Alternatived Products of [ 4431-83-8 ]
Product Details of [ 4431-83-8 ]
| CAS No. : | 4431-83-8 |
MDL No. : | MFCD00043945 |
| Formula : |
C7H16O4
|
Boiling Point : |
- |
| Linear Structure Formula : | - |
InChI Key : | QWRBKBNCFWPVJX-UHFFFAOYSA-N |
| M.W : |
164.20
|
Pubchem ID : | 78164 |
| Synonyms : |
|
Application In Synthesis of [ 4431-83-8 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Upstream synthesis route of [ 4431-83-8 ]
- Downstream synthetic route of [ 4431-83-8 ]
- 1
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[ 50-00-0 ]
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[ 109-86-4 ]
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[ 4431-83-8 ]
| Yield | Reaction Conditions | Operation in experiment |
| 94.4% |
With Amberlyst15 catalyst In water; toluene Reflux; |
1-8 Example Two
In a 1000 mL three-neck reaction flask, 30 g of paraformaldehyde, 193.2 g of 2-methoxyethanol, and 25 g of Amberlyst15 catalyst were added. 500 mL of toluene with water was added, and a water separator was added. The temperature was raised until toluene refluxed with water until no more water was formed. Reduce the temperature to room temperature, filter off the catalyst, evaporate toluene, and add 5 g of potassium carbonate to neutralize the catalyst, filter off potassium carbonate and otherSalt, add 75 mL × 2 double distilled water, and collect the oil phase after layering. The oil phase was dried with anhydrous magnesium sulfate, and then distilled under reduced pressure. A 100-101C fraction at a pressure of 24 mm Hg was collected to obtain 155 g of a product with a yield of 94.4%. |
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With iron(III) chloride bei langsamer Destillation; |
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With toluene-4-sulfonic acid In benzene Heating; |
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With toluene-4-sulfonic acid In toluene |
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With sulfuric acid beim Kochen; |
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Reference：
[1]Current Patent Assignee: SHENZHEN QIANHAI BOYANG RES INSTITUTE - CN110511124, 2019, A
Location in patent: Paragraph 0041-0056
[2]Current Patent Assignee: CELANESE CORP - US2036303, 1932, A
Current Patent Assignee: Celanese Corp.America - US2036304, 1932, A
[3]Sokolowski,A.; Burczyk,B.
[Polish Journal of Chemistry, 1979, vol. 53, p. 905 - 912]
[4]Ross,S.D. et al.
[Journal of the American Chemical Society, 1973, vol. 95, p. 2193 - 2198]
[5]Current Patent Assignee: Baggett, John L. - US2331367, 1943, A
- 2
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[ 4431-83-8 ]
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[ 107-16-4 ]
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[(2-methoxy-ethoxy)-methoxy]-acetonitrile
[ No CAS ]
| Yield | Reaction Conditions | Operation in experiment |
|
With sulfuric acid |
|
|
With sulfuric acid |
|
- 3
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[ 4431-83-8 ]
-
[ 41633-60-7 ]
| Yield | Reaction Conditions | Operation in experiment |
|
With sulfuric acid; sodium carbonate In ethylene glycol |
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- 4
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[ 627-27-0 ]
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[ 4431-83-8 ]
-
[ 1768-64-5 ]
- 5
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[ 627-27-0 ]
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[ 4431-83-8 ]
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[ 92826-98-7 ]
| Yield | Reaction Conditions | Operation in experiment |
| 93 % Chromat. |
With titanium tetrachloride In dichloromethane at 22℃; for 3h; |
|
- 6
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[ 75-11-6 ]
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[ 109-86-4 ]
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[ 4431-83-8 ]
| Yield | Reaction Conditions | Operation in experiment |
| 58% |
In benzene at 75℃; for 5h; effect of temperature, various catalysts, various dihalomethanes, further alcohols; |
|
- 7
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[ 4431-83-8 ]
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[ 928-97-2 ]
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[ 25999-33-1 ]
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[ 25999-40-0 ]
| Yield | Reaction Conditions | Operation in experiment |
|
With titanium tetrachloride In dichloromethane at 0℃; for 1h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; |
|
- 8
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[ 4431-83-8 ]
-
chlorodiphenylphosphonium tetrachloroaluminate
[ No CAS ]
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<(2-methyoxyethoxy)methyl>diphenylphosphine oxide
[ No CAS ]
| Yield | Reaction Conditions | Operation in experiment |
| 61% |
In diethyl ether for 1.5h; Heating; |
|
Reference：
[1]Chauzov, V. A.; Studnev, Yu. N.; Rudnitskaya, L. S.; Fokin, A. V.
[Journal of general chemistry of the USSR, 1986, vol. 56, p. 2259 - 2262][Zhurnal Obshchei Khimii, 1986, vol. 56, # 11, p. 2553 - 2557]
- 9
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[ 109-86-4 ]
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[ 3970-21-6 ]
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[ 4431-83-8 ]
| Yield | Reaction Conditions | Operation in experiment |
|
for 4h; Ambient temperature; |
|
- 10
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[ 216440-54-9 ]
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[ 4431-83-8 ]
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(4R,5R)-4,5-Bis-iodomethyl-[1,3]dioxolane
[ No CAS ]
| Yield | Reaction Conditions | Operation in experiment |
|
With sodium iodide 1.) acetone, reflux, overnight, 2.) 110 deg C, 0.05 mmHg; Multistep reaction. Title compound not separated from byproducts; |
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| Yield | Reaction Conditions | Operation in experiment |
|
saeurekatal. Hydrolyse; |
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Hydrolyse: k, T1/2; |
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| Yield | Reaction Conditions | Operation in experiment |
|
at 25℃; Hydrolysis; |
|
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at 35℃; Hydrolysis; |
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- 14
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[ 50-00-0 ]
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[ 109-86-4 ]
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[ 7664-93-9 ]
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[ 4431-83-8 ]
- 15
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[ 7719-09-7 ]
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[ 4431-83-8 ]
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[ 3970-21-6 ]
| Yield | Reaction Conditions | Operation in experiment |
| 70% |
With sulfur dioxide |
C.B COMPARISON EXAMPLE B (without dimethyl formamide)
COMPARISON EXAMPLE B (without dimethyl formamide) 200 g of bis(2-methoxyethoxy)methane (1.218 mol; Mr =164.21) are warmed to c. 45° C. With stirring, 147.8 g of thionyl chlorid (1.242 mol; Mr =118.97) are added dropwise over 2 hours. Stirring is continued for 2 hours at 85° C. In the course of the reaction, altogether 13 g of sulfur dioxide evolve. The composition of the reaction mixture is determined in an aliquot of the mixture. The net result is as follows: Separation of the reaction mixture by distillation can be effected only with great difficulty. Distillation under reduced pressure (c. 20 mbar) affords 165 mg of highly impure 1-chloromethoxy-2-methoxyethane (64% purity) yield: 70%. |
- 16
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[ 4431-83-8 ]
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[ 201230-82-2 ]
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[ 873-74-5 ]
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N-(4-cyanophenyl)-2,5,7,10-tetraoxadodecan-12-amide
[ No CAS ]
| Yield | Reaction Conditions | Operation in experiment |
| 71% |
With 4,4′-dimethyl-2,2′-bipyridine; di-tert-butyl peroxide; cobalt bis(acetylacetonate) at 120℃; Inert atmosphere; Autoclave; |
|
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