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Chemical Structure| 3782-00-1 Chemical Structure| 3782-00-1

Structure of 3782-00-1

Chemical Structure| 3782-00-1

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Product Details of [ 3782-00-1 ]

CAS No. :3782-00-1
Formula : C10H10O
M.W : 146.19
SMILES Code : CC1=C(C)C2=C(O1)C=CC=C2
MDL No. :MFCD00078708
InChI Key :YGBXXWTZWLALGR-UHFFFAOYSA-N
Pubchem ID :2734646

Safety of [ 3782-00-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 3782-00-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3782-00-1 ]

[ 3782-00-1 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 4265-25-2 ]
  • [ 3782-00-1 ]
  • 2
  • [ 513-86-0 ]
  • [ 5077-67-8 ]
  • [ 116-09-6 ]
  • [ 108-95-2 ]
  • [ 3131-63-3 ]
  • [ 3782-00-1 ]
  • [ 4265-25-2 ]
YieldReaction ConditionsOperation in experiment
8percent Mo on gamma-alumina containing 1-2percent dispersed silica; at 145℃; for 2h;Conversion of starting material; [0032] A feed containing 990 ppm hydroacetone (HA or acetol), 520 ppm of 1-hydroxy-2-butanone (1HB), and 490 ppm of 3-hydroxy-2-butanone (3HB or acetoin), was prepared from pure phenol and contacted for 2 hours at 145° C. with an alumina catalyst containing approximately 8 percent molybdenum. The catalyst was previously activated and dried. Conversion of hydroxyketones averaged 98, 98, and 100 percent for HA, 1HB, and 3HB, respectively, for three separate experiments. Approximately 6 percent of the HA was converted to 2-methyl benzofuran, 3 percent of the 1-HB was converted to 2-ethyl benzofuran, and 3 percent of 3-HB was converted to 1,3-dimethyl benzofuran.
gamma-alumina Containing 1-2percent Dispersed Silica; at 145℃; for 2h;Conversion of starting material; [0034] A feed containing 990 ppm HA, 520 ppm of 1HB, and 490 ppm of 3HB was prepared from pure phenol and contacted for 2 hours at 145° C. with an alumina catalyst containing no molybdenum and which had been previously activated and dried. Conversion of hydroxyketones were 18, 15, and 8 percent for HA, 1HB, and 3HB, respectively. The corresponding benzofuran selectivities were approximately 2, 0.5, and 2 percent.
4percent Mo on gamma-alumina Containing 1-2percent Dispersed Silica; at 145℃; for 2h;Conversion of starting material; [0033] A feed containing 990 ppm hydroacetone (HA or acetol), 520 ppm of 1-hydroxy-2-butanone (1HB), and 490 ppm 3-hydroxy-2-butanone (3HB or acetoin), was prepared from pure phenol and contacted for 2 hours at 145° C. with an alumina catalyst containing approximately 4 percent molybdenum. The catalyst was previously activated and dried. Conversion of hydroxyketones averaged 84, 87 and 98 percent for HA, 1HB, and 3HB, respectively, for three separate experiments. The corresponding benzofuran selectivities averaged approximately 6, 3, and 2.5 percent.
at 145℃; for 2h;Conversion of starting material; [0035] A feed containing 990 ppm HA, 520 ppm of 1HB and 490 ppm of 3HB was prepared from pure phenol and heated for 2 hours at 145° C. without addition of a catalyst. Conversion of hydroxyketones averaged 5, 5, and 7 percent for HA, 1HB, and 3HB, respectively, for three separate experiments. The corresponding benzofuran selectivities averaged approximately 3, 0.1, and 3 percent.
at 145℃; for 2h;Conversion of starting material; A feed containing 990 ppm hydroacetone (HA or acetol), 520 ppm of 1-hydroxy-2-butanone (1HB), and 490 ppm of 3- HYDROXY-2-BUTANONE (3HB or acetoin), was prepared from pure phenol and contacted for 2 hours at 145 C with an alumina catalyst containing approximately 8 percent molybdenum. The catalyst was previously activated and dried. Conversion of hydroxyketones averaged 98,98, and 100 percent for HA, 1HB, and 3HB, respectively, for three separate experiments. Approximately 6 percent of the HA was converted to 2-methyl benzofuran, 3 percent of the 1-HB was converted to 2-ethyl benzofuran, and 3 percent of 3-HB was converted to 1,3- dimethyl benzofuran.
aluminum oxide; at 145℃; for 2h;Conversion of starting material; A feed containing 990 ppm HA, 520 ppm of 1HB, and 490 ppm of 3HB was prepared from pure phenol and contacted for 2 hours at 145 C with an alumina catalyst containing no molybdenum and which had been previously activated and dried. Conversion of hydroxyketones were 18,15, and 8 percent for HA, 1HB, and 3HB, respectively. The corresponding benzofuran selectivities were approximately 2,0. 5, and 2 percent.
at 145℃; for 2h;Conversion of starting material; A feed containing 990 ppm hydroacetone (HA or acetol), 520 ppm of 1-hydroxy-2-butanone (1HB), and 490 ppm 3-hydroxy- 2-butanone (3HB or acetoin), was prepared from pure phenol and contacted for 2 hours at 145°C with an alumina catalyst containing approximately 4 percent molybdenum. The catalyst was previously activated and dried. Conversion of hydroxyketones averaged 84,87 and 98 percent for HA, 1HB, and 3HB, respectively, for three separate experiments. The corresponding benzofuran selectivities averaged approximately 6,3, and 2.5 percent.
at 145℃; for 2h;Conversion of starting material; A feed containing 990 ppm HA, 520 ppm of 1HB and 490 ppm of 3HB was prepared from pure phenol and heated for 2 hours at 145 C without addition of a catalyst. Conversion of hydroxyketones averaged 5,5, and 7 percent for HA, 1HB, and 3HB, respectively, for three separate experiments. The corresponding benzofuran selectivities averaged approximately 3,0. 1, and 3 percent.

  • 3
  • [ 513-86-0 ]
  • [ 5077-67-8 ]
  • [ 116-09-6 ]
  • [ 3131-63-3 ]
  • [ 3782-00-1 ]
  • [ 4265-25-2 ]
YieldReaction ConditionsOperation in experiment
amberlyst 15 (TM) cation exchange resin; at 80℃; for 2h;Conversion of starting material; [0046] A feed containing 1450 ppm hydroxyacetone (HA or acetol), 520 ppm of 1-hydroxy-2-butanone (1HB), and 540 ppm of 3-hydroxy-2-butanone (3HB or acetoin) was prepared from pure phenol. The feed was stirred for 2 hours at 80° C. with Amberlyst 15 (TM) cation exchange resin beads which had previously been water rinsed and vacuum dried. Conversion of the hydroxyketones was 94 percent for HA, 74 percent for 1HB, and 80 percent for 3HB. Approximately 6 percent of the HA was converted to 2-MBF (2-methyl benzofuran), 3 percent of the 1HB was converted to EBF (2-ethyl benzofuran), and 24 percent of the 3HB was converted to DMBF (1,3 dimethyl benzofuran).
Y-zeolite catalyst; at 150℃; for 2h;Conversion of starting material; [0047] A feed containing 1000 ppm HA, 5300 ppm of 1HB, and 1050 ppm of 3HB was prepared from pure phenol and contacted for 2 hours at 150° C. with a Y-zeolite catalyst which had been previously activated and dried. The percent conversions of hydroxyketones were 93 for HA, 84 for 1HB, and 89 for 3HB. The corresponding benzofuran selectives were 33, 18 and 68 percent.
alumina catalyst containing approximately 4 percent molybdenum; at 145℃; for 2h;Conversion of starting material; [0049] A feed containing 990 ppm HA, 520 ppm of 1HB, and 490 ppm 3HB was prepared from pure phenol and contacted for 2 hours at 145° C. with an alumina catalyst containing approximately 4 percent molybdenum. The catalyst was previously activated and dried. Conversion of hydroxyketones were 84, 87 and 98 percent for HA, 1HB, and 3HB. The corresponding benzofuran selectivities averaged approximately 6, 3, and 2.5 percent.
alumina catalyst containing approximately 8 percent molybdenum; at 145℃; for 2h;Conversion of starting material; [0048] A feed containing 990 ppm HA, 520 ppm of 1HB, and 490 ppm of 3HB was prepared from pure phenol and contacted for 2 hours at 145° C. with an alumina catalyst containing approximately 8 percent molybdenum. The catalyst was previously activated and dried. Conversion of hydroxyketones averaged 98, 98, and 100 percent for HA, 1HB, and 3HB, respectively, for three separate experiments. The corresponding benzofuran selectivities averaged approximately 6, 3, and 3 percent
[0050] A feed containing 990 ppm HA, 520 ppm of 1HB, and 490 ppm of 3HB was prepared from pure phenol and contacted for 2 hours at 145° C. with an alumina catalyst containing no molybdenum and which had been previously activated and dried. Conversion of hydroxyketones averaged 18, 15, and 8 percent for HA, 1HB, and 3HB, respectively, for three separate experiments. The corresponding benzofuran selectivities were approximately 2, 0.5, and 2 percent.
Conversion of starting material; [0051] A feed containing 990 ppm HA, 520 ppm of 1HB and 490 ppm of 3HB was prepared from pure phenol and heated for 2 hours at 145° C. without addition of a catalyst. Conversion of hydroxyketones averaged 5, 5, and 7 percent for HA, 1HB, and 3HB, respectively, for three separate experiments. The corresponding benzofuran selectivities averaged approximately 3, 0.1, and 3 percent.

 

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