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Chemical Structure| 330461-64-8 Chemical Structure| 330461-64-8

Structure of AK-1
CAS No.: 330461-64-8

Chemical Structure| 330461-64-8

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AK-1 is a cell permeable, benzylsulfonamide that inhibits SIRT2 activity (IC50= 12.5 µM through enzymatic assay) by targeting the SIRT2 nicotinamide binding site, but may also target SIRT1 and SIRT3 (IC50 >40 µM) with much less potency.

Synonyms: AK-1

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Product Details of AK-1

CAS No. :330461-64-8
Formula : C19H21N3O5S
M.W : 403.45
SMILES Code : O=C(NC1=CC=CC([N+]([O-])=O)=C1)C2=CC=CC(S(=O)(N3CCCCCC3)=O)=C2
Synonyms :
AK-1
MDL No. :MFCD01122550

Safety of AK-1

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H319
Precautionary Statements:P264-P280-P305+P351+P338-P337+P313

Related Pathways of AK-1

epigenetics

Isoform Comparison

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2.48mL

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12.39mL

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1.24mL

24.79mL

4.96mL

2.48mL

 

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