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[ CAS No. 5129-25-9 ] {[proInfo.proName]}

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3d Animation Molecule Structure of 5129-25-9
Chemical Structure| 5129-25-9
Chemical Structure| 5129-25-9
Structure of 5129-25-9 * Storage: {[proInfo.prStorage]}
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Product Details of [ 5129-25-9 ]

CAS No. :5129-25-9 MDL No. :MFCD09701222
Formula : C9H11NO3 Boiling Point : -
Linear Structure Formula :- InChI Key :MHHWLOGSLYQTTL-UHFFFAOYSA-N
M.W : 181.19 Pubchem ID :13338715
Synonyms :

Safety of [ 5129-25-9 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 5129-25-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5129-25-9 ]

[ 5129-25-9 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 22621-41-6 ]
  • [ 5129-25-9 ]
YieldReaction ConditionsOperation in experiment
With hydrogen;palladium 10% on activated carbon; In 1,4-dioxane; ethanol; water; for 5.5h; The crude product (56.3 g) of compound 196 was dissolved in a mixture of ethanol (200 ml) - dioxane (200 ml) - water (40 ml). A suspension of 10 % palladium carbon (2.82 g) in water (20 ml) was added to the reaction mixture, and the mixture was stirred for 5.5 hours under hydrogen atmosphere. The reaction mixture was filtered through celite pad, and the filtrate was evaporated under reduced pressure. Water (300 ml) was added to the residue, and the reaction mixture was extracted twice with ether. The extract was washed with water, brine and dried over magnesium sulfate. The solvent was evaporated under reduced pressure to give a crude product (48.4 g, 266 mmol) of compound 197 as oil.
  • 3
  • [ 606-45-1 ]
  • [ 5129-25-9 ]
  • [ 22802-67-1 ]
  • 4
  • [ 5129-25-9 ]
  • [ 887573-44-6 ]
  • methyl 3-((5-acetyl-2-chloropyridin-4-yl)amino)-2-methoxybenzoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
68% With hydrogenchloride In ethanol; water at 80℃; for 4h; Inert atmosphere; 4.1 STEP 1: Methyl 3-((5-acetyl-2-chloropyridin-4-yl)amino)-2-methoxybenzoate A mixture of 1-(4,6-dichloropyridin-3-yl)ethan-1-one (1.0 g, 5.3 mmol) and methyl 3-amino-2-methoxybenzoate (0.95 g, 5.3 mmol) in ethanol (20 mL) and concentrated hydrochloric acid (0.20 mL) was stirred for 4 hours at 80°C under a nitrogen atmosphere. The resulting mixture was concentrated under reduced pressure, then purified by silica gel column chromatography eluted with hexane/ ethyl acetate (1:1) to yield methyl 3-((5-acetyl-2-chloropyridin-4-yl)amino)-2-methoxybenzoate (1.2 g, 68%) as a solid.
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