Home Cart Sign in  
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 29110-48-3 Chemical Structure| 29110-48-3

Structure of Guanfacine HCl
CAS No.: 29110-48-3

Chemical Structure| 29110-48-3

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

Guanfacine HCl is a centrally acting antihypertensive with α2-adrenoceptor agonist with Kd value of 31 nM for α2A-adrenoceptor while displaying 60-fold selectivity over α2B-adrenoceptors, causing a decrease in heart rate and peripheral vascular resistance.

Synonyms: Guanfacine (hydrochloride); Guanfacine Hydrochloride; Intuniv

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of Guanfacine HCl

CAS No. :29110-48-3
Formula : C9H10Cl3N3O
M.W : 282.55
SMILES Code : O=C(NC(N)=N)CC1=C(Cl)C=CC=C1Cl.[H]Cl
Synonyms :
Guanfacine (hydrochloride); Guanfacine Hydrochloride; Intuniv
MDL No. :MFCD00798230

Safety of Guanfacine HCl

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301
Precautionary Statements:P264-P270-P301+P310+P330-P405-P501
Class:6.1
UN#:2811
Packing Group:

Related Pathways of Guanfacine HCl

GPCR

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT02204410 Attention Deficit Hyperactivit... More >>y Disorder Deficient Emotional Self-Regulation Less << Phase 4 Completed - United States, Massachusetts ... More >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Less <<
NCT01172288 Tourettes Syndrome ... More >> Tic Less << Phase 2 Completed - United States, Connecticut ... More >> Yale Child Study Center New Haven, Connecticut, United States, 06520 Less <<
NCT00684489 Hypertension Not Applicable Completed - -
NCT03337646 Attention Deficit Hyperactivit... More >>y Disorder Autism Spectrum Disorder Less << Phase 4 Recruiting October 2019 Canada, Ontario ... More >> Center for Pediatric Excellence Recruiting Ottawa, Ontario, Canada, K2G1W2 Contact: Judy van Stralen, MD    6137267355    judy@cfpe.ca    Contact: Amanda Smart    6137267355    amanda@cfpe.ca    Principal Investigator: Judy van Stralen, MD Less <<
NCT00142948 Heroin Dependence Phase 2 Completed - Russian Federation ... More >> Saint Petersburg Pavlov State Medical University Saint Petersburg, Russian Federation Less <<
NCT01172288 - Completed - -
NCT00109642 - Completed - United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less <<
NCT02204410 - Completed - -
NCT01133847 Attention Deficit Hyperactivit... More >>y Disorder Reading Disabilities Less << Phase 4 Completed - United States, Ohio ... More >> Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, United States, 45206 United States, Texas University of Texas Health Science Center Houston, Texas, United States, 77030 Less <<
NCT00223717 Hypertension Phase 1 Completed - United States, Tennessee ... More >> Vanderbilt University Nashville, Tennessee, United States, 37232 Less <<
NCT02136147 - Enrolling by invitation - Sweden ... More >> Division for Child and Adolescent Psychiatry in Stockholm Stockholm, Stockholm county, Sweden Less <<
NCT02788851 Attention Deficit Hyperactivit... More >>y Disorder (ADHD) Less << Not Applicable Active, not recruiting December 2018 Canada, Quebec ... More >> Montreal Children's Hospital Montreal, Quebec, Canada, H4A 3J1 Less <<
NCT01133847 - Completed - -
NCT00025779 Attention Deficit Disorder Wit... More >>h Hyperactivity Autistic Disorder Pervasive Development Disorders Less << Not Applicable Completed - United States, California ... More >> UCLA Neuropsychiatric Institute Los Angeles, California, United States, 90024 United States, Connecticut Yale Child Study Center New Haven, Connecticut, United States, 06520 United States, Indiana Indiana University-Riley Hospital for Children Indianapolis, Indiana, United States, 46202 United States, Maryland Kennedy Krieger Institute Baltimore, Maryland, United States, 21231 United States, Ohio Ohio State University Columbus, Ohio, United States, 43210 Less <<
NCT00919867 Healthy Phase 1 Completed - United States, New Jersey ... More >> Advanced Biomedical Research, Inc. Hackensack, New Jersey, United States Less <<
NCT00150592 - Completed - -
NCT00150592 Attention Deficit Disorder Wit... More >>h Hyperactivity Less << Phase 2 Completed - -
NCT00919867 - Completed - -
NCT00150618 Attention Deficit Disorder Wit... More >>h Hyperactivity Less << Phase 3 Completed - -
NCT00152009 Attention Deficit Disorder Wit... More >>h Hyperactivity Less << Phase 3 Completed - -
NCT00152009 - Completed - -
NCT00151996 - Completed - -
NCT00150618 - Completed - -
NCT00613015 Cocaine Related Disorders Phase 2 Completed - United States, South Carolina ... More >> Medical University of South Carolina-GCRC Charleston, South Carolina, United States, 29425 Less <<
NCT00734578 ADHD Phase 3 Completed - -
NCT00151996 Attention Deficit Disorder Wit... More >>h Hyperactivity Less << Phase 2 Completed - -
NCT00734578 - Completed - -
NCT01470469 - Completed - -
NCT01470469 Generalized Anxiety Disorder (... More >>GAD) Anxiety, Separation Phobia, Social Less << Phase 2 Completed - -
NCT00901576 Healthy Phase 1 Completed - United States, New Jersey ... More >> Advanced Biomedical Research, Inc. Hackensack, New Jersey, United States, 07601 Less <<
NCT00613015 - Completed - -
NCT00389779 Hypertension Phase 3 Completed - -
NCT00901576 - Completed - -
NCT00389675 Hypertension Phase 3 Terminated(Study DAR-312 did n... More >>ot meet its primary co-endpoints.) Less << - -
NCT00004376 Tourette Syndrome Phase 3 Completed - -
NCT01985581 Attention Deficit Hyperactivit... More >>y Disorder Less << Phase 4 Completed - Canada, Ontario ... More >> JPM van Stralen Medicine Professional Corporation Ottawa, Ontario, Canada, K2G1W2 Less <<
NCT00773357 Smoking Phase 2 Active, not recruiting July 2019 United States, Connecticut ... More >> Yale Center for Clinical Investigation, Yale University New Haven, Connecticut, United States, 06519 Less <<
NCT02259517 Attention Deficit Hyperactivit... More >>y Disorder Less << Not Applicable Recruiting July 2020 United States, New York ... More >> New York State Psychiatric Institute Recruiting New York, New York, United States, 10032 Contact: Jonathan Posner, MD    646-774-5735    PosnerJ@nyspi.columbia.edu    Principal Investigator: Jonathan Posner, MD Less <<
NCT01985581 - Completed - -
NCT00353379 Schizotypal Personality Disord... More >>er Personality Disorders Less << Phase 4 Terminated(low enrollment) - United States, New York ... More >> Icahn School of Medicine at Mount Sinai New York, New York, United States, 10029 Less <<
NCT00429273 Attention Deficit Disorder Wit... More >>h Hyperactivity Less << Phase 4 Completed - United States, California ... More >> University of California Los Angeles Los Angeles, California, United States, 90095 Less <<
NCT00429273 - Completed - -
NCT00358969 Borderline Personality Disorde... More >>r Less << Not Applicable Unknown - United States, New York ... More >> Mount Sinai Hospital - Mood & Personality Research Group Recruiting New York, New York, United States, 10029 Less <<
NCT00585754 Cocaine Dependent ... More >> Alcohol Dependent Less << Phase 1 Completed - United States, Connecticut ... More >> Yale University School of Medicine: Yale Stress Center New Haven, Connecticut, United States, 06519 Less <<
NCT01681264 Chronic Pain Phase 4 Recruiting March 2019 United States, Massachusetts ... More >> Center for Translational Pain Research Recruiting Boston, Massachusetts, United States, 02114 Contact: Sarah Roth, B.S    617-724-6102    sroth3@mgh.harvard.edu    Principal Investigator: Jianren Mao, M.D., Ph.D. Less <<
NCT03116126 Alzheimer Disease Phase 3 Not yet recruiting September 2019 United Kingdom ... More >> Imperial Memory Unit, Charing Cross Hospital Recruiting London, United Kingdom, W6 8RF Contact: Team    020 3311 5228    MEMORY.RESEARCH@IMPERIAL.NHS.UK Less <<
NCT00018603 Post-Traumatic Stress Disorder Phase 1 Completed - United States, Connecticut ... More >> VA Connecticut Healthcare System West Haven, Connecticut, United States, 06516 Less <<
NCT02524899 Schizotypal Personality Disord... More >>er SPD Less << Phase 2 Completed - United States, New York ... More >> Icahn School of Medicine at Mount Sinai New York, New York, United States, 10029 Less <<
NCT01081145 Attention-deficit/Hyperactivit... More >>y Disorder Less << Phase 3 Completed - -
NCT00935493 Cognitive Aging Not Applicable Completed - United States, Connecticut ... More >> Alzheimer's Disease Research Unit, Yale University School of Medicine New Haven, Connecticut, United States, 06510 Less <<
NCT01081145 - Completed - -
NCT02699125 Obstructive Sleep Apnea Phase 4 Unknown August 2016 -
NCT01177306 Attention Deficit Hyperactivit... More >>y Disorder Less << Phase 4 Completed - United States, North Carolina ... More >> 3C Family Services Cary, North Carolina, United States, 27513 Less <<
NCT00469664 Schizophrenia ... More >> Schizoaffective Disorder Cognitive Impairment Less << Phase 4 Unknown December 2008 United States, New York ... More >> Bronx VA Medical Center Bronx, New York, United States, 10468 Mount Sinai Medical Center NY, New York, United States, 10029 Pilgrim Psychiatric Center W. Brentwood, New York, United States, 11717 Less <<
NCT01146002 Attention-deficit/Hyperactivit... More >>y Disorder Less << Phase 4 Completed - United States, New Jersey ... More >> Neurology Group of Bergen County Ridgewood, New Jersey, United States, 07450 Less <<
NCT01244490 - Completed - -
NCT03333668 ADHD Not Applicable Not yet recruiting December 31, 2020 United Kingdom ... More >> Institute of Psychiatry, Psychology & Neuroscience; King's College London Not yet recruiting London, United Kingdom, SE5 8AF Contact: Olivia S Kowalczyk, BSc    02078480384    oliwia.s.kowalczyk@kcl.ac.uk    Principal Investigator: Olivia S Kowalczyk, BSc          Sub-Investigator: Katya Rubia, PhD          Sub-Investigator: Mitul A Mehta, PhD Less <<
NCT00935493 - Completed - -
NCT01600885 NMDA Receptor Function Not Applicable Completed - United States, Connecticut ... More >> Connecticut Mental Health Center New Haven, Connecticut, United States, 06511 Yale Magnetic Resonance Research Center New Haven, Connecticut, United States, 06520 Veterans Affairs Hospital West Haven, Connecticut, United States, 06516 Less <<
NCT01600885 - Completed - -
NCT01238575 Pervasive Development Disorder... More >>s Less << Phase 4 Completed - United States, California ... More >> University of California, Los Angeles Los Angeles, California, United States, 90024 United States, Connecticut Yale University New Haven, Connecticut, United States, 06519 United States, Georgia Emory University Atlanta, Georgia, United States, 30329 United States, Massachusetts Massachusetts General Hospital Lexington, Massachusetts, United States, 02142 United States, Washington Seattle Children's Hospital Seattle, Washington, United States, 98101 Less <<
NCT01238575 - Completed - -
NCT00955253 Stroke Hemisp... More >>atial Neglect Less << Phase 2 Completed - United Kingdom ... More >> Imperial College Healthcare NHS Trust London, United Kingdom, W6 8RF Less <<
NCT00367835 - Completed - -
NCT00997984 - Completed - -
NCT01244490 Attention Deficit Hyperactivit... More >>y Disorder Less << Phase 3 Completed - -
NCT01547000 - Completed - -
NCT00997984 Attention-Deficit/Hyperactivit... More >>y Disorder Less << Phase 3 Completed - -
NCT01547000 Tourette Disorder ... More >> Tourette Syndrome Less << Phase 4 Completed - United States, Connecticut ... More >> Yale Child Study Center New Haven, Connecticut, United States, 06510 United States, Florida University of South Florida Tampa, Florida, United States, 33612 United States, New York Mount Sinai School of Medicine New York, New York, United States, 10029 Less <<
NCT01156051 - Terminated(extended beyond com... More >>pletion date; chose to close out rather than renew IRB review) Less << - -
NCT02882854 Postoperative Nausea and Vomit... More >>ing Pain, Postoperative Less << Not Applicable Unknown July 2017 United States, Tennessee ... More >> Vanderbilt University Medical Center Recruiting Nashville, Tennessee, United States, 37212 Principal Investigator: Stephen Harvey, MD Less <<
NCT00367835 ADHD Phase 3 Completed - -
NCT00672984 - Completed - -
NCT02048241 - Completed - -
NCT01069523 Attention Deficit Disorder Wit... More >>h Hyperactivity Less << Phase 4 Completed - United States, Texas ... More >> Dept. Of Psychiatry, University of Texas Health Science Center at San Antonio San Antonio, Texas, United States, 78229-3900 Less <<
NCT01156051 Attention-Deficit/Hyperactivit... More >>y Disorder Attention Deficit Disorder Insomnia Sleep Disorders Less << Phase 4 Terminated(extended beyond com... More >>pletion date; chose to close out rather than renew IRB review) Less << - United States, New Jersey ... More >> Children's Specialized Hospital Hamilton, New Jersey, United States, 08619 Children's Specialized Hospital Toms River, New Jersey, United States, 08755 Less <<
NCT01069523 - Completed - -
NCT02048241 Intermittent Explosive Disorde... More >>r Childhood Aggression Oppositional Defiant Disorder Attention Deficit Disorder Less << Phase 4 Completed - United States, New York ... More >> New York State Psychiatric Institute New York, New York, United States, 10032 Less <<
NCT01500694 Attention Deficit Hyperactivit... More >>y Disorder (ADHD) Less << Phase 3 Completed - -
NCT01500694 - Completed - -
NCT00672984 Healthy Volunteers Phase 1 Completed - United States, Washington ... More >> Charles River Clinical Services Northwest, Inc. Tacoma, Washington, United States Less <<
NCT01081132 Attention-Deficit/Hyperactivit... More >>y Disorder Less << Phase 3 Completed - -
NCT02164422 Alcohol Drinking Phase 2 Recruiting January 2020 United States, Connecticut ... More >> Yale Center for Clinical Investigations, Yale University Recruiting New Haven, Connecticut, United States, 06519 Contact: Paula Cunningham    203-737-3554       Principal Investigator: Sherry A McKee, PhD Less <<
NCT02192398 Chronic Pain Not Applicable Recruiting December 2019 United States, Massachusetts ... More >> MGH Center for Translational Pain Research Recruiting Boston, Massachusetts, United States, 02114 Contact: MGH Center for Translational Pain Research    617-724-6102    mghpainresearch@partners.org    Principal Investigator: Jianren Mao, M.D., Ph.D. Less <<
NCT01709695 - Completed - -
NCT03258476 Stress Disorder Phase 4 Not yet recruiting May 2022 United States, Connecticut ... More >> UConn Health Not yet recruiting Farmington, Connecticut, United States, 06030 Less <<
NCT02051309 Smoking Cessation Phase 2 Active, not recruiting November 2019 United States, Connecticut ... More >> Yale Center for Clinical Investigations, Yale University New Haven, Connecticut, United States, 06519 Less <<
NCT01081132 - Completed - -
NCT03137082 Alcohol Abstinence Phase 1 Phase 2 Recruiting December 2019 United States, New York ... More >> The Clinical Research Center Recruiting East Setauket, New York, United States, 11794 Contact: Antoinette Funaro, MS    631-638-0057    antoinette.funaro@stonybrookmedicine.edu    Putnam Hall Outpatient Facility Recruiting Stony Brook, New York, United States, 11794 Contact: David Schlager, MD    631-444-2571    david.schlager@stonybrookmedicine.edu Less <<
NCT01467999 Cannabis Dependence Phase 1 Completed - United States, New York ... More >> STARS New York, New York, United States, 10032 Less <<
NCT01467999 - Completed - -
NCT03764098 Alcohol Use Disorder Phase 2 Not yet recruiting September 29, 2020 United States, Connecticut ... More >> Yale University School of Medicine Not yet recruiting New Haven, Connecticut, United States, 06519 Contact: Meaghan Lavery    203-737-2783    meaghan.lavery@yale.edu    Contact: Sabrina Coppola    203-737-2827    sabrina.coppola@yale.edu    Principal Investigator: Sherry McKee, PhD Less <<
NCT01904526 Smoking Phase 2 Completed - United States, Connecticut ... More >> Yale Center for Clinical Investigations, Yale University New Haven, Connecticut, United States, 06519 Less <<
NCT01709695 ADHD Attentio... More >>n Deficit Hyperactivity Disorder Less << Phase 4 Completed - United States, New York ... More >> Icahn School of Medicine at Mount Sinai New York, New York, United States, 10029 Less <<
NCT02141113 Adult Attention-Deficit Hypera... More >>ctivity Disorder Less << Phase 4 Completed - United States, Michigan ... More >> Rochester Center for Behavioral Medicine Rochester Hills, Michigan, United States, 48307 Less <<
NCT03662763 Attention Deficit Disorder Phase 3 Completed - Netherlands ... More >> Maastricht University Medical Centre Maastricht, Netherlands Less <<
NCT01904526 - Completed - -

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.54mL

0.71mL

0.35mL

17.70mL

3.54mL

1.77mL

35.39mL

7.08mL

3.54mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

Historical Records

Categories