[ CAS No. 5628-61-5 ] {[proInfo.proName]}

Name: 5628-61-5|4-Methoxy-2,3-dimethylbenzoic acid|98%
Brand: Ambeed
SKU: A134512
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2D 3D

Structure of 5628-61-5 * Storage: {[proInfo.prStorage]}

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Quality Control of [ 5628-61-5 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 5628-61-5 ]

SDS Specification

Alternatived Products of [ 5628-61-5 ]

Product Details of [ 5628-61-5 ]

CAS No. :	5628-61-5	MDL No. :	MFCD06203271
Formula :	C₁₀H₁₂O₃	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	IPCTTXWQWCZEOE-UHFFFAOYSA-N
M.W :	180.20	Pubchem ID :	13440081
Synonyms :

Safety of [ 5628-61-5 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P261-P305+P351+P338	UN#:	N/A
Hazard Statements:	H315-H319-H335	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 5628-61-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 5628-61-5 ]
Downstream synthetic route of [ 5628-61-5 ]

[ 5628-61-5 ] Synthesis Path-Upstream 1~17

1
[ 38998-17-3 ]
[ 5628-61-5 ]

Yield	Reaction Conditions	Operation in experiment
98%	With sodium chlorite; sodium dihydrogenphosphate In water; dimethyl sulfoxide at 20 - 40℃; for 2 h;	4-Methoxy-2,3-dimethylbenzoic acid 60.0 g of 2,3-dimethyl-4-methoxybenzaldehyde (DI) are dissolved in 1.20 l of dimethyl sulfoxide. A solution of 131.5 g of sodium dihydrogenphosphate and 132.2 g of sodium chlorite in 480 ml of water is subsequently added dropwise, during which the temperature of the reaction batch is kept below 40° C. The reaction mixture is then stirred at room temperature for a further 2 hours. For work-up, the suspension is diluted with 2.0 l of water and stirred for a further hour. The resultant precipitate is filtered, washed with water and dried at 100° C. in vacuo, giving 65.0 g of the title compound as colourless solid having a melting point of 214° C. (MS: 181.2 (MH⁺)).
80%	With sodium chlorite; sodium dihydrogenphosphate In dimethyl sulfoxide at 40℃; for 1 h;	4-Methoxy-2,3-dimethylbenzoic acid (G1)Compound G1 can be prepared from commercially available 4-methoxy-2,3-dimethylbenzaldehyde (H1) in accordance with EP1666473 A1, p. 41.

Reference： [1] Patent: US2011/60050, 2011, A1, . Location in patent: Page/Page column 4
[2] Patent: US2011/224302, 2011, A1, . Location in patent: Page/Page column 10; 15
[3] Bioorganic Chemistry, 1996, vol. 24, # 4, p. 386 - 400
[4] Patent: EP1666473, 2006, A1, . Location in patent: Page/Page column 41

2
[ 2944-49-2 ]
[ 201230-82-2 ]
[ 5628-61-5 ]

Reference： [1] Chemical Communications, 2005, # 4, p. 486 - 488

3
[ 97888-77-2 ]
[ 5628-61-5 ]

Reference： [1] Acta Chimica Hungarica, 1985, vol. 118, # 1, p. 63 - 70

4
[ 16819-01-5 ]
[ 5628-61-5 ]

Reference： [1] Journal of Organic Chemistry, 1960, vol. 25, p. 334 - 343

5
[ 109185-38-8 ]
[ 5628-61-5 ]

Reference： [1] Journal of Organic Chemistry, 1960, vol. 25, p. 334 - 343

6
[ 52962-97-7 ]
[ 5628-61-5 ]

Reference： [1] Bulletin de la Societe Chimique de France, 1963, p. 1813 - 1817
[2] Bulletin de la Societe Chimique de France, 1963, p. 1813 - 1817

7
[ 90557-85-0 ]
[ 5628-61-5 ]

Reference： [1] Bulletin de la Societe Chimique de France, 1963, p. 1813 - 1817
[2] Bulletin de la Societe Chimique de France, 1963, p. 1813 - 1817

8
[ 90564-15-1 ]
[ 5628-61-5 ]

Reference： [1] Bulletin de la Societe Chimique de France, 1963, p. 1813 - 1817
[2] Bulletin de la Societe Chimique de France, 1963, p. 1813 - 1817

9
[ 80879-86-3 ]
[ 5628-61-5 ]

Reference： [1] Bulletin de la Societe Chimique de France, 1963, p. 1813 - 1817
[2] Bulletin de la Societe Chimique de France, 1963, p. 1813 - 1817

10
[ 134-98-5 ]
[ 5628-61-5 ]

Reference： [1] Bulletin de la Societe Chimique de France, 1963, p. 1813 - 1817
[2] Bulletin de la Societe Chimique de France, 1963, p. 1813 - 1817

11
[ 97900-39-5 ]
[ 5628-61-5 ]

Reference： [1] Acta Chimica Hungarica, 1985, vol. 118, # 1, p. 63 - 70

12
[ 5628-62-6 ]
[ 5628-61-5 ]