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Chemical Structure| 330785-90-5 Chemical Structure| 330785-90-5

Structure of BTK ligand 1
CAS No.: 330785-90-5

Chemical Structure| 330785-90-5

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Product Details of BTK ligand 1

CAS No. :330785-90-5
Formula : C22H22N6O
M.W : 386.45
SMILES Code : NC1=C2C(N(C3CCNCC3)N=C2C4=CC=C(OC5=CC=CC=C5)C=C4)=NC=N1
MDL No. :MFCD32173634

Safety of BTK ligand 1

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P403+P233-P405-P501

Isoform Comparison

Biological Activity

Description
BTK ligand 1 is a ligand designed to target Bruton’s tyrosine kinase (Btk), enabling its combination with E3 ligase ligand (Ligand for E3 Ligase) through a PROTAC linker to form PROTAC. Such PROTACs, targeting Btk, find utility in the study of chronic lymphocytic leukemia (CLL) and other B-cell malignancies[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.59mL

0.52mL

0.26mL

12.94mL

2.59mL

1.29mL

25.88mL

5.18mL

2.59mL

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