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Chemical Structure| 482-35-9 Chemical Structure| 482-35-9

Structure of Isoquercetin
CAS No.: 482-35-9

Chemical Structure| 482-35-9

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Isoquercitrinis can inhibit Wnt/β-catenin and activate the mitogen-activated protein kinase (MAPK) signalling pathway. It is a natural product isolated and purified from the herbs of Prunella vulgaris L. with a good effect of expectorant, cough, asthma and anti-tumoral activity.

Synonyms: Quercetin 3-glucoside; NSC 115918; Quercetin 3-O-glucoside

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Product Details of Isoquercetin

CAS No. :482-35-9
Formula : C21H20O12
M.W : 464.38
SMILES Code : O=C1C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)=C(C3=CC=C(O)C(O)=C3)OC4=C1C(O)=CC(O)=C4
Synonyms :
Quercetin 3-glucoside; NSC 115918; Quercetin 3-O-glucoside
MDL No. :MFCD00017746
InChI Key :OVSQVDMCBVZWGM-QSOFNFLRSA-N
Pubchem ID :5280804

Safety of Isoquercetin

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT01691404 Hypertension ... More >>Endothelial Dysfunction Less << Not Applicable Completed - Netherlands ... More >> Wageningen University Wageningen, Netherlands, 6703 HD Less <<
NCT02195232 Thromboembolism of Vein VTE in... More >> Colorectal Cancer|Thromboembolism of Vein in Pancreatic Cancer|Thromboembolism of Vein in Non-small Cell Lung Cancer Less << PHASE2|PHASE3 COMPLETED 2019-10-22 USC/Norris Comprehensive Cance... More >>r Center, Los Angeles, California, 90033, United States|VA Northern California Health Care System, Sacramento, California, 95655, United States|VA Connecticut Healthcare System, West Haven, Connecticut, 06450, United States|Veterans Affair Medical Center, Washington, District of Columbia, 20422, United States|York Hospital-Oncology Treatment Center, York, Maine, 03909, United States|Boston VA Healthcare System, Boston, Massachusetts, 02130, United States|Beth Israel Deaconess Medical Center, Boston, Massachusetts, 02215, United States|Mount Auburn Hospital, Waltham, Massachusetts, 02138, United States|Washington University in St. Louis, Saint Louis, Missouri, 63110, United States|Providence VA Medical Center, Providence, Rhode Island, 02908, United States|White River Junction VA Medical Center, White River Junction, Vermont, 05009, United States Less <<
NCT02818699 Overweight Ob... More >>ese Less << Not Applicable Recruiting January 2018 United States, Massachusetts ... More >> Human Nutrition Research Center on Aging at Tufts University Recruiting Boston, Massachusetts, United States, 02111 Less <<
NCT04474626 Sickle Cell Disease|Sickle Cel... More >>l-Beta0-Thalassemia Less << PHASE2 WITHDRAWN 2024-12-31 -

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.15mL

0.43mL

0.22mL

10.77mL

2.15mL

1.08mL

21.53mL

4.31mL

2.15mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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