Purity | Size | Price | VIP Price | USA Stock *0-1 Day | Global Stock *5-7 Days | Quantity | |||||
{[ item.p_purity ]} | {[ item.pr_size ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} | {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]} | {[ item.pr_usastock ]} | Inquiry - | {[ item.pr_chinastock ]} | Inquiry - |
*Storage: {[proInfo.prStorage]}
CAS No. : | 405057-75-2 | MDL No. : | MFCD07772081 |
Formula : | C14H20N2O2 | Boiling Point : | 374.6±42.0°C at 760 mmHg |
Linear Structure Formula : | - | InChI Key : | - |
M.W : | 248.32 | Pubchem ID : | 18621153 |
Synonyms : |
|
TPSA :Topological Polar Surface Area | 41.6 | H-Bond Acceptor Count : | 3 |
XLogP3 : | 1.7 | H-Bond Donor Count : | 1 |
SP3 : | 0.50 | Rotatable Bond Count : | 4 |
Signal Word: | Warning | Class: | N/A |
Precautionary Statements: | P261-P305+P351+P338 | UN#: | N/A |
Hazard Statements: | H302-H315-H319-H335 | Packing Group: | N/A |
GHS Pictogram: |
![]() |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
100% | Stage #1: With sodium tris(acetoxy)borohydride; acetic acid In 1,2-dichloro-ethane at 20℃; Stage #2: With sodium hydrogencarbonate In water; 1,2-dichloro-ethane |
To a suspension of 1-(benzyloxycarbonyl)piperidin-4-one (4 g, 17.16 mmol), methanamine hydrochloride (1.95 g, 18.88 mmol) and triacetoxy sodium borohydride (5.09 g, 24.02 mmol) in DCE (46 mL) was added HOAc (0.8 mL, 12.7 mmol), and the resulting mixture was stirred at room temperature overnight. The reaction mixture was treated with saturated aqueous NaHCO3 (50 mL) , extracted with CH2CI2 (3 X 40 mL), dried over Na2SO4, filtered, and concentrated in vacuo to give crude 1- (benzyloxycarbonyl)-4-methylaminopiperidine (4 g, 100percent): 1H NMR (400 MHz, CDCI3) δ ppm 7.31-7.35 (m, 5H), 5.12 (s, 2H), 4.13 (s, 2H), 3.72 (s, 3H), 2.86 (t, J = 10 Hz, 1 H), 2.56-2.63 (m, 1 H), 2.48 (s, 3H), 2.12 (s, 3H), 1.91 (s, 1 H), 1 .22-1.39 (m, 2H). |
[ 1159826-41-1 ]
Benzyl 4-aminopiperidine-1-carboxylate hydrochloride
Similarity: 0.97
[ 1044560-96-4 ]
(R)-Benzyl 3-aminopiperidine-1-carboxylate
Similarity: 0.92
[ 1159826-41-1 ]
Benzyl 4-aminopiperidine-1-carboxylate hydrochloride
Similarity: 0.97
[ 1001401-60-0 ]
(R)-Benzyl 5-methyl-1,4-diazepane-1-carboxylate
Similarity: 0.93
[ 1044560-96-4 ]
(R)-Benzyl 3-aminopiperidine-1-carboxylate
Similarity: 0.92
[ 1159826-41-1 ]
Benzyl 4-aminopiperidine-1-carboxylate hydrochloride
Similarity: 0.97
[ 1001401-60-0 ]
(R)-Benzyl 5-methyl-1,4-diazepane-1-carboxylate
Similarity: 0.93
[ 1044560-96-4 ]
(R)-Benzyl 3-aminopiperidine-1-carboxylate
Similarity: 0.92
[ 1159826-41-1 ]
Benzyl 4-aminopiperidine-1-carboxylate hydrochloride
Similarity: 0.97
[ 1044560-96-4 ]
(R)-Benzyl 3-aminopiperidine-1-carboxylate
Similarity: 0.92