Alternatived Products of [ 312-31-2 ]
Product Details of [ 312-31-2 ]
| CAS No. : | 312-31-2 |
MDL No. : | MFCD00054602 |
| Formula : |
C12H9FO2S
|
Boiling Point : |
- |
| Linear Structure Formula : | - |
InChI Key : | - |
| M.W : |
236.26
|
Pubchem ID : | - |
| Synonyms : |
|
Safety of [ 312-31-2 ]
| Signal Word: | |
Class: | |
| Precautionary Statements: | |
UN#: | |
| Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 312-31-2 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 312-31-2 ]
- 1
-
[ 824-80-6 ]
-
potassium phenyltrifluoborate
[ No CAS ]
-
[ 312-31-2 ]
| Yield | Reaction Conditions | Operation in experiment |
| 89% |
With copper(l) iodide; sodium acetate; In 1,2-dichloro-ethane; at 25℃; for 3h; |
General procedure: A mixture of potassium arylfluoborate (1 mmol), sodium aryl sulfinate (1 mmol), CuI (0.1 mmol), sodium acetate (1.2 mmol) and DCE (2 mL) was stirred at 25 C under air for 3 h. After filtration, the organic phases were evaporated under reduced pressure, and the residue was subjected to flash column chromatography [silica gel, ethyl acetate/petroleum ether (60-90 C) = 1/8] to obtain the desired product. |
- 2
-
[ 2266-41-3 ]
-
[ 98-80-6 ]
-
[ 312-31-2 ]
| Yield | Reaction Conditions | Operation in experiment |
| 66% |
With copper(II) acetate monohydrate In ethanol at 20℃; for 6h; |
General procedure for the coupling of aryl boronic acids and aryl sulfonylhydrazides
General procedure: Arylboronic acids (1.2 mmol), arylsulfonyl hydrazides (1.0mmol), cupric acetate (1.5 mmol), and EtOH (2.0 mL) were taken in a 25 mL two-neck flask. The reaction mixture was stirred at r.t. for 6 h in air. The solution was evaporated under reduced pressure and H2O (20 mL) was added, and then the mixture was extracted with EtOAc (4 10 mL). The extracts were combined and washed with brine (3 10 mL), dried over MgSO4, filtered, evaporated, and purified by chromatography on silica gel to obtain the desired products with EtOAc-hexane (v/v = 1:5 to 1:10). The products were characterized by their spectral and analytical data and compared with those of the known compounds. |
- 3
-
[ 640-60-8 ]
-
[ 824-80-6 ]
-
[ 312-31-2 ]
| Yield | Reaction Conditions | Operation in experiment |
| 86% |
With tetrakis(actonitrile)copper(I) hexafluorophosphate; In dimethyl sulfoxide; at 120℃; |
General procedure: A mixture of the sodium arylsulfinate (1 mmol), aryl tosylate (1 mmol), [Cu(CH3CN)4]PF6 (0.1 mmol) and DMSO (2 mL) was stirred at 120 C under air for 6 h. After wards, water (2 mL) was added to the reaction solution which was then filtered and the solution extracted by Et2O (3 × 2 mL). The organic phases were combined and evaporated under reduced pressure. The residue was purified on a SiO2 column to afford the desired product (eluent; ethyl acetate/hexane 1 : 15). |
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