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Chemical Structure| 2765082-12-8 Chemical Structure| 2765082-12-8

Structure of RMC-7977
CAS No.: 2765082-12-8

Chemical Structure| 2765082-12-8

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RMC-7977 is a broad-spectrum tri-complex RAS inhibitor capable of inhibiting both mutant and wild-type KRAS, NRAS, and HRAS, especially showing significant antitumor activity in RAS-dependent tumors, suitable for RAS-driven cancer research. This compound demonstrates good tolerability and anticancer effects in various preclinical cancer models.

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Product Details of RMC-7977

CAS No. :2765082-12-8
Formula : C47H60N8O6S
M.W : 865.09
SMILES Code : O=C1OCC(C)(C)CC=2C3=CC(=CC=C3N(C2C=4C=C(C=NC4C(OC)C)N5CCN(CC5)C6CC6)CC)C=7N=C(SC7)CC(NC(=O)C8C9COCC89)C(=O)N%10NC1CCC%10
MDL No. :N/A

Safety of RMC-7977

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of RMC-7977

GPCR

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.16mL

0.23mL

0.12mL

5.78mL

1.16mL

0.58mL

11.56mL

2.31mL

1.16mL

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