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Chemical Structure| 56010-88-9 Chemical Structure| 56010-88-9

Structure of Fomepizole HCl
CAS No.: 56010-88-9

Chemical Structure| 56010-88-9

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Fomepizole is an effective cytochrome P450 (CYP2E1) inhibitor, widely used to prevent the toxic metabolism of methanol and ethylene glycol, commonly used in the treatment of methanol or ethylene glycol poisoning, playing an important role as an antidote in acute poisoning research.

Synonyms: 4-Methylpyrazole hydrochloride; Fomepizole hydrochloride

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Product Details of Fomepizole HCl

CAS No. :56010-88-9
Formula : C4H7ClN2
M.W : 118.56
SMILES Code : CC1=CNN=C1.[H]Cl
Synonyms :
4-Methylpyrazole hydrochloride; Fomepizole hydrochloride
MDL No. :MFCD00012707
InChI Key :PUCXJHNDMYZOHG-UHFFFAOYSA-N
Pubchem ID :11957593

Safety of Fomepizole HCl

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Description
Fomepizole (4-Methylpyrazole) hydrochloride is a potent, orally active inhibitor of cytochrome P450 (CYP2E1) and acts as a competitive inhibitor of alcohol dehydrogenase. Fomepizole hydrochloride effectively prevents the conversion of methanol and ethylene glycol into their toxic metabolites, making it a potential antidote for poisoning by these substances[1].[2].[3].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

8.43mL

1.69mL

0.84mL

42.17mL

8.43mL

4.22mL

84.35mL

16.87mL

8.43mL

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