[ CAS No. 342639-96-7 ]

{[proInfo.proName]}

Quality Control

Purity: {[proInfo.showProBatch.pb_purity]}

Related Doc.

SDS

Product Details

CAS No. :342639-96-7MDL No. :MFCD30182306
Formula :C13H12N6O2InChI Key :NDJJEQIMIJJCLL-UHFFFAOYSA-N
M.W :284.27Pubchem ID :69894253
Boiling Point :-
Synonyms :

Computed Properties

TPSA : 111 H-Bond Acceptor Count : 6
XLogP3 : 3.1 H-Bond Donor Count : 3
SP3 : 0.08 Rotatable Bond Count : 3

Safety

Signal Word:WarningClassN/A
Precautionary Statements:P261-P305+P351+P338UN#:N/A
Hazard Statements:H302-H315-H319-H335Packing Group:N/A
GHS Pictogram:

Application In Synthesis

[ 342639-96-7 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 342639-94-5 ]
  • [ 74-89-5 ]
  • [ 342639-96-7 ]
YieldReaction ConditionsOperation in experiment
82%
Stage #1: at 25℃; for 1.00 h;
Stage #2: With water In methanol for 1.00 h;
EXAMPLE 3
Preparation of 2-(1H-5-indazolylamino)-6-methyl amino-3-nitropyridine
To the solution of methanol with 40percent methylamine (20 ml) was added 2-(1H-5-indazolylamino)-6-methoxy-3-nitropyridine (1 g) obtained by the example 1, and the solution was reacted at 25° C. for 1 hr..
The reaction mixture was added H2O (20 ml) slowly and stirred for 1 hr..
The reaction mixture was filtered, washed with 30percent aqueous methanol solution (5 ml) and then obtained a solid product..
The solid product was dried at 50-60° C. in vacuo to obtain the desired compound (0.82 g, 82percent).
[00070] m.p.: 238240° C. [00071] 1H-NMR (DMSO-d6), ppm: δ 2.86(d, 3H), 6.09(d, 1H), 7.51(d, 1H), 7.57 (d, 1H), 8.05(t, 2H), 8.24 (d, 2H),10.97(s, 1H), 13.05 (br s, 1H)
Reference: [1] Patent: US6743795, 2004, B1. Location in patent: Page/Page column 8
Related Products
Historical Records