United States|North Texas Regional Cancer Center, Plano, Texas, 75075, United States|Tyler Cancer Center, Tyler, Texas, 75702, United States|Valley Oncology PA, Weslaco, Texas, 78596, United States|Utah Cancer Specialists, Salt Lake City, Utah, 84106, United States|Fairfax Northern VA Hematology Oncology PC, Fairfax, Virginia, 22031, United States|Oncology and Hematology Associates, Salem, Virginia, 24153, United States|Cancer Care Northwest, Spokane, Washington, 99218, United States|Northwest Cancer Specialist, Vancouver, Washington, 98684, United States|Yakima Valley Memorial Hospital, Yakima, Washington, 98902, United States|Hamilton Health Sciences Juravinski Cancer Centre, Hamilton, Ontario, L8VSC2, Canada|NW Ontario Regional Cancer Centre, Thunder Bay, Ontario, P7B6V4, Canada|Toronto East General Hospital, Toronto, Ontario, M4C3E7, Canada|Centre Hospitaliere Universitaire de Montreal, Montreal, Quebec, H2L4MI, Canada|McGill University, Dept. of Oncology, Clinical Research Program, Montreal, Quebec, H2W1S6, Canada Less << |
NCT03027245 | Locally Advanced or Metastatic... More >> Breast Cancer Less << | COMPLETED | 2022-05-31 | Eisai Trial Site 1, Amberg, Ge... More >>rmany|Eisai Trial Site 1, Aschaffenburg, Germany|Eisai Trial Site 2, Aschaffenburg, Germany|Eisai Trial Site 1, Augsburg, Germany|Eisai Trial Site 2, Augsburg, Germany|Eisai Trial Site 1, Aurich, Germany|Eisai Trial Site 1, Berlin, Germany|Eisai Trial Site 2, Berlin, Germany|Eisai Trial Site 3, Berlin, Germany|Eisai Trial Site 1, Bonn, Germany|Eisai Trial Site 2, Bonn, Germany|Eisai Trial Site 1, Darmstadt, Germany|Eisai Trial Site 1, Donauworth, Germany|EISAI Trial Site 1, Dresden, Germany|Eisai Trial Site 1, Duren, Germany|Eisai Trial Site 1, Essen, Germany|Eisai Trial Site 1, Esslingen, Germany|Eisai Trial Site 1, Eutin, Germany|Eisai Trial Site 1, Freiburg, Germany|Eisai Trial Site 1, Furstenwalde, Germany|Eisai Trial Site 1, Gelsenkirchen, Germany|Eisai Trial Site 1, Georgsmarienhütte, Germany|Eisai Trial Site 1, Greifswald, Germany|Eisai Trial Site 1, Hannover, Germany|Eisai Trial Site 2, Hannover, Germany|Eisai Trial Site 1, Hof, Germany|Eisai Trial Site 1, Homburg, Germany|Eisai Trial Site 1, Ilsede, Germany|Eisai Trial Site 1, Karlsruhe, Germany|Eisai Trial Site 1, Kassel, Germany|Eisai Trial Site 1, Kiel, Germany|Eisai Trial Site 2, Kiel, Germany|Eisai Trial Site 1, Koblenz, Germany|Eisai Trial Site 1, Koln, Germany|Eisai Trial Site 2, Koln, Germany|Eisai Trial Site 1, Lahr, Germany|Eisai Trial Site 1, Landshut, Germany|Eisai Trial Site 1, Lemgo, Germany|Eisai Trial Site 1, Lubeck, Germany|Eisai Trial Site 1, Magdeburg, Germany|Eisai Trial Site 1, Mainz, Germany|Eisai Trial Site 1, Mannheim, Germany|Eisai Trial Site 1, Marktredwitz, Germany|Eisai Trial Site 1, Munchen, Germany|Eisai Trial Site 2, Munchen, Germany|Eisai Trial Site 3, Munchen, Germany|Eisai Trial Site 1, Munster, Germany|Eisai Trial Site 1, Münster, Germany|Eisai Trial Site 1, Naunhof, Germany|Eisai Trial Site 1, Nurnberg, Germany|Eisai Trial Site 1, Oberhausen, Germany|Eisai Trial Site 1, Offenbach, Germany|Eisai Trial Site 1, Offenburg, Germany|Eisai Trial Site 1, Oldenburg, Germany|Eisai Trial Site 1, Potsdam, Germany|Eisai Trial Site 1, Puttlingen, Germany|Eisai Trial Site 1, Quedlinburg, Germany|Eisai Trial Site 1, Rodgau, Germany|Eisai Trial Site 1, Rotenburg, Germany|Eisai Trial Site 1, Saarlouis, Germany|Eisai Trial Site 1, Stolberg, Germany|Eisai Trial Site 1, Stuttgart, Germany|Eisai Trial Site 2, Stuttgart, Germany|Eisai Trial Site 1, Tubingen, Germany|Eisai Trial Site 1, Villingen-Schwenningen, Germany|Eisai Trial Site 1, Worms, Germany Less << | |
NCT03331250 | Angiosarcoma|Epithelioid Heman... More >>gioendothelioma Less << | PHASE2 | ACTIVE_NOT_RECRUITING | 2025-05-31 | Massachusetts General Hospital... More >>, Boston, Massachusetts, 02114, United States|Dana Farber Cancer Institute, Boston, Massachusetts, 02115, United States Less << |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
1.37mL 0.27mL 0.14mL |
6.85mL 1.37mL 0.69mL |
13.70mL 2.74mL 1.37mL |
Tags: Eribulin | ER-086526 | Microtubule/Tubulin | ADC Toxins | Cell Cycle | Cytoskeleton | Antibody-Drug Conjugate/ADC Related | 253128-41-5
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
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