Purity | Size | Price | VIP Price | USA Stock *0-1 Day | Global Stock *5-7 Days | Quantity | |||||
{[ item.p_purity ]} | {[ item.pr_size ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} | {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]} | {[ item.pr_usastock ]} | Inquiry - | {[ item.pr_chinastock ]} | Inquiry - |
* Storage: {[proInfo.prStorage]}
CAS No. : | 5367-32-8 | MDL No. : | MFCD00007167 |
Formula : | C8H9NO3 | Boiling Point : | 280.8°C at 760 mmHg |
Linear Structure Formula : | - | InChI Key : | - |
M.W : | 167.16 g/mol | Pubchem ID : | 79330 |
Synonyms : |
|
Signal Word: | Warning | Class: | N/A |
Precautionary Statements: | P280-P305+P351+P338 | UN#: | N/A |
Hazard Statements: | H302 | Packing Group: | N/A |
GHS Pictogram: |
![]() |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
80% | at 80℃; for 8 h; | General procedure: Nitro aromatic (1.0 mmol), B2(OH)4 (5.0 equiv, 5.0 mmol), and H2O (3.0 mL) were added in a10 mL tube. The reaction mixture was stirred at 80 °C for 8 h. When the reaction was completemonitored by TLC, the mixture was cooled to room temperature, extracted with ethyl acetate (3 ×20 mL). The combined organic phase was dried over anhydrous Na2SO4, filtered, andconcentrated under reduced pressure. The residue was purified by silica gel columnchromatography. |
75% | With tetrahydroxydiboron; 5%-palladium/activated carbon; water In acetonitrile at 50℃; for 24 h; | General procedure: Nitrobenzene (0.6mmol), 5wtpercent Pd/C (0.5mmol percent, 0.003mmol), H2O (10 equiv, 6.0mmol), B2(OH)4 (3.3 equiv, 2.0mmol), and CH3CN (1.0mL) were added in a 10mL tube. The reaction mixture was stirred at 50°C for 24h. When the reaction was complete monitored by TLC, the mixture was cooled to room temperature. Water (5mL) was added, and extracted with EtOAc (3×5mL). The combined organic phase was dried over anhydrous Na2SO4, filtered, and concentrated under reduced pressure. The residue was purified by silica gel column chromatography to give aniline 2a (55mg, 99percent). |
16.5 g | With palladium on activated charcoal; hydrogen In methanol for 0.25 h; | EXAMPLE 1396-((l-(2-(3-Fluoro-6-methoxy-8-methylquinolin-4-yl)ethyl)-2- oxabicyclo[2.2.2]octan-4-ylamino)methyl)-2H-pyrido[3,2-b][l,4]oxazin-3(4H)-oneStep 14-Methoxy-2-methylanilineA solution of 4-methoxy-2-methyl-l -nitrobenzene (20.0 g) in methanol (150 mL) was added Pd/C (1.0 g), then stirred under H2 for about 15 hours until the starting material disappeared on TLC. Filtered and the filtrate was concentrated under reduced pressure to give the title compound (16.5 g), which was used for the next step directly. |
[ 86031-17-6 ]
4-(Hydroxymethyl)-3-nitrophenol
Similarity: 0.93
[ 60463-12-9 ]
3-(Hydroxymethyl)-4-nitrophenol
Similarity: 0.91
[ 50741-92-9 ]
1-Methoxy-2-methyl-4-nitrobenzene
Similarity: 0.90
[ 86031-17-6 ]
4-(Hydroxymethyl)-3-nitrophenol
Similarity: 0.93
[ 60463-12-9 ]
3-(Hydroxymethyl)-4-nitrophenol
Similarity: 0.91
[ 50741-92-9 ]
1-Methoxy-2-methyl-4-nitrobenzene
Similarity: 0.90
[ 50741-92-9 ]
1-Methoxy-2-methyl-4-nitrobenzene
Similarity: 0.90
[ 57559-52-1 ]
4-Methoxy-2-nitrobenzyl Bromide
Similarity: 0.88