Home Cart 0 Sign in  

[ CAS No. 478832-05-2 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 478832-05-2
Chemical Structure| 478832-05-2
Structure of 478832-05-2 * Storage: {[proInfo.prStorage]}

Quality Control of [ 478832-05-2 ]

Related Doc. of [ 478832-05-2 ]

SDS
Alternatived Products of [ 478832-05-2 ]
Alternatived Products of [ 478832-05-2 ]

Product Details of [ 478832-05-2 ]

CAS No. :478832-05-2 MDL No. :MFCD09743237
Formula : C11H15ClN2O Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W :226.70 g/mol Pubchem ID :18541766
Synonyms :

Safety of [ 478832-05-2 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 478832-05-2 ]

  • Upstream synthesis route of [ 478832-05-2 ]
  • Downstream synthetic route of [ 478832-05-2 ]

[ 478832-05-2 ] Synthesis Path-Upstream   1~3

  • 1
  • [ 478832-03-0 ]
  • [ 478832-05-2 ]
YieldReaction ConditionsOperation in experiment
99% With hydrogenchloride In tetrahydrofuran; 1,4-dioxane at 20℃; In tetrahydrofuran (6 ml) was dissolved tert-butyl 1-benzyl-5-oxo-3-pyrrolidinylcarbamate (480 mg, 1.65 mmol), followed by adding thereto 4N-hydrogen chloride/dioxane (6.0 ml, 24 mmol), and the resulting mixture was stirred overnight at room temperature. After completion of the reaction, diethyl ether (35 ml) was added to the reaction solution, and the resulting mixture was stirred at room temperature for 30 minutes and the precipitate was collected by filtration. The precipitate was washed with diethyl ether and dried to obtain 4-amino-1-benzyl-2-pyrrolidinone hydrochloride (380 mg, 99percent).1H-NMR (DMSO-d6) δ; 2.23 (1H, dd, J=4.0, 17.2Hz), 2.76 (1H, dd, J=8.6, 17.2Hz), 3.22 (1H, dd, J=4.0, 10.8Hz), 3.53 (1H, dd, J=7.7, 10.8Hz), 3.89 (1H, bs), 4.30 (1H, d, J=15.0Hz), 4.45 (1H, d, J=15.0Hz), 7.30 (5H, m), 8.32 (2H, bs).
Reference: [1] Patent: EP1403255, 2004, A1, . Location in patent: Page 79
  • 2
  • [ 5733-86-8 ]
  • [ 478832-05-2 ]
Reference: [1] Patent: EP1403255, 2004, A1,
  • 3
  • [ 51535-00-3 ]
  • [ 478832-05-2 ]
Reference: [1] Patent: EP1403255, 2004, A1,
Historical Records

Related Functional Groups of
[ 478832-05-2 ]

Amines

Chemical Structure| 15809-19-5

[ 15809-19-5 ]

N-Benzyl-N,N-dimethyl-3-tetradecanamidopropan-1-aminium chloride

Similarity: 0.84

Chemical Structure| 30250-67-0

[ 30250-67-0 ]

2-(2-Aminoethyl)isoindoline-1,3-dione hydrochloride

Similarity: 0.76

Chemical Structure| 131852-54-5

[ 131852-54-5 ]

(S)-1-Benzylpyrrolidin-3-amine dihydrochloride

Similarity: 0.76

Chemical Structure| 114715-38-7

[ 114715-38-7 ]

(S)-1-Benzyl-3-aminopyrrolidine

Similarity: 0.73

Chemical Structure| 18471-40-4

[ 18471-40-4 ]

1-Benzylpyrrolidin-3-amine

Similarity: 0.73

Aryls

Chemical Structure| 55186-89-5

[ 55186-89-5 ]

1-Benzyl-1,4-diazepan-5-one

Similarity: 0.86

Chemical Structure| 15809-19-5

[ 15809-19-5 ]

N-Benzyl-N,N-dimethyl-3-tetradecanamidopropan-1-aminium chloride

Similarity: 0.84

Chemical Structure| 2142-06-5

[ 2142-06-5 ]

1-Benzylpyrrolidine-2,5-dione

Similarity: 0.84

Chemical Structure| 154195-30-9

[ 154195-30-9 ]

1-Benzylazepane-2,5-dione

Similarity: 0.81

Chemical Structure| 502653-18-1

[ 502653-18-1 ]

2-Phenyl-1-(piperazin-1-yl)ethanone hydrochloride

Similarity: 0.77

Amides

Chemical Structure| 55186-89-5

[ 55186-89-5 ]

1-Benzyl-1,4-diazepan-5-one

Similarity: 0.86

Chemical Structure| 15809-19-5

[ 15809-19-5 ]

N-Benzyl-N,N-dimethyl-3-tetradecanamidopropan-1-aminium chloride

Similarity: 0.84

Chemical Structure| 2142-06-5

[ 2142-06-5 ]

1-Benzylpyrrolidine-2,5-dione

Similarity: 0.84

Chemical Structure| 154195-30-9

[ 154195-30-9 ]

1-Benzylazepane-2,5-dione

Similarity: 0.81

Chemical Structure| 1381795-31-8

[ 1381795-31-8 ]

(R)-2-(Piperidin-3-yl)isoindoline-1,3-dione hydrochloride

Similarity: 0.78

Related Parent Nucleus of
[ 478832-05-2 ]

Pyrrolidines

Chemical Structure| 2142-06-5

[ 2142-06-5 ]

1-Benzylpyrrolidine-2,5-dione

Similarity: 0.84

Chemical Structure| 131852-54-5

[ 131852-54-5 ]

(S)-1-Benzylpyrrolidin-3-amine dihydrochloride

Similarity: 0.76

Chemical Structure| 114715-38-7

[ 114715-38-7 ]

(S)-1-Benzyl-3-aminopyrrolidine

Similarity: 0.73

Chemical Structure| 18471-40-4

[ 18471-40-4 ]

1-Benzylpyrrolidin-3-amine

Similarity: 0.73

Chemical Structure| 1235437-44-1

[ 1235437-44-1 ]

(R)-1-Benzyl-N,N-dimethylpyrrolidin-3-amine

Similarity: 0.72