Alternatived Products of [ 2860-55-1 ]
Product Details of [ 2860-55-1 ]
CAS No. : | 2860-55-1 |
MDL No. : | MFCD20639298 |
Formula : |
C8H7NO5
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
197.15
|
Pubchem ID : | - |
Synonyms : |
|
Safety of [ 2860-55-1 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 2860-55-1 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 2860-55-1 ]
- 1
-
[ 90110-69-3 ]
-
[ 2860-55-1 ]
Yield | Reaction Conditions | Operation in experiment |
|
With hydrogenchloride; sodium nitrite |
|
- 2
-
[ 2860-55-1 ]
-
[ 41516-33-0 ]
Yield | Reaction Conditions | Operation in experiment |
|
With hydrogenchloride |
|
- 3
-
[ 67-56-1 ]
-
[ 2860-55-1 ]
-
[ 82140-59-8 ]
-
[ 82140-73-6 ]
Yield | Reaction Conditions | Operation in experiment |
|
With phosphorus pentachloride; trichlorophosphate 1.) reflux, 2 h, 2.) reflux, 2 h; Yield given. Multistep reaction. Yields of byproduct given; |
|
- 4
-
[ 2860-55-1 ]
-
2-Chloro-6-methyl-pyridine-3,4-dicarbonyl dichloride
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
With phosphorus pentachloride; trichlorophosphate for 2h; Heating; |
|
Yield | Reaction Conditions | Operation in experiment |
|
Rk. m. Formamid (Δ auf Siedetemp.) zu 2-Hydroxy-6-methyl-pyridin-3,4-dicarbonsaeure-imid (S. 1405); |
|
|
Rk. m. ws. HCl (mehrstuendiges Δ auf Siedetemp.) zu 2-Hydroxy-6-methyl-isonicotinsaeure; |
|
Yield | Reaction Conditions | Operation in experiment |
|
4-Ethoxycarbonyl-3-cyan-2-hydroxy-6-methyl-pyridin, wss. NaOH, Δ; |
|
|
2-Hydroxy-6-methyl-pyridin-3,4-dicarbonsaeure-imid, wss. NaOH (3h Siedetemp.); |
|
|
3-Hydroxy-6-methyl-1-pyrazolo<3,4-b>pyridin-4-carbonsaeure-ethylester, Eg. wss. NaNO2; |
|
|
3-Hydroxy-6-methyl-1-pyrazolo<3,4-b>pyridin-4-carbonsaeure-hydrazid, Eg. wss. NaNO2; |
|
|
2-Amino-6-methyl-pyridin-3,4-dicarbonsaeure, Eg., NaNO2; |
|
|
3-Cyan-2-hydroxy-6-methyl-pyridin-4-carbonsaeure, wss. NaOH (3h Siedetemp.); |
|
- 7
-
[ 2860-55-1 ]
-
[ 82140-59-8 ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 3 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature |
|
- 8
-
[ 2860-55-1 ]
-
[ 82140-60-1 ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 3 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: hydrogen chloride / methanol / 3.5 h / Heating
3: aq. ammonia |
|
|
Multi-step reaction with 5 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: hydrogen chloride / methanol / 3.5 h / Heating
5: aq. ammonia |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 9
-
[ 2860-55-1 ]
-
[ 82140-61-2 ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 3 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: hydrogen chloride / methanol / 3.5 h / Heating
3: aq. ammonia |
|
|
Multi-step reaction with 5 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: hydrogen chloride / methanol / 3.5 h / Heating
5: aq. ammonia |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 10
-
[ 2860-55-1 ]
-
[ 82140-62-3 ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 3 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: hydrogen chloride / methanol / 3.5 h / Heating
3: aq. ammonia |
|
|
Multi-step reaction with 5 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: hydrogen chloride / methanol / 3.5 h / Heating
5: aq. ammonia |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 11
-
[ 2860-55-1 ]
-
2-Chloro-3-chlorocarbonyl-6-methyl-isonicotinic acid methyl ester
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h |
|
- 12
-
[ 2860-55-1 ]
-
3,7-Dimethyl-2-[(E)-methylimino]-4-oxo-3,4-dihydro-2H-pyrido[3,2-e][1,3]thiazine-5-carboxylic acid methyl ester
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 3 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: hydrogen chloride / methanol / 3.5 h / Heating
3: aq. ammonia |
|
|
Multi-step reaction with 5 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: hydrogen chloride / methanol / 3.5 h / Heating
5: aq. ammonia |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 13
-
[ 2860-55-1 ]
-
3-Ethyl-2-[(E)-ethylimino]-7-methyl-4-oxo-3,4-dihydro-2H-pyrido[3,2-e][1,3]thiazine-5-carboxylic acid methyl ester
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 3 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: hydrogen chloride / methanol / 3.5 h / Heating
3: aq. ammonia |
|
|
Multi-step reaction with 5 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: hydrogen chloride / methanol / 3.5 h / Heating
5: aq. ammonia |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 14
-
[ 2860-55-1 ]
-
2-[(E)-Allylimino]-3,7-dimethyl-4-oxo-3,4-dihydro-2H-pyrido[3,2-e][1,3]thiazine-5-carboxylic acid methyl ester
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 3 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: hydrogen chloride / methanol / 3.5 h / Heating
3: aq. ammonia |
|
|
Multi-step reaction with 5 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: hydrogen chloride / methanol / 3.5 h / Heating
5: aq. ammonia |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 15
-
[ 2860-55-1 ]
-
2-[(E)-Butylimino]-3,7-dimethyl-4-oxo-3,4-dihydro-2H-pyrido[3,2-e][1,3]thiazine-5-carboxylic acid methyl ester
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 3 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: hydrogen chloride / methanol / 3.5 h / Heating
3: aq. ammonia |
|
|
Multi-step reaction with 5 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: hydrogen chloride / methanol / 3.5 h / Heating
5: aq. ammonia |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 16
-
[ 2860-55-1 ]
-
[ 82140-67-8 ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: 20 percent / hydrogen chloride / methanol / 10 h / Heating |
|
|
Multi-step reaction with 4 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: 20 percent / hydrogen chloride / methanol / 10 h / Heating |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 17
-
[ 2860-55-1 ]
-
1,7-Dimethyl-4-oxo-3-phenyl-2-thioxo-1,2,3,4-tetrahydro-pyrido[2,3-d]pyrimidine-5-carboxylic acid methyl ester
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: 15 percent / hydrogen chloride / methanol / 10 h / Heating |
|
|
Multi-step reaction with 4 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: 15 percent / hydrogen chloride / methanol / 10 h / Heating |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 18
-
[ 2860-55-1 ]
-
3,7-Dimethyl-4-oxo-1-phenyl-2-thioxo-1,2,3,4-tetrahydro-pyrido[2,3-d]pyrimidine-5-carboxylic acid methyl ester
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: 10 percent / hydrogen chloride / methanol / 10 h / Heating |
|
|
Multi-step reaction with 4 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: 10 percent / hydrogen chloride / methanol / 10 h / Heating |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 19
-
[ 2860-55-1 ]
-
1-Butyl-7-methyl-4-oxo-3-phenyl-2-thioxo-1,2,3,4-tetrahydro-pyrido[2,3-d]pyrimidine-5-carboxylic acid
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 3 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: 20 percent / hydrogen chloride / methanol / 10 h / Heating
3: 85 percent / conc. hydrochloric acid / acetic acid / 6 h / Heating |
|
|
Multi-step reaction with 5 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: 20 percent / hydrogen chloride / methanol / 10 h / Heating
5: 85 percent / conc. hydrochloric acid / acetic acid / 6 h / Heating |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 20
-
[ 2860-55-1 ]
-
[ 82140-68-9 ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: 20 percent / hydrogen chloride / methanol / 10 h / Heating |
|
|
Multi-step reaction with 4 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: 20 percent / hydrogen chloride / methanol / 10 h / Heating |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 21
-
[ 2860-55-1 ]
-
2-Carbamimidoylsulfanyl-6-methyl-pyridine-3,4-dicarboxylic acid dimethyl ester; hydrochloride
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: hydrogen chloride / methanol / 3.5 h / Heating |
|
|
Multi-step reaction with 4 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: hydrogen chloride / methanol / 3.5 h / Heating |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 22
-
[ 2860-55-1 ]
-
6-Methyl-2-methylcarbamimidoylsulfanyl-pyridine-3,4-dicarboxylic acid dimethyl ester; hydrochloride
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: hydrogen chloride / methanol / 3.5 h / Heating |
|
|
Multi-step reaction with 4 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: hydrogen chloride / methanol / 3.5 h / Heating |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 23
-
[ 2860-55-1 ]
-
2-(N,N'-Dimethyl-carbamimidoylsulfanyl)-6-methyl-pyridine-3,4-dicarboxylic acid dimethyl ester; hydrochloride
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: hydrogen chloride / methanol / 3.5 h / Heating |
|
|
Multi-step reaction with 4 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: hydrogen chloride / methanol / 3.5 h / Heating |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 24
-
[ 2860-55-1 ]
-
2-Allylcarbamimidoylsulfanyl-6-methyl-pyridine-3,4-dicarboxylic acid dimethyl ester; hydrochloride
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: hydrogen chloride / methanol / 3.5 h / Heating |
|
|
Multi-step reaction with 4 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: hydrogen chloride / methanol / 3.5 h / Heating |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 25
-
[ 2860-55-1 ]
-
2-(N,N'-Diethyl-carbamimidoylsulfanyl)-6-methyl-pyridine-3,4-dicarboxylic acid dimethyl ester; hydrochloride
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: hydrogen chloride / methanol / 3.5 h / Heating |
|
|
Multi-step reaction with 4 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: hydrogen chloride / methanol / 3.5 h / Heating |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 26
-
[ 2860-55-1 ]
-
2-(N-Allyl-N'-methyl-carbamimidoylsulfanyl)-6-methyl-pyridine-3,4-dicarboxylic acid dimethyl ester; hydrochloride
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: hydrogen chloride / methanol / 3.5 h / Heating |
|
|
Multi-step reaction with 4 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: hydrogen chloride / methanol / 3.5 h / Heating |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 27
-
[ 2860-55-1 ]
-
2-(N-Butyl-N'-methyl-carbamimidoylsulfanyl)-6-methyl-pyridine-3,4-dicarboxylic acid dimethyl ester; hydrochloride
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 2 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: hydrogen chloride / methanol / 3.5 h / Heating |
|
|
Multi-step reaction with 4 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: hydrogen chloride / methanol / 3.5 h / Heating |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
- 28
-
[ 2860-55-1 ]
-
[ 82140-71-4 ]
Yield | Reaction Conditions | Operation in experiment |
|
Multi-step reaction with 3 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: 20 percent / hydrogen chloride / methanol / 10 h / Heating
3: 85 percent / conc. hydrochloric acid / acetic acid / 6 h / Heating |
|
|
Multi-step reaction with 5 steps
1: 1.) POCl3, PCl5 / 1.) reflux, 2 h, 2.) reflux, 2 h
2: thionyl chloride / 1.) room temperature, 1 h, 2.) reflux 2 h
3: benzene / 1 h / Ambient temperature
4: 20 percent / hydrogen chloride / methanol / 10 h / Heating
5: 85 percent / conc. hydrochloric acid / acetic acid / 6 h / Heating |
|
Reference:
[1]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]
[2]Zawisza; Siwinska; Sladowska; Jakobiec
[Farmaco, Edizione Scientifica, 1982, vol. 37, # 4, p. 266 - 274]