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Quality Control of [ 3731-59-7 ]

COA NMR CNMR HPLC LC-MS

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SDS Specification

Alternatived Products of [ 3731-59-7 ]

Product Details of [ 3731-59-7 ]

CAS No. :	3731-59-7	MDL No. :	MFCD00460678
Formula :	C₆H₁₃N₅O	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	-
M.W :	171.20	Pubchem ID :	-
Synonyms :

Safety of [ 3731-59-7 ]

Signal Word:	Warning	Class:
Precautionary Statements:	P261-P280-P301+P312-P302+P352-P305+P351+P338	UN#:
Hazard Statements:	H302-H315-H319-H335	Packing Group:
GHS Pictogram:

Application In Synthesis of [ 3731-59-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 3731-59-7 ]

[ 3731-59-7 ] Synthesis Path-Downstream 1~38

1
[ 10024-89-2 ]
[ 461-58-5 ]
[ 3731-59-7 ]

Yield	Reaction Conditions	Operation in experiment
	at 130 - 150℃;
	In butan-1-ol for 6h; Reflux;

Reference： [1]Shapiro et al. [Journal of the American Chemical Society, 1959, vol. 81, p. 3725,3726]
[2]Location in patent: scheme or table Sachdeva, Nikhil; Dolzhenko, Anton V.; Keung Chui, Wai [Organic and Biomolecular Chemistry, 2012, vol. 10, # 23, p. 4586 - 4596]

2
[ 110-78-1 ]
[ 3731-59-7 ]
[ 58248-17-2 ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide

Reference： [1]El Kerdawy; Selim [Pharmazie, 1975, vol. 30, # 12, p. 768 - 770]

3
[ 542-85-8 ]
[ 3731-59-7 ]
[ 58248-22-9 ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide

Reference： [1]El Kerdawy; Selim [Pharmazie, 1975, vol. 30, # 12, p. 768 - 770]

4
[ 628-30-8 ]
[ 3731-59-7 ]
[ 58248-23-0 ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide

Reference： [1]El Kerdawy; Selim [Pharmazie, 1975, vol. 30, # 12, p. 768 - 770]

5
[ 3731-59-7 ]
[ 622-78-6 ]
[ 58248-25-2 ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide

Reference： [1]El Kerdawy; Selim [Pharmazie, 1975, vol. 30, # 12, p. 768 - 770]

6
[ 3731-59-7 ]
[ CAS Unavailable ]
[ 58248-19-4 ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide

Reference： [1]El Kerdawy; Selim [Pharmazie, 1975, vol. 30, # 12, p. 768 - 770]

7
[ 3731-59-7 ]
[ 107-99-3 ]
[ 58248-40-1 ]

Yield	Reaction Conditions	Operation in experiment
	With pyridine

Reference： [1]El Kerdawy; Selim [Pharmazie, 1975, vol. 30, # 12, p. 768 - 770]

8
[ 3731-59-7 ]
[ 109-54-6 ]
[ 58248-42-3 ]

Yield	Reaction Conditions	Operation in experiment
	With pyridine

Reference： [1]El Kerdawy; Selim [Pharmazie, 1975, vol. 30, # 12, p. 768 - 770]

9
[ 3731-59-7 ]
[ 100-35-6 ]
[ 58248-41-2 ]

Yield	Reaction Conditions	Operation in experiment
	With pyridine

Reference： [1]El Kerdawy; Selim [Pharmazie, 1975, vol. 30, # 12, p. 768 - 770]

10
[ 3731-59-7 ]
[ 556-61-6 ]
[ 58248-21-8 ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide

Reference： [1]El Kerdawy; Selim [Pharmazie, 1975, vol. 30, # 12, p. 768 - 770]

11
[ 3731-59-7 ]
[ 134-81-6 ]
[ 36092-20-3 ]

Yield	Reaction Conditions	Operation in experiment
	With sodium ethanolate

Reference： [1]Furukawa,M. et al. [Chemical and pharmaceutical bulletin, 1972, vol. 20, p. 521 - 525]

12
[ 3731-59-7 ]
[ CAS Unavailable ]
[ 58248-16-1 ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide

Reference： [1]El Kerdawy; Selim [Pharmazie, 1975, vol. 30, # 12, p. 768 - 770]

13
[ 3731-59-7 ]
[ 57-06-7 ]
[ 58248-26-3 ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide

Reference： [1]El Kerdawy; Selim [Pharmazie, 1975, vol. 30, # 12, p. 768 - 770]

14
[ 3731-59-7 ]
[ 111-36-4 ]
[ 58248-18-3 ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide

Reference： [1]El Kerdawy; Selim [Pharmazie, 1975, vol. 30, # 12, p. 768 - 770]

15
[ 96-49-1 ]
[ 3731-59-7 ]
[ 2045-26-3 ]

Yield	Reaction Conditions	Operation in experiment
47%	In N,N-dimethyl-formamide for 96h; Ambient temperature;

Reference： [1]Kihara, Yoshito; Kabashima, Shigeru; Yamasaki, Tetsuo; Ohkawara, Tadashi; Furukawa, Mitsuru [Journal of Heterocyclic Chemistry, 1990, vol. 27, # 5, p. 1213 - 1216]

16
[ 2094-73-7 ]
[ 3731-59-7 ]
2-amino-4-(tricyclo<3.3.1.1^3,7>decyl-1)-6-morpholino-1,3,5-triazine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
60%	With sodium methylate In methanol a) 0 deg C, 30 min, b) RT, 2 d, c) 35 deg C, 4 d;

Reference： [1]Tsitsa; Antoniadou-Vyza; Hamodrakas; Eliopoulos; Tsantili-Kakoulidou; Lada-Hytiroglou; Roussakis; Chinou; Hempel; Camerman; Ottensmeyer; Vanden Berghe [European Journal of Medicinal Chemistry, 1993, vol. 28, # 2, p. 149 - 158]

17
[ 3731-59-7 ]
[ 38922-77-9 ]
[ 115854-26-7 ]

Yield	Reaction Conditions	Operation in experiment
30%	With sodium methylate In methanol 1.) r.t., 2.) reflux;

Reference： [1]Kosary; Kasztreiner; Rabloczky; Kurthy [European Journal of Medicinal Chemistry, 1989, vol. 24, # 1, p. 97 - 99]

18
[ 3731-59-7 ]
[ 123531-52-2 ]
[ 115854-33-6 ]

Reference： [1]European Journal of Medicinal Chemistry,1989,vol. 24,p. 97 - 99

19
[ 19747-79-6 ]
[ 3731-59-7 ]
[ 169788-42-5 ]

Yield	Reaction Conditions	Operation in experiment
80%	In ethanol Heating;

Reference： [1]Kelarev, V. I.; Koshelev, V. N.; Morozova, G. V.; Karakhanov, R. A.; Remizov, A. S. [Chemistry of Heterocyclic Compounds, 1995, vol. 31, # 2, p. 186 - 194][Khimiya Geterotsiklicheskikh Soedinenii, 1995, # 2, p. 214 - 223]

20
[ 18382-13-3 ]
[ 3731-59-7 ]
[ 169788-48-1 ]

Yield	Reaction Conditions	Operation in experiment
69%	In ethanol Heating;

21
[ 3731-59-7 ]
[ 151621-91-9 ]
[ 169788-45-8 ]

Yield	Reaction Conditions	Operation in experiment
82%	In ethanol Heating;

22
[ 3731-59-7 ]
[ 95792-63-5 ]
[ 201229-58-5 ]

Yield	Reaction Conditions	Operation in experiment
63%	In toluene Heating;

Reference： [1]Brzozowski, Zdzislaw [Acta poloniae pharmaceutica, 1998, vol. 55, # 1, p. 49 - 56]

23
[ 3731-59-7 ]
[ 105-39-5 ]
[ 21868-41-7 ]

Yield	Reaction Conditions	Operation in experiment
51%	In ethanol at 20℃; for 12h;

Reference： [1]Brzozowski; Saczewski; Gdaniec [European Journal of Medicinal Chemistry, 2000, vol. 35, # 12, p. 1053 - 1064]

24
[ 3731-59-7 ]
[ 105-56-6 ]
[ 886968-56-5 ]

Yield	Reaction Conditions	Operation in experiment
16%	In methanol at 20℃; for 3h;

Reference： [1]Saczewski; Bulakowska; Bednarski; Grunert [European Journal of Medicinal Chemistry, 2006, vol. 41, # 2, p. 219 - 225]

25
[ 3731-59-7 ]
[ 105-36-2 ]
[ 871332-14-8 ]

Yield	Reaction Conditions	Operation in experiment
39%	In methanol at 20℃; for 2.5h;

Reference： [1]Saczewski; Bulakowska [Polish Journal of Chemistry, 2005, vol. 79, # 4, p. 739 - 748]

26
[ 3731-59-7 ]
[ 871332-35-3 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: 39 percent / methanol / 2.5 h / 20 °C 2: 80 percent / dimethylformamide / 12 h / 20 °C 3: 38 percent / diethyl cyanophosphonate; triethylamine / dimethylformamide / 12 h / 20 °C 4: 80 percent / NaOH / tetrahydrofuran; H₂O / 4 h / 20 °C

Reference： [1]Saczewski; Bulakowska [Polish Journal of Chemistry, 2005, vol. 79, # 4, p. 739 - 748]

27
[ 3731-59-7 ]
[ CAS Unavailable ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 3 steps 1: 39 percent / methanol / 2.5 h / 20 °C 2: 80 percent / dimethylformamide / 12 h / 20 °C 3: 38 percent / diethyl cyanophosphonate; triethylamine / dimethylformamide / 12 h / 20 °C

Reference： [1]Saczewski; Bulakowska [Polish Journal of Chemistry, 2005, vol. 79, # 4, p. 739 - 748]

28
[ 3731-59-7 ]
[ 7537-63-5 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: 16 percent / methanol / 3 h / 20 °C 2: 27 percent / sodium carbonate / dimethylformamide; H₂O / Heating

Reference： [1]Saczewski; Bulakowska; Bednarski; Grunert [European Journal of Medicinal Chemistry, 2006, vol. 41, # 2, p. 219 - 225]

29
[ 3731-59-7 ]
[ 201229-95-0 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: 63 percent / toluene / Heating 2: 69 percent / NaOH, Na₂CO₃ / H₂O / 6 h / 40 - 85 °C

Reference： [1]Brzozowski, Zdzislaw [Acta poloniae pharmaceutica, 1998, vol. 55, # 1, p. 49 - 56]

30
[ 3731-59-7 ]
[ CAS Unavailable ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: 63 percent / toluene / Heating 2: 81 percent / DMSO / 10 h / 90 °C

Reference： [1]Brzozowski, Zdzislaw [Acta poloniae pharmaceutica, 1998, vol. 55, # 1, p. 49 - 56]

31
[ 3731-59-7 ]
[ 724692-34-6 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: NaOEt 2: aq. HCl

Reference： [1]Furukawa,M. et al. [Chemical and pharmaceutical bulletin, 1972, vol. 20, p. 521 - 525]

32
[ 110-91-8 ]
[ 461-58-5 ]
[ 3731-59-7 ]

Yield	Reaction Conditions	Operation in experiment
22%	Stage #1: morpholine; N-Cyanoguanidine In toluene at 20℃; for 0.25h; Stage #2: With hydrogenchloride In water; toluene for 7h;	2.2. General Procedure for the Synthesis of Compounds 1-10. General procedure: To a solution of dicyandiamide (0.5 g, 0.0060 mol) intoluene (5 mL) was added 1.1 mol equiv of correspondingalkylamines - or arylamines -. After the reactionmixture was stirred at room temperature for 15min, amixture 50 : 50 of HCl diluted in water (2.5 mL) was addeddropwise. This mixture was stirred at reflux for 3 to 16 h.After that, the obtained residuewas neutralizedwith a dilutedsolution of NH4OH. Solvent was removed under vacuum,and the residues were washed with water. The crude solidproducts were then recrystallized from ethanol affording titlecompounds (Figure 2, Table 1).
	In 1,4-dioxane at 90℃; for 0.25h; Microwave irradiation;

Reference： [1]Gutierrez-Lara, Erika; Martínez-Conde, Carlos; Rosales-Ortega, Edgar; Ramírez-Espinosa, Juan José; Rivera-Leyva, Julio C.; Centurión, David; Carvajal, Karla; Ortega-Cuellar, Daniel; Estrada-Soto, Samuel; Navarrete-Vázquez, Gabriel [Journal of Chemistry, 2017, vol. 2017]
[2]Location in patent: scheme or table Dao, Pascal; Garbay, Christiane; Chen, Huixiong [Tetrahedron, 2012, vol. 68, # 20, p. 3856 - 3860]

33
[ 3731-59-7 ]
[ 1381874-51-6 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: sodium hydroxide / water / 12 h / 20 °C 2: acetic acid / Reflux; Inert atmosphere

Reference： [1]Sachdeva, Nikhil; Dolzhenko, Anton V.; Keung Chui, Wai [Organic and Biomolecular Chemistry, 2012, vol. 10, # 23, p. 4586 - 4596]

34
[ 3731-59-7 ]
[ 141-97-9 ]
[ 55474-80-1 ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydroxide In water at 20℃; for 12h;

Reference： [1]Location in patent: experimental part Sachdeva, Nikhil; Dolzhenko, Anton V.; Keung Chui, Wai [Organic and Biomolecular Chemistry, 2012, vol. 10, # 23, p. 4586 - 4596]

35
[ 1993443-78-9 ]
[ 3731-59-7 ]
[ 2074651-74-2 ]

Yield	Reaction Conditions	Operation in experiment
52.39 mg	In methanol at 20℃; for 24h;	23 Example 23UA-Gua synthesis, structure such as the formula XVIII, chemical name:(1S, 2R, 4aS, 6aS, 6bR, 12aR) -10-hydroxy-N- (imino (morpholino) methyl) carbamimidoyl) -1,2,6a, 6b, 9,9,12a-heptamethyl-1 , 3,4,5,6,6a, 6b, 7,8,8a, 9,10,11,12,12a, 12b, 13,14b-octadecahydropicene-4a (2H) -Carboxamide At room temperature, 200 mg of UA and 181 mg of DCC were dissolved with 3 ml of THF;The reaction flask was added dropwise to 101 mg of NHS dissolved in 1.7 ml of acetonitrile in an ice bath.The reaction was stirred at room temperature for 24 h. After the reaction was complete, the insoluble matter was removed by filtration, the solvent was distilled off under reduced pressure,Column column was activated after purification of UA. Take 100 mg of activated UA pure and53.47mg of Gua with 5 ml of methanol stirring dissolved at room temperature for 24 h,The solvent was evaporated under reduced pressure and the column was purified by UA-Gua (52.39 mg) in a yield of 47.6%.

Reference： [1]Current Patent Assignee: FUZHOU UNIVERSITY - CN106362157, 2017, A Location in patent: Paragraph 0076; 0077

36
[ CAS Unavailable ]
[ 3731-59-7 ]
[ CAS Unavailable ]

Yield	Reaction Conditions	Operation in experiment
51.32 mg	In methanol at 20℃; for 24h;	24 Example 24(9aR, 6bS, 8aS, 11R, 12S, 14bR) -8a - ((N- (imino (morpholino) methyl) carbamimidoyl) carbamoyl) -4, the structure of UA1-Gua, 4, 6a, 6b, 11, 12, 14b-Heptamethyl-1,2,3,4,4a, 5,6,6a, 6b, 7,8,8a, 9,10,11,12,12a, 14,14a, 14b-Icosahydropicen-3-yl acetate At room temperature, 200 mg of UA1 and 170.9 mg of DCC were dissolved with 3 ml of THF;The reaction flask was added dropwise to an ice bath with 95.4 mg of NHS dissolved in advance with 1.7 ml of acetonitrile.Stirring at room temperature for 24 h, until the UA1 reaction is complete, the filter to remove insoluble,The solvent was distilled off under reduced pressure, and the column was subjected to pure UA1. After 100 mg of activated UA1 and 51.11 mg of Gua were stirred with 5 ml of methanol and reacted at room temperature for 24 h,The solvent was evaporated under reduced pressure and the column was purified to give pure UA1-Gua (51.32 mg) in a yield of 46.8%.

Reference： [1]Current Patent Assignee: FUZHOU UNIVERSITY - CN106362157, 2017, A Location in patent: Paragraph 0079; 0080

37
[ CAS Unavailable ]
[ 3731-59-7 ]
[ 2074651-76-4 ]

Yield	Reaction Conditions	Operation in experiment
53.32 mg	In methanol at 20℃; for 24h;	25 Example 25UA2-Gua synthesis, structure as shown in XX, chemical name: (1S, 2R, 4aS, 6aS, 6bR, 12aR) -N- (N- (iminoMorpholino methyl) carbamimidoyl-1,2,6a, 6b, 9,9,12a-heptamethyl-10-oxo-1,3,4,5,6,6a, 6b, 7,8,8a, 10, 11, 12, 12a, 12b, 13, 14b-octadecahydropicene-4a (2H) -Carboxamide At room temperature, 200 mg of UA2 and 181.5 mg of DCC were dissolved with 3 ml of THF;The reaction flask was charged with 101.3 mg of NHS dissolved in advance with 1.7 ml of acetonitrile on an ice bath.Stirring at room temperature for 24 h, until the UA2 reaction is complete, the filter to remove insoluble,The solvent was distilled off under reduced pressure and the column was purified to produce UA2 pure product. Take 100 mg of activated UA2 and 53.71 mgOf Gua with 5 ml of methanol stirring dissolved at room temperature for 24 h, the solvent was evaporated under reduced pressure,The column was precipitated with UA2-Gua (53.32 mg) in a yield of 48.4%.

Reference： [1]Current Patent Assignee: FUZHOU UNIVERSITY - CN106362157, 2017, A Location in patent: Paragraph 0082; 0083

38
[ CAS Unavailable ]
[ 3731-59-7 ]
[ CAS Unavailable ]

Yield	Reaction Conditions	Operation in experiment
55.07 mg	In methanol at 20℃; for 24h;	20 Example 20UA3-Mor synthesis, structure as shown in XV, chemical name:(6aR, 6bS, 8aS, 11R, 12S, 14bR) -8a - ((N- (2- (azocan-1-yl) ethyl) carbamimidoyl) carbamoyl) -4,4,6a, 6b, 11,12,14b -heptamethyl-1,2,3,4,4a, 5,6,6a, 6b, 7,8,8a, 9,10,11,12,12a, 14,14a, 14b-icosahydropicen-3-yl 2,2-dichloroacetate At room temperature, 200 mg of UA3 and 145.63 mg of DCC were dissolved with 3 ml of THF;The reaction flask was added dropwise to an ice bath with 81.29 mg of NHS dissolved in advance with 1.7 ml of acetonitrile.The reaction was stirred at room temperature for 24 h. After the reaction of UA3 was complete, the insoluble matter was removed by filtration, the solvent was evaporated under reduced pressure,The column was precipitated after the UA3 was purified. Take 100 mg of activated UA3 pure and31.62 mg of Mor was stirred with 5 ml of methanol and reacted at room temperature for 24 h,The solvent was evaporated under reduced pressure and the column was chromatographed to give pure UA3-Mor (55.07 mg) in a yield of 48.2%.

Reference： [1]Current Patent Assignee: FUZHOU UNIVERSITY - CN106362157, 2017, A Location in patent: Paragraph 0067; 0068

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Prevention
Code	Phrase
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P221	Take any precaution to avoid mixing with combustibles
P222	Do not allow contact with air.
P223	Keep away from any possible contact with water, because of violent reaction and possible flash fire.
P230	Keep wetted
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Code	Phrase
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P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 3731-59-7 ] {[proInfo.proName]}

Quality Control of [ 3731-59-7 ]

Related Doc. of [ 3731-59-7 ]

Product Details of [ 3731-59-7 ]

Safety of [ 3731-59-7 ]

Application In Synthesis of [ 3731-59-7 ]

[ 3731-59-7 ] Synthesis Path-Downstream 1~38

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry